| FADD and caspase-8 mediate priming and activation of the canonical and noncanonical Nlrp3 inflammasomes P Gurung, PK Anand, RK Malireddi, L Vande Walle, N Van Opdenbosch, ... The Journal of Immunology 192 (4), 1835-1846, 2014 | 593 | 2014 |
| RIPK1 blocks early postnatal lethality mediated by caspase-8 and RIPK3 CP Dillon, R Weinlich, DA Rodriguez, JG Cripps, G Quarato, P Gurung, ... Cell 157 (5), 1189-1202, 2014 | 590 | 2014 |
| Mitochondria: diversity in the regulation of the NLRP3 inflammasome P Gurung, JR Lukens, TD Kanneganti Trends in molecular medicine 21 (3), 193-201, 2015 | 410 | 2015 |
| Critical role for the DNA sensor AIM2 in stem cell proliferation and cancer SM Man, Q Zhu, L Zhu, Z Liu, R Karki, A Malik, D Sharma, L Li, ... Cell 162 (1), 45-58, 2015 | 339 | 2015 |
| Recent advances in lipopolysaccharide recognition systems L Mazgaeen, P Gurung International journal of molecular sciences 21 (2), 379, 2020 | 328 | 2020 |
| Dietary modulation of the microbiome affects autoinflammatory disease JR Lukens, P Gurung, P Vogel, GR Johnson, RA Carter, DJ McGoldrick, ... Nature 516 (7530), 246-249, 2014 | 327 | 2014 |
| Concerted activation of the AIM2 and NLRP3 inflammasomes orchestrates host protection against Aspergillus infection R Karki, SM Man, RKS Malireddi, P Gurung, P Vogel, M Lamkanfi, ... Cell host & microbe 17 (3), 357-368, 2015 | 281 | 2015 |
| Toll or interleukin-1 receptor (TIR) domain-containing adaptor inducing interferon-β (TRIF)-mediated caspase-11 protease production integrates Toll-like receptor 4 (TLR4 … P Gurung, RKS Malireddi, PK Anand, D Demon, LV Walle, Z Liu, P Vogel, ... Journal of Biological Chemistry 287 (41), 34474-34483, 2012 | 281 | 2012 |
| Innate immune priming in the absence of TAK1 drives RIPK1 kinase activity–independent pyroptosis, apoptosis, necroptosis, and inflammatory disease RK Malireddi, P Gurung, S Kesavardhana, P Samir, A Burton, ... Journal of Experimental Medicine 217 (3), 2020 | 270 | 2020 |
| Activation of the NLRP1b inflammasome independently of ASC-mediated caspase-1 autoproteolysis and speck formation N Van Opdenbosch, P Gurung, L Vande Walle, A Fossoul, TD Kanneganti, ... Nature communications 5 (1), 3209, 2014 | 268 | 2014 |
| TAK1 restricts spontaneous NLRP3 activation and cell death to control myeloid proliferation RKS Malireddi, P Gurung, J Mavuluri, TK Dasari, JM Klco, H Chi, ... Journal of Experimental Medicine 215 (4), 1023-1034, 2018 | 215 | 2018 |
| Novel roles for caspase-8 in IL-1β and inflammasome regulation P Gurung, TD Kanneganti The American journal of pathology 185 (1), 17-25, 2015 | 199 | 2015 |
| Chronic TLR stimulation controls NLRP3 inflammasome activation through IL-10 mediated regulation of NLRP3 expression and caspase-8 activation P Gurung, B Li, RK Subbarao Malireddi, M Lamkanfi, TL Geiger, ... Scientific reports 5 (1), 14488, 2015 | 177 | 2015 |
| NALP3 inflammasome upregulation and CASP1 cleavage of the glucocorticoid receptor cause glucocorticoid resistance in leukemia cells SW Paugh, EJ Bonten, D Savic, LB Ramsey, WE Thierfelder, P Gurung, ... Nature genetics 47 (6), 607-614, 2015 | 171 | 2015 |
| Protective roles for caspase-8 and cFLIP in adult homeostasis R Weinlich, A Oberst, CP Dillon, LJ Janke, S Milasta, JR Lukens, ... Cell reports 5 (2), 340-348, 2013 | 170 | 2013 |
| Role of inflammasomes in host defense against Citrobacter rodentium infection Z Liu, MH Zaki, P Vogel, P Gurung, BB Finlay, W Deng, M Lamkanfi, ... Journal of Biological chemistry 287 (20), 16955-16964, 2012 | 170 | 2012 |
| Cutting edge: STING mediates protection against colorectal tumorigenesis by governing the magnitude of intestinal inflammation Q Zhu, SM Man, P Gurung, Z Liu, P Vogel, M Lamkanfi, TD Kanneganti The Journal of Immunology 193 (10), 4779-4782, 2014 | 158 | 2014 |
| An NLRP3 inflammasome–triggered Th2-biased adaptive immune response promotes leishmaniasis P Gurung, R Karki, P Vogel, M Watanabe, M Bix, M Lamkanfi, ... The Journal of clinical investigation 125 (3), 1329-1338, 2015 | 138 | 2015 |
| NLRP3 inflammasome plays a redundant role with caspase 8 to promote IL-1β–mediated osteomyelitis P Gurung, A Burton, TD Kanneganti Proceedings of the National Academy of Sciences 113 (16), 4452-4457, 2016 | 128 | 2016 |
| The NLRP12 sensor negatively regulates autoinflammatory disease by modulating interleukin-4 production in T cells JR Lukens, P Gurung, PJ Shaw, MJ Barr, MH Zaki, SA Brown, P Vogel, ... Immunity 42 (4), 654-664, 2015 | 124 | 2015 |