| Ca2+ signaling in astrocytes from Ip3r2−/− mice in brain slices and during startle responses in vivo R Srinivasan, BS Huang, S Venugopal, AD Johnston, H Chai, H Zeng, ... Nature neuroscience 18 (5), 708-717, 2015 | 546 | 2015 |
| New transgenic mouse lines for selectively targeting astrocytes and studying calcium signals in astrocyte processes in situ and in vivo R Srinivasan, TY Lu, H Chai, J Xu, BS Huang, P Golshani, G Coppola, ... Neuron 92 (6), 1181-1195, 2016 | 427 | 2016 |
| Nicotine is a selective pharmacological chaperone of acetylcholine receptor number and stoichiometry. Implications for drug discovery HA Lester, C Xiao, R Srinivasan, CD Son, J Miwa, R Pantoja, ... The AAPS journal 11, 167-177, 2009 | 189 | 2009 |
| Nicotine up-regulates α4β2 nicotinic receptors and ER exit sites via stoichiometry-dependent chaperoning R Srinivasan, R Pantoja, FJ Moss, EDW Mackey, CD Son, J Miwa, ... Journal of General Physiology 137 (1), 59-79, 2011 | 188 | 2011 |
| Nicotine exploits a COPI-mediated process for chaperone-mediated up-regulation of its receptors BJ Henderson, R Srinivasan, WA Nichols, CN Dilworth, DF Gutierrez, ... Journal of General Physiology 143 (1), 51-66, 2014 | 81 | 2014 |
| Live-Cell Imaging of Single Receptor Composition Using Zero-Mode Waveguide Nanostructures C Richards, L Khai, R Srinivasan, S Turner, D Dougherty, J Korlach, ... Nano Letters, 2012 | 81 | 2012 |
| α7β2 nicotinic acetylcholine receptors assemble, function, and are activated primarily via their α7-α7 interfaces TA Murray, D Bertrand, RL Papke, AA George, R Pantoja, R Srinivasan, ... Molecular pharmacology 81 (2), 175-188, 2012 | 78 | 2012 |
| Pharmacological Chaperoning of Nicotinic Acetylcholine Receptors Reduces the ER Stress Response R Srinivasan, CI Richards, C Xiao, D Rhee, R Pantoja, DA Dougherty, ... Molecular Pharmacology, 2012 | 75 | 2012 |
| Pharmacological chaperoning of nAChRs: A therapeutic target for Parkinson's disease R Srinivasan, BJ Henderson, HA Lester, CI Richards Pharmacological Research, 2014 | 69 | 2014 |
| Trafficking of α4* nicotinic receptors revealed by superecliptic phluorin: effects of a β4 amyotrophic lateral sclerosis-associated mutation and chronic exposure to nicotine CI Richards, R Srinivasan, C Xiao, EDW Mackey, JM Miwa, HA Lester Journal of Biological Chemistry 286 (36), 31241-31249, 2011 | 68 | 2011 |
| Engineering an endomorphin-2 gene for use in neuropathic pain therapy D Wolfe, S Hao, J Hu, R Srinivasan, J Goss, M Mata, DJ Fink, JC Glorioso Pain 133 (1), 29-38, 2007 | 68 | 2007 |
| Smoking-relevant nicotine concentration attenuates the unfolded protein response in dopaminergic neurons R Srinivasan, BM Henley, BJ Henderson, T Indersmitten, BN Cohen, ... Journal of Neuroscience 36 (1), 65-79, 2016 | 65 | 2016 |
| Psychiatric Drugs Bind to Classical Targets Within Early Exocytotic Pathways: Therapeutic Effects HA Lester, JM Miwa, R Srinivasan Biological Psychiatry, 2012 | 59 | 2012 |
| Protein kinase C epsilon contributes to basal and sensitizing responses of TRPV1 to capsaicin in rat dorsal root ganglion neurons R Srinivasan, D Wolfe, J Goss, S Watkins, WC De Groat, A Sculptoreanu, ... European Journal of Neuroscience 28 (7), 1241-1254, 2008 | 57 | 2008 |
| Imaging P2X4 receptor subcellular distribution, trafficking, and regulation using P2X4-pHluorin J Xu, H Chai, K Ehinger, TM Egan, R Srinivasan, M Frick, BS Khakh Journal of General Physiology 144 (1), 81-104, 2014 | 50 | 2014 |
| Characterizing functional α6β2 nicotinic acetylcholine receptors in vitro: mutant β2 subunits improve membrane expression, and fluorescent proteins reveal responsive cells. C Xiao, R Srinivasan, RM Drenan, ED Mackey, JM McIntosh, HA Lester Biochemical pharmacology 82 (8), 852, 2011 | 44 | 2011 |
| Transcriptional regulation by nicotine in dopaminergic neurons BM Henley, BA Williams, R Srinivasan, BN Cohen, C Xiao, EDW Mackey, ... Biochemical pharmacology 86 (8), 1074-1083, 2013 | 33 | 2013 |
| Förster Resonance Energy Transfer (FRET) Correlates of Altered Subunit Stoichiometry in Cys-Loop Receptors, Exemplified by Nicotinic α4β2 R Srinivasan, CI Richards, C Dilworth, FJ Moss, DA Dougherty, HA Lester International Journal of Molecular Sciences 13 (8), 10022-10040, 2012 | 29 | 2012 |
| Adeno-associated virus expression of α-synuclein as a tool to model Parkinson’s disease: current understanding and knowledge gaps TE Huntington, R Srinivasan Aging and disease 12 (4), 1120, 2021 | 27 | 2021 |
| Astrocytic mitochondria in adult mouse brain slices show spontaneous calcium influx events with unique properties TE Huntington, R Srinivasan Cell Calcium 96, 102383, 2021 | 27 | 2021 |
Henry A. LesterProfessor of Biology and Biological Engineering, CaltechEmail verificata su caltech.edu
