| Mutational heterogeneity in cancer and the search for new cancer-associated genes MS Lawrence, P Stojanov, P Polak, GV Kryukov, K Cibulskis, ... Nature 499 (7457), 214-218, 2013 | 6067 | 2013 |
| The repertoire of mutational signatures in human cancer LB Alexandrov, J Kim, NJ Haradhvala, MN Huang, AW Tian Ng, Y Wu, ... Nature 578 (7793), 94-101, 2020 | 2925 | 2020 |
| Comprehensive molecular characterization of urothelial bladder carcinoma Cancer Genome Atlas Research Network Nature 507 (7492), 315, 2014 | 2774 | 2014 |
| Pan-cancer analysis of whole genomes Nature 578 (7793), 82-93, 2020 | 2253 | 2020 |
| An APOBEC cytidine deaminase mutagenesis pattern is widespread in human cancers SA Roberts, MS Lawrence, LJ Klimczak, SA Grimm, D Fargo, P Stojanov, ... Nature genetics 45 (9), 970-976, 2013 | 1286 | 2013 |
| Integrated genomic and molecular characterization of cervical cancer Cancer Genome Atlas Research Network Nature 543 (7645), 378, 2017 | 1196* | 2017 |
| The somatic genomic landscape of chromophobe renal cell carcinoma CF Davis, CJ Ricketts, M Wang, L Yang, AD Cherniack, H Shen, C Buhay, ... Cancer cell 26 (3), 319-330, 2014 | 869 | 2014 |
| Patterns of somatic structural variation in human cancer genomes Y Li, ND Roberts, JA Wala, O Shapira, SE Schumacher, K Kumar, ... Nature 578 (7793), 112-121, 2020 | 823 | 2020 |
| Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing I Cortés-Ciriano, JJK Lee, R Xi, D Jain, YL Jung, L Yang, D Gordenin, ... Nature genetics 52 (3), 331-341, 2020 | 642 | 2020 |
| Clustered mutations in yeast and in human cancers can arise from damaged long single-strand DNA regions SA Roberts, J Sterling, C Thompson, S Harris, D Mav, R Shah, ... Molecular cell 46 (4), 424-435, 2012 | 453 | 2012 |
| Hypermutation in human cancer genomes: footprints and mechanisms SA Roberts, DA Gordenin Nature Reviews Cancer 14 (12), 786-800, 2014 | 451 | 2014 |
| An APOBEC3A hypermutation signature is distinguishable from the signature of background mutagenesis by APOBEC3B in human cancers K Chan, SA Roberts, LJ Klimczak, JF Sterling, N Saini, EP Malc, J Kim, ... Nature genetics 47 (9), 1067-1072, 2015 | 443 | 2015 |
| Essential roles for polymerase θ-mediated end joining in the repair of chromosome breaks DW Wyatt, W Feng, MP Conlin, MJ Yousefzadeh, SA Roberts, ... Molecular cell 63 (4), 662-673, 2016 | 334 | 2016 |
| Ku is a 5′-dRP/AP lyase that excises nucleotide damage near broken ends SA Roberts, N Strande, MD Burkhalter, C Strom, JM Havener, P Hasty, ... Nature 464 (7292), 1214-1217, 2010 | 256 | 2010 |
| APOBEC3A and APOBEC3B preferentially deaminate the lagging strand template during DNA replication JI Hoopes, LM Cortez, TM Mertz, EP Malc, PA Mieczkowski, SA Roberts Cell reports 14 (6), 1273-1282, 2016 | 229 | 2016 |
| Break-induced replication is a source of mutation clusters underlying kataegis CJ Sakofsky, SA Roberts, E Malc, PA Mieczkowski, MA Resnick, ... Cell reports 7 (5), 1640-1648, 2014 | 186 | 2014 |
| Chromosomal landscape of UV damage formation and repair at single-nucleotide resolution P Mao, MJ Smerdon, SA Roberts, JJ Wyrick Proceedings of the National Academy of Sciences 113 (32), 9057-9062, 2016 | 165 | 2016 |
| Analysis of Drosophila STING reveals an evolutionarily conserved antimicrobial function M Martin, A Hiroyasu, RM Guzman, SA Roberts, AG Goodman Cell reports 23 (12), 3537-3550. e6, 2018 | 159 | 2018 |
| Mechanistic basis for microhomology identification and genome scarring by polymerase theta J Carvajal-Garcia, JE Cho, P Carvajal-Garcia, W Feng, RD Wood, ... Proceedings of the National Academy of Sciences 117 (15), 8476-8485, 2020 | 153 | 2020 |
| ETS transcription factors induce a unique UV damage signature that drives recurrent mutagenesis in melanoma P Mao, AJ Brown, S Esaki, S Lockwood, GMK Poon, MJ Smerdon, ... Nature communications 9 (1), 2626, 2018 | 146 | 2018 |
