Fate tracing reveals the pericyte and not epithelial origin of myofibroblasts in kidney fibrosis BD Humphreys, SL Lin, A Kobayashi, TE Hudson, BT Nowlin, ... The American journal of pathology 176 (1), 85-97, 2010 | 1628 | 2010 |
Intrinsic epithelial cells repair the kidney after injury BD Humphreys, MT Valerius, A Kobayashi, JW Mugford, S Soeung, ... Cell stem cell 2 (3), 284-291, 2008 | 1013 | 2008 |
Mechanisms of renal fibrosis BD Humphreys Annual review of physiology 80 (1), 309-326, 2018 | 1011 | 2018 |
Kidney injury molecule–1 is a phosphatidylserine receptor that confers a phagocytic phenotype on epithelial cells T Ichimura, EJP Asseldonk, BD Humphreys, L Gunaratnam, JS Duffield, ... The Journal of clinical investigation 118 (5), 1657-1668, 2008 | 966 | 2008 |
Perivascular Gli1+ progenitors are key contributors to injury-induced organ fibrosis R Kramann, RK Schneider, DP DiRocco, F Machado, S Fleig, PA Bondzie, ... Cell stem cell 16 (1), 51-66, 2015 | 929 | 2015 |
Advantages of single-nucleus over single-cell RNA sequencing of adult kidney: rare cell types and novel cell states revealed in fibrosis H Wu, Y Kirita, EL Donnelly, BD Humphreys Journal of the American Society of Nephrology 30 (1), 23-32, 2019 | 666 | 2019 |
Comparative analysis and refinement of human PSC-derived kidney organoid differentiation with single-cell transcriptomics H Wu, K Uchimura, EL Donnelly, Y Kirita, SA Morris, BD Humphreys Cell stem cell 23 (6), 869-881. e8, 2018 | 557 | 2018 |
Differentiated kidney epithelial cells repair injured proximal tubule T Kusaba, M Lalli, R Kramann, A Kobayashi, BD Humphreys Proceedings of the National Academy of Sciences 111 (4), 1527-1532, 2014 | 523 | 2014 |
Targeted proximal tubule injury triggers interstitial fibrosis and glomerulosclerosis I Grgic, G Campanholle, V Bijol, C Wang, VS Sabbisetti, T Ichimura, ... Kidney international 82 (2), 172-183, 2012 | 508 | 2012 |
Repair of injured proximal tubule does not involve specialized progenitors BD Humphreys, S Czerniak, DP DiRocco, W Hasnain, R Cheema, ... Proceedings of the National Academy of Sciences 108 (22), 9226-9231, 2011 | 451 | 2011 |
Cell profiling of mouse acute kidney injury reveals conserved cellular responses to injury Y Kirita, H Wu, K Uchimura, PC Wilson, BD Humphreys Proceedings of the National Academy of Sciences 117 (27), 15874-15883, 2020 | 440 | 2020 |
The single-cell transcriptomic landscape of early human diabetic nephropathy PC Wilson, H Wu, Y Kirita, K Uchimura, N Ledru, HG Rennke, PA Welling, ... Proceedings of the National Academy of Sciences 116 (39), 19619-19625, 2019 | 436 | 2019 |
Mesenchymal stem cells in fibrotic disease E El Agha, R Kramann, RK Schneider, X Li, W Seeger, BD Humphreys, ... Cell stem cell 21 (2), 166-177, 2017 | 433 | 2017 |
Mesenchymal stem cells in acute kidney injury BD Humphreys, JV Bonventre Annu. Rev. Med. 59 (1), 311-325, 2008 | 429 | 2008 |
Chronic epithelial kidney injury molecule-1 expression causes murine kidney fibrosis BD Humphreys, F Xu, V Sabbisetti, I Grgic, SM Naini, N Wang, G Chen, ... The Journal of clinical investigation 123 (9), 4023-4035, 2013 | 417 | 2013 |
Cediranib, an oral inhibitor of vascular endothelial growth factor receptor kinases, is an active drug in recurrent epithelial ovarian, fallopian tube, and peritoneal cancer UA Matulonis, S Berlin, P Ivy, K Tyburski, C Krasner, C Zarwan, ... Journal of clinical oncology 27 (33), 5601-5606, 2009 | 367 | 2009 |
Single-cell transcriptomics of a human kidney allograft biopsy specimen defines a diverse inflammatory response H Wu, AF Malone, EL Donnelly, Y Kirita, K Uchimura, SM Ramakrishnan, ... Journal of the American Society of Nephrology 29 (8), 2069-2080, 2018 | 359 | 2018 |
Single cell transcriptional and chromatin accessibility profiling redefine cellular heterogeneity in the adult human kidney Y Muto, PC Wilson, N Ledru, H Wu, H Dimke, SS Waikar, BD Humphreys Nature communications 12 (1), 2190, 2021 | 351 | 2021 |
Adventitial MSC-like cells are progenitors of vascular smooth muscle cells and drive vascular calcification in chronic kidney disease R Kramann, C Goettsch, J Wongboonsin, H Iwata, RK Schneider, ... Cell stem cell 19 (5), 628-642, 2016 | 321 | 2016 |
Stress-activated protein kinase/JNK activation and apoptotic induction by the macrophage P2X7 nucleotide receptor BD Humphreys, J Rice, SB Kertesy, GR Dubyak Journal of Biological Chemistry 275 (35), 26792-26798, 2000 | 296 | 2000 |