Phase separation of signaling molecules promotes T cell receptor signal transduction X Su, JA Ditlev, E Hui, W Xing, S Banjade, J Okrut, DS King, J Taunton, ... Science 352 (6285), 595-599, 2016 | 1156 | 2016 |
Stoichiometry controls activity of phase-separated clusters of actin signaling proteins LB Case, X Zhang, JA Ditlev, MK Rosen Science 363 (6431), 1093-1097, 2019 | 420 | 2019 |
Who's in and who's out—compositional control of biomolecular condensates JA Ditlev, LB Case, MK Rosen Journal of molecular biology 430 (23), 4666-4684, 2018 | 357 | 2018 |
Preparing the “soil”: the primary tumor induces vasculature reorganization in the sentinel lymph node before the arrival of metastatic cancer cells CN Qian, B Berghuis, G Tsarfaty, MB Bruch, EJ Kort, J Ditlev, I Tsarfaty, ... Cancer research 66 (21), 10365-10376, 2006 | 340 | 2006 |
A molecular classification of papillary renal cell carcinoma XJ Yang, MH Tan, HL Kim, JA Ditlev, MW Betten, CE Png, EJ Kort, ... Cancer research 65 (13), 5628-5637, 2005 | 272 | 2005 |
Regulation of transmembrane signaling by phase separation LB Case, JA Ditlev, MK Rosen Annual review of biophysics 48 (1), 465-494, 2019 | 268 | 2019 |
Genomic expression and single-nucleotide polymorphism profiling discriminates chromophobe renal cell carcinoma and oncocytoma MH Tan, CF Wong, HL Tan, XJ Yang, J Ditlev, D Matsuda, SK Khoo, ... BMC cancer 10, 1-12, 2010 | 112 | 2010 |
A composition-dependent molecular clutch between T cell signaling condensates and actin JA Ditlev, AR Vega, DV Köster, X Su, T Tani, AM Lakoduk, RD Vale, ... Elife 8, e42695, 2019 | 102 | 2019 |
Dynamin regulates the dynamics and mechanical strength of the actin cytoskeleton as a multifilament actin-bundling protein R Zhang, DM Lee, JR Jimah, N Gerassimov, C Yang, S Kim, D Luvsanjav, ... Nature cell biology 22 (6), 674-688, 2020 | 89 | 2020 |
Stoichiometry of Nck-dependent actin polymerization in living cells JA Ditlev, PJ Michalski, G Huber, GM Rivera, WA Mohler, LM Loew, ... Journal of Cell Biology 197 (5), 643-658, 2012 | 84 | 2012 |
Coupling of protein condensates to ordered lipid domains determines functional membrane organization HY Wang, SH Chan, S Dey, I Castello-Serrano, MK Rosen, JA Ditlev, ... Science advances 9 (17), eadf6205, 2023 | 79 | 2023 |
An open model of actin dendritic nucleation JA Ditlev, NM Vacanti, IL Novak, LM Loew Biophysical journal 96 (9), 3529-3542, 2009 | 66 | 2009 |
Gene expression profiling of renal cell carcinoma MH Tan, CG Rogers, JT Cooper, JA Ditlev, TJ Maatman, X Yang, ... Clinical cancer research 10 (18), 6315S-6321S, 2004 | 55 | 2004 |
Biomolecular condensates in membrane receptor signaling K Jaqaman, JA Ditlev Current opinion in cell biology 69, 48-54, 2021 | 52 | 2021 |
Membrane-associated phase separation: organization and function emerge from a two-dimensional milieu JA Ditlev Journal of Molecular Cell Biology 13 (4), 319-324, 2021 | 51 | 2021 |
The role of sigma 1 receptor in organization of endoplasmic reticulum signaling microdomains V Zhemkov, JA Ditlev, WR Lee, M Wilson, J Liou, MK Rosen, ... Elife 10, e65192, 2021 | 50 | 2021 |
What are the distinguishing features and size requirements of biomolecular condensates and their implications for RNA-containing condensates? JD Forman-Kay, JA Ditlev, ML Nosella, HO Lee RNA 28 (1), 36-47, 2022 | 39 | 2022 |
Reconstitution of TCR signaling using supported lipid bilayers X Su, JA Ditlev, MK Rosen, RD Vale The Immune Synapse: Methods and Protocols, 65-76, 2017 | 39 | 2017 |
Allosteric Modulation of Grb2 Recruitment to the Intrinsically Disordered Scaffold Protein, LAT, by Remote Site Phosphorylation WYC Huang, JA Ditlev, HK Chiang, MK Rosen, JT Groves Journal of the American Chemical Society 139 (49), 18009-18015, 2017 | 34 | 2017 |
There is more than one way to model an elephant. Experiment-driven modeling of the actin cytoskeleton JA Ditlev, BJ Mayer, LM Loew Biophysical journal 104 (3), 520-532, 2013 | 28 | 2013 |