Suppression of reactive oxygen species and neurodegeneration by the PGC-1 transcriptional coactivators J St-Pierre, S Drori, M Uldry, JM Silvaggi, J Rhee, S Jäger, C Handschin, ... Cell 127 (2), 397-408, 2006 | 2557 | 2006 |
Parkinson disease epidemiology, pathology, genetics, and pathophysiology DK Simon, CM Tanner, P Brundin Clinics in geriatric medicine 36 (1), 1-12, 2020 | 1123 | 2020 |
High aggregate burden of somatic mtDNA point mutations in aging and Alzheimer’s disease brain MT Lin, DK Simon, CH Ahn, LM Kim, MF Beal Human molecular genetics 11 (2), 133-145, 2002 | 449 | 2002 |
Development of topographic order in the mammalian retinocollicular projection DK Simon, DD O'leary Journal of Neuroscience 12 (4), 1212-1232, 1992 | 416 | 1992 |
N-methyl-D-aspartate receptor antagonists disrupt the formation of a mammalian neural map. DK Simon, GT Prusky, DD O'leary, M Constantine-Paton Proceedings of the National Academy of Sciences 89 (22), 10593-10597, 1992 | 368 | 1992 |
Dystonia D Tarsy, DK Simon New England Journal of Medicine 355 (8), 818-829, 2006 | 365 | 2006 |
Meta‐analysis of Parkinson's Disease: Identification of a novel locus, RIT2 N Pankratz, GW Beecham, AL DeStefano, TM Dawson, KF Doheny, ... Annals of neurology 71 (3), 370-384, 2012 | 354 | 2012 |
Non-invasive brain stimulation for Parkinson’s disease: a systematic review and meta-analysis of the literature F Fregni, DK Simon, A Wu, A Pascual-Leone Journal of Neurology, Neurosurgery & Psychiatry 76 (12), 1614-1623, 2005 | 346 | 2005 |
A randomized clinical trial of high-dosage coenzyme Q10 in early Parkinson disease: no evidence of benefit MF Beal, D Oakes, I Shoulson, C Henchcliffe, WR Galpern, R Haas, ... JAMA neurology 71 (5), 543-552, 2014 | 319 | 2014 |
Trial of cinpanemab in early Parkinson’s disease AE Lang, AD Siderowf, EA Macklin, W Poewe, DJ Brooks, HH Fernandez, ... New England Journal of Medicine 387 (5), 408-420, 2022 | 255 | 2022 |
Mitochondrial cyclic AMP response element-binding protein (CREB) mediates mitochondrial gene expression and neuronal survival J Lee, CH Kim, DK Simon, LR Aminova, AY Andreyev, YE Kushnareva, ... Journal of Biological Chemistry 280 (49), 40398-40401, 2005 | 232 | 2005 |
Revisiting protein aggregation as pathogenic in sporadic Parkinson and Alzheimer diseases AJ Espay, JA Vizcarra, L Marsili, AE Lang, DK Simon, A Merola, ... Neurology 92 (7), 329-337, 2019 | 229 | 2019 |
A randomized clinical trial of coenzyme Q10 and GPI-1485 in early Parkinson disease Ninds Net-PD Investigators Neurology 68 (1), 20-28, 2007 | 226 | 2007 |
Mitochondrial disorders: clinical and genetic features DK Simon, MD, PhD, DR Johns, MD Annual review of medicine 50 (1), 111-127, 1999 | 213 | 1999 |
Association of cumulative lead exposure with Parkinson’s disease MG Weisskopf, J Weuve, H Nie, MH Saint-Hilaire, L Sudarsky, DK Simon, ... Environmental health perspectives 118 (11), 1609-1613, 2010 | 204 | 2010 |
Multifocal repetitive TMS for motor and mood symptoms of Parkinson disease: a randomized trial M Brys, MD Fox, S Agarwal, M Biagioni, G Dacpano, P Kumar, E Pirraglia, ... Neurology 87 (18), 1907-1915, 2016 | 189 | 2016 |
Effect of creatine monohydrate on clinical progression in patients with Parkinson disease: a randomized clinical trial K Kieburtz, BC Tilley, JJ Elm, D Babcock, R Hauser, GW Ross, ... Jama 313 (6), 584-593, 2015 | 185 | 2015 |
Noninvasive brain stimulation for Parkinson’s disease and dystonia AD Wu, F Fregni, DK Simon, C Deblieck, A Pascual-Leone Neurotherapeutics 5 (2), 345-361, 2008 | 169 | 2008 |
Biomarker‐driven phenotyping in Parkinson's disease: a translational missing link in disease‐modifying clinical trials AJ Espay, MA Schwarzschild, CM Tanner, HH Fernandez, DK Simon, ... Movement Disorders 32 (3), 319-324, 2017 | 153 | 2017 |
Genetic risk of Parkinson disease and progression: an analysis of 13 longitudinal cohorts H Iwaki, C Blauwendraat, HL Leonard, G Liu, J Maple-Grødem, JC Corvol, ... Neurology: Genetics 5 (4), e348, 2019 | 152 | 2019 |