Differentiation and reversal of malignant changes in colon cancer through PPARγ P Sarraf, E Mueller, D Jones, FJ King, DJ DeAngelo, JB Partridge, ... Nature medicine 4 (9), 1046-1052, 1998 | 1269 | 1998 |
The ultimate speed of magnetic switching in granular recording media I Tudosa, C Stamm, AB Kashuba, F King, HC Siegmann, J Stöhr, G Ju, ... Nature 428 (6985), 831-833, 2004 | 395 | 2004 |
An efficient rapid system for profiling the cellular activities of molecular libraries JS Melnick, J Janes, S Kim, JY Chang, DG Sipes, D Gunderson, L Jarnes, ... Proceedings of the National Academy of Sciences 103 (9), 3153-3158, 2006 | 207 | 2006 |
TASL is the SLC15A4-associated adaptor for IRF5 activation by TLR7–9 LX Heinz, JE Lee, U Kapoor, F Kartnig, V Sedlyarov, K Papakostas, ... Nature 581 (7808), 316-322, 2020 | 184 | 2020 |
Dark chemical matter as a promising starting point for drug lead discovery AM Wassermann, E Lounkine, D Hoepfner, G Le Goff, FJ King, C Studer, ... Nature chemical biology 11 (12), 958-966, 2015 | 145 | 2015 |
Genome-scale functional profiling of the mammalian AP-1 signaling pathway SK Chanda, S White, AP Orth, R Reisdorph, L Miraglia, RS Thomas, ... Proceedings of the National Academy of Sciences 100 (21), 12153-12158, 2003 | 129 | 2003 |
Dual ALK and CDK4/6 Inhibition Demonstrates Synergy against Neuroblastoma AC Wood, K Krytska, HT Ryles, NR Infarinato, R Sano, TD Hansel, ... Clinical Cancer Research 23 (11), 2856-2868, 2017 | 120 | 2017 |
Evidence-based and quantitative prioritization of tool compounds in phenotypic drug discovery Y Wang, A Cornett, FJ King, Y Mao, F Nigsch, CG Paris, G McAllister, ... Cell chemical biology 23 (7), 862-874, 2016 | 62 | 2016 |
Compound profiling devices, systems, and related methods JY Chang, JK Mainquist, RC Downs, JS Caldwell, FJ King US Patent App. 11/841,880, 2009 | 62 | 2009 |
DEF-1, a novel Src SH3 binding protein that promotes adipogenesis in fibroblastic cell lines FJ King, E Hu, DF Harris, P Sarraf, BM Spiegelman, TM Roberts Molecular and cellular biology, 1999 | 57 | 1999 |
Seeing the light: luminescent reporter gene assays L J Miraglia, F J King, R Damoiseaux Combinatorial chemistry & high throughput screening 14 (8), 648-657, 2011 | 49 | 2011 |
Learning from the data: mining of large high-throughput screening databases SF Yan, FJ King, Y He, JS Caldwell, Y Zhou Journal of chemical information and modeling 46 (6), 2381-2395, 2006 | 48 | 2006 |
Compound profiling devices, systems, and related methods J Chang, J Mainquist, R Downs, J Caldwell, F King US Patent App. 11/387,459, 2006 | 48 | 2006 |
Large-scale annotation of small-molecule libraries using public databases Y Zhou, B Zhou, K Chen, SF Yan, FJ King, S Jiang, EA Winzeler Journal of chemical information and modeling 47 (4), 1386-1394, 2007 | 40 | 2007 |
Discovering highly selective and diverse PPAR-delta agonists by ligand based machine learning and structural modeling B Da’adoosh, D Marcus, A Rayan, F King, J Che, A Goldblum Scientific reports 9 (1), 1106, 2019 | 34 | 2019 |
Chemical and biological properties of frequent screening hits J Che, FJ King, B Zhou, Y Zhou Journal of chemical information and modeling 52 (4), 913-926, 2012 | 31 | 2012 |
Pathway reporter assays reveal small molecule mechanisms of action FJ King, DW Selinger, FA Mapa, J Janes, H Wu, TR Smith, QY Wang, ... JALA: Journal of the Association for Laboratory Automation 14 (6), 374-382, 2009 | 29 | 2009 |
Multiplexed reporter gene assays: monitoring the cell viability and the compound kinetics on luciferase activity MC Didiot, S Serafini, MJ Pfeifer, FJ King, CN Parker Journal of biomolecular screening 16 (7), 786-793, 2011 | 21 | 2011 |
Drug target prediction through deep learning functional representation of gene signatures H Chen, FJ King, B Zhou, Y Wang, CJ Canedy, J Hayashi, Y Zhong, ... Nature communications 15 (1), 1853, 2024 | 20 | 2024 |
Differential tumor cytotoxicity compounds and compositions J Chyba, Q Devereax, G Hampton, F King US Patent 7,125,997, 2006 | 20 | 2006 |