Single-cell multi-omics analysis of the immune response in COVID-19 E Stephenson, G Reynolds, RA Botting, FJ Calero-Nieto, MD Morgan, ... Nature medicine 27 (5), 904-916, 2021 | 642* | 2021 |
N6-methyladenosine (m6A) recruits and repels proteins to regulate mRNA homeostasis RR Edupuganti, S Geiger, RGH Lindeboom, H Shi, PJ Hsu, Z Lu, ... Nature structural & molecular biology 24 (10), 870-878, 2017 | 560 | 2017 |
The rules and impact of nonsense-mediated mRNA decay in human cancers RGH Lindeboom, F Supek, B Lehner Nature genetics 48 (10), 1112-1118, 2016 | 494 | 2016 |
Local and systemic responses to SARS-CoV-2 infection in children and adults M Yoshida, KB Worlock, N Huang, RGH Lindeboom, CR Butler, ... Nature 602 (7896), 321-327, 2022 | 292 | 2022 |
The impact of nonsense-mediated mRNA decay on genetic disease, gene editing and cancer immunotherapy RGH Lindeboom, M Vermeulen, B Lehner, F Supek Nature genetics 51 (11), 1645-1651, 2019 | 243 | 2019 |
To NMD or not to NMD: nonsense-mediated mRNA decay in cancer and other genetic diseases F Supek, B Lehner, RGH Lindeboom Trends in Genetics 37 (7), 657-668, 2021 | 192 | 2021 |
Probing the tumor suppressor function of BAP1 in CRISPR-engineered human liver organoids B Artegiani, L van Voorthuijsen, RGH Lindeboom, D Seinstra, I Heo, ... Cell Stem Cell 24 (6), 927-943. e6, 2019 | 192 | 2019 |
Single-molecule imaging uncovers rules governing nonsense-mediated mRNA decay TA Hoek, D Khuperkar, RGH Lindeboom, S Sonneveld, BMP Verhagen, ... Molecular cell 75 (2), 324-339. e11, 2019 | 160 | 2019 |
Integrative multi‐omics analysis of intestinal organoid differentiation RGH Lindeboom, L van Voorthuijsen, KC Oost, MJ Rodríguez‐Colman, ... Molecular systems biology 14 (6), e8227, 2018 | 135 | 2018 |
ZMYND8 co-localizes with NuRD on target genes and regulates poly (ADP-ribose)-dependent recruitment of GATAD2A/NuRD to sites of DNA damage CG Spruijt, MS Luijsterburg, R Menafra, RGH Lindeboom, PWTC Jansen, ... Cell reports 17 (3), 783-798, 2016 | 123 | 2016 |
A spatially resolved atlas of the human lung characterizes a gland-associated immune niche E Madissoon, AJ Oliver, V Kleshchevnikov, A Wilbrey-Clark, K Polanski, ... Nature Genetics 55 (1), 66-77, 2023 | 112 | 2023 |
Towards a human cell atlas: taking notes from the past RGH Lindeboom, A Regev, SA Teichmann Trends in Genetics 37 (7), 625-630, 2021 | 85 | 2021 |
Global absolute quantification reveals tight regulation of protein expression in single Xenopus eggs AH Smits, RGH Lindeboom, M Perino, SJ van Heeringen, GJC Veenstra, ... Nucleic acids research 42 (15), 9880-9891, 2014 | 71 | 2014 |
Quantification of proteins and histone marks in Drosophila embryos reveals stoichiometric relationships impacting chromatin regulation J Bonnet, RGH Lindeboom, D Pokrovsky, G Stricker, MH Celik, ... Developmental cell 51 (5), 632-644. e6, 2019 | 56 | 2019 |
Liver colonization by colorectal cancer metastases requires YAP-controlled plasticity at the micrometastatic stage MC Heinz, NA Peters, KC Oost, RGH Lindeboom, L van Voorthuijsen, ... Cancer research 82 (10), 1953-1968, 2022 | 48 | 2022 |
Human SARS-CoV-2 challenge uncovers local and systemic response dynamics RGH Lindeboom, KB Worlock, LM Dratva, M Yoshida, D Scobie, ... Nature, 1-10, 2024 | 47* | 2024 |
Hydroxychloroquine inhibits the trained innate immune response to interferons N Rother, C Yanginlar, RGH Lindeboom, S Bekkering, MMT van Leent, ... Cell Reports Medicine 1 (9), 2020 | 46* | 2020 |
RNF 43 truncations trap CK 1 to drive niche‐independent self‐renewal in cancer M Spit, N Fenderico, I Jordens, T Radaszkiewicz, RGH Lindeboom, ... The EMBO Journal 39 (18), e103932, 2020 | 46 | 2020 |
Recruitment of the mammalian histone-modifying EMSY complex to target genes is regulated by ZNF131 RA Varier, EC de Santa Pau, P Van Der Groep, RGH Lindeboom, ... Journal of Biological Chemistry 291 (14), 7313-7324, 2016 | 43 | 2016 |
Dandelion uses the single-cell adaptive immune receptor repertoire to explore lymphocyte developmental origins C Suo, K Polanski, E Dann, RGH Lindeboom, R Vilarrasa-Blasi, ... Nature Biotechnology 42 (1), 40-51, 2024 | 34 | 2024 |