TORC1 inhibition enhances immune function and reduces infections in the elderly JB Mannick, M Morris, HUP Hockey, G Roma, M Beibel, K Kulmatycki, ... Science translational medicine 10 (449), eaaq1564, 2018 | 409 | 2018 |
Logic-based models for the analysis of cell signaling networks MK Morris, J Saez-Rodriguez, PK Sorger, DA Lauffenburger Biochemistry 49 (15), 3216-3224, 2010 | 405 | 2010 |
CellNOptR: a flexible toolkit to train protein signaling networks to data using multiple logic formalisms C Terfve, T Cokelaer, D Henriques, A MacNamara, E Goncalves, ... BMC systems biology 6 (1), 133, 2012 | 249 | 2012 |
Training signaling pathway maps to biochemical data with constrained fuzzy logic: quantitative analysis of liver cell responses to inflammatory stimuli MK Morris, J Saez-Rodriguez, DC Clarke, PK Sorger, DA Lauffenburger PLoS Comput Biol 7 (3), e1001099-e1001099, 2011 | 169 | 2011 |
Comparing signaling networks between normal and transformed hepatocytes using discrete logical models J Saez-Rodriguez, LG Alexopoulos, MS Zhang, MK Morris, ... Cancer research 71 (16), 5400-5411, 2011 | 167 | 2011 |
Age-related gene expression signature in rats demonstrate early, late, and linear transcriptional changes from multiple tissues T Shavlakadze, M Morris, J Fang, SX Wang, J Zhu, W Zhou, WT Herman, ... Cell reports 28 (12), 3263-3273. e3, 2019 | 144 | 2019 |
Protein Signatures of Centenarians and Their Offspring Suggest Centenarians Age Slower than Other Humans P Sebastiani, A Federico, M Morris, A Gurinovich, T Toshiko, A Bhutkar, ... CELL-REPORTS-D-19-04587, 2019 | 69 | 2019 |
Phosphoproteomics in drug discovery MK Morris, A Chi, IN Melas, LG Alexopoulos Drug discovery today 19 (4), 425-432, 2014 | 42 | 2014 |
Systematic Analysis of Quantitative Logic Model Ensembles Predicts Drug Combination Effects on Cell Signaling Networks MK Morris, DC Clarke, LC Osimiri, DA Lauffenburger CPT: Pharmacometrics & Systems Pharmacology 5 (10), 544-553, 2016 | 38 | 2016 |
A serum protein signature of APOE genotypes in centenarians P Sebastiani, S Monti, M Morris, A Gurinovich, T Toshiko, SL Andersen, ... Aging cell 18 (6), e13023, 2019 | 33 | 2019 |
Normalization and Statistical Analysis of Multiplexed Bead-based Immunoassay Data Using Mixed-effects Modeling DC Clarke, MK Morris, DA Lauffenburger Molecular & Cellular Proteomics 12 (1), 245-262, 2013 | 30 | 2013 |
Non Linear Programming (NLP) formulation for quantitative modeling of protein signal transduction pathways A Mitsos, IN Melas, MK Morris, J Saez-Rodriguez, DA Lauffenburger, ... | 21 | 2012 |
Genes related to emphysema are enriched for ubiquitination pathways S Stepaniants, IM Wang, Y Boie, J Mortimer, B Kennedy, M Elliott, ... BMC pulmonary medicine 14 (1), 187, 2014 | 18 | 2014 |
Construction of cell type-specific logic models of signaling networks using CellNOpt MK Morris, I Melas, J Saez-Rodriguez Computational Toxicology, 179-214, 2013 | 13 | 2013 |
Querying quantitative logic models (Q2LM) to study intracellular signaling networks and cell‐cytokine interactions MK Morris, Z Shriver, R Sasisekharan, DA Lauffenburger Biotechnology journal 7 (3), 374-386, 2012 | 11 | 2012 |
Benchmarking network algorithms for contextualizing genes of interest A Hill, S Gleim, F Kiefer, F Sigoillot, J Loureiro, J Jenkins, MK Morris PLOS Computational Biology 15 (12), e1007403, 2019 | 9 | 2019 |
Pharmacological Inhibition of O-GlcNAcase Does Not Increase Sensitivity of Glucocorticoid Receptor-Mediated Transrepression PJ Stivers, L Harmonay, A Hicks, H Mehmet, M Morris, GM Robinson, ... PloS one 10 (12), 2015 | 5 | 2015 |
Methods of enhancing immune response J Mannick, M Morris US Patent 10,441,584, 2019 | 4 | 2019 |
Mitochondrial dysfunction in the aged lung and COPD: A role for mitochondrial calcium? S Srivastava, K Subramanian, K Choy, AM Ledo, O Bonneau, ... ERJ Open Research 6 (suppl 5), 2020 | 1 | 2020 |
Development of constrained fuzzy logic for modeling biological regulatory networks and predicting contextual therapeutic effects MK Morris Massachusetts Institute of Technology, 2012 | 1 | 2012 |