Orally absorbed cyclic peptides DS Nielsen, NE Shepherd, W Xu, AJ Lucke, MJ Stoermer, DP Fairlie Chemical reviews 117 (12), 8094-8128, 2017 | 403 | 2017 |
Improving on nature: making a cyclic heptapeptide orally bioavailable DS Nielsen, HN Hoang, RJ Lohman, TA Hill, AJ Lucke, DJ Craik, ... Angewandte Chemie International Edition 53 (45), 12059-12063, 2014 | 158 | 2014 |
Potent antimalarial activity of histone deacetylase inhibitor analogues KT Andrews, TN Tran, AJ Lucke, P Kahnberg, GT Le, GM Boyle, ... Antimicrobial agents and chemotherapy 52 (4), 1454-1461, 2008 | 156 | 2008 |
Inhibitors of histone deacetylases in class I and class II suppress human osteoclasts in vitro MD Cantley, DP Fairlie, PM Bartold, KD Rainsford, GT Le, AJ Lucke, ... Journal of cellular physiology 226 (12), 3233-3241, 2011 | 99 | 2011 |
Antimalarial activity of the anticancer histone deacetylase inhibitor SB939 SDM Sumanadasa, CD Goodman, AJ Lucke, T Skinner-Adams, I Sahama, ... Antimicrobial agents and chemotherapy 56 (7), 3849-3856, 2012 | 94 | 2012 |
Histone deacetylase inhibitors and periodontal bone loss MD Cantley, PM Bartold, V Marino, DP Fairlie, GT Le, AJ Lucke, ... Journal of periodontal research 46 (6), 697-703, 2011 | 91 | 2011 |
Comparing sixteen scoring functions for predicting biological activities of ligands for protein targets W Xu, AJ Lucke, DP Fairlie Journal of Molecular Graphics and Modelling 57, 76-88, 2015 | 83 | 2015 |
Design, synthesis, potency, and cytoselectivity of anticancer agents derived by parallel synthesis from α-aminosuberic acid P Kahnberg, AJ Lucke, MP Glenn, GM Boyle, JDA Tyndall, PG Parsons, ... Journal of medicinal chemistry 49 (26), 7611-7622, 2006 | 82 | 2006 |
Flexibility versus rigidity for orally bioavailable cyclic hexapeptides DS Nielsen, RJ Lohman, HN Hoang, TA Hill, A Jones, AJ Lucke, ... ChemBioChem 16 (16), 2289-2293, 2015 | 74 | 2015 |
Cyclic Penta- and Hexaleucine Peptides without N-Methylation Are Orally Absorbed TA Hill, RJ Lohman, HN Hoang, DS Nielsen, CCG Scully, WM Kok, L Liu, ... ACS medicinal chemistry letters 5 (10), 1148-1151, 2014 | 72 | 2014 |
Antimalarial histone deacetylase inhibitors containing cinnamate or NSAID components NC Wheatley, KT Andrews, TL Tran, AJ Lucke, RC Reid, DP Fairlie Bioorganic & medicinal chemistry letters 20 (23), 7080-7084, 2010 | 65 | 2010 |
Thin films of calix-4-resorcinarene deposited by spin coating and Langmuir–Blodgett techniques: determination of film parameters by surface plasmon resonance AK Hassan, AV Nabok, AK Ray, A Lucke, K Smith, CJM Stirling, F Davis Materials Science and Engineering: C 8, 251-255, 1999 | 52 | 1999 |
Designing supramolecular structures from models of cyclic peptide scaffolds with heterocyclic constraints AJ Lucke, JDA Tyndall, Y Singh, DP Fairlie Journal of Molecular Graphics and Modelling 21 (5), 341-355, 2003 | 51 | 2003 |
Amyloid Formation from an α‐Helix Peptide Bundle Is Seeded by 310‐Helix Aggregates Y Singh, PC Sharpe, HN Hoang, AJ Lucke, AW McDowall, SP Bottomley, ... Chemistry–A European Journal 17 (1), 151-160, 2011 | 44 | 2011 |
Inhibitors selective for HDAC6 in enzymes and cells PK Gupta, RC Reid, L Liu, AJ Lucke, SA Broomfield, MR Andrews, ... Bioorganic & medicinal chemistry letters 20 (23), 7067-7070, 2010 | 44 | 2010 |
Structural Mimicry of Two Cytochrome b562 Interhelical Loops Using Macrocycles Constrained by Oxazoles and Thiazoles Y Singh, MJ Stoermer, AJ Lucke, T Guthrie, DP Fairlie Journal of the American Chemical Society 127 (18), 6563-6572, 2005 | 44 | 2005 |
The electrochemistry of the ferri/ferrocyanide couple at a calix [4] resorcinarenetetrathiol-modified gold electrode as a study of novel electrode modifying coatings for use … SD Collyer, F Davis, A Lucke, CJM Stirling, SPJ Higson Journal of Electroanalytical Chemistry 549, 119-127, 2003 | 43 | 2003 |
Order and Structure in Langmuir− Blodgett Mono-and Multilayers of Resorcarenes F Davis, AJ Lucke, KA Smith, CJM Stirling Langmuir 14 (15), 4180-4185, 1998 | 35 | 1998 |
Regioselective synthesis of antiparallel loops on a macrocyclic scaffold constrained by oxazoles and thiazoles Y Singh, MJ Stoermer, AJ Lucke, MP Glenn, DP Fairlie Organic Letters 4 (20), 3367-3370, 2002 | 33 | 2002 |
Identification of brain metastasis genes and therapeutic evaluation of histone deacetylase inhibitors in a clinically relevant model of breast cancer brain metastasis SH Kim, RP Redvers, LH Chi, X Ling, AJ Lucke, RC Reid, DP Fairlie, ... Disease models & mechanisms 11 (7), DMM034850, 2018 | 31 | 2018 |