| Targeted DNA demethylation in vivo using dCas9–peptide repeat and scFv–TET1 catalytic domain fusions S Morita, H Noguchi, T Horii, K Nakabayashi, M Kimura, K Okamura, ... Nature biotechnology 34 (10), 1060-1065, 2016 | 516 | 2016 |
| A genomic scanning method for higher organisms using restriction sites as landmarks. I Hatada, Y Hayashizaki, S Hirotsune, H Komatsubara, T Mukai Proceedings of the National Academy of Sciences 88 (21), 9523-9527, 1991 | 467 | 1991 |
| An imprinted gene p57KIP2 is mutated in Beckwith–Wiedemann syndrome I Hatada, H Ohashi, Y Fukushima, Y Kaneko, M Inoue, Y Komoto, ... Nature genetics 14 (2), 171-173, 1996 | 459 | 1996 |
| Structure and engineering of Francisella novicida Cas9 H Hirano, JS Gootenberg, T Horii, OO Abudayyeh, M Kimura, PD Hsu, ... Cell 164 (5), 950-961, 2016 | 416 | 2016 |
| Genomic imprinting of p57KIP2, a cyclin–dependent kinase inhibitor, in mouse I Hatada, T Mukai Nature genetics 11 (2), 204-206, 1995 | 367 | 1995 |
| Validation of microinjection methods for generating knockout mice by CRISPR/Cas-mediated genome engineering T Horii, Y Arai, M Yamazaki, S Morita, M Kimura, M Itoh, Y Abe, I Hatada Scientific reports 4 (1), 4513, 2014 | 224 | 2014 |
| One Argonaute family member, Eif2c2 (Ago2), is essential for development and appears not to be involved in DNA methylation S Morita, T Horii, M Kimura, Y Goto, T Ochiya, I Hatada Genomics 89 (6), 687-696, 2007 | 222 | 2007 |
| Analysis of germline CDKN1C (p57KIP2) mutations in familial and sporadic Beckwith-Wiedemann syndrome (BWS) provides a novel genotype-phenotype correlation WWK Lam, I Hatada, S Ohishi, T Mukai, JA Joyce, TRP Cole, D Donnai, ... Journal of medical genetics 36 (7), 518-523, 1999 | 216 | 1999 |
| Restriction landmark genomic scanning method and its various applications Y Hayashizaki, S Hirotsune, Y Okazaki, I Hatada, H Shibata, J Kawai, ... Electrophoresis 14 (1), 251-258, 1993 | 207 | 1993 |
| 5-Hydroxymethylcytosine marks sites of DNA damage and promotes genome stability GR Kafer, X Li, T Horii, I Suetake, S Tajima, I Hatada, PM Carlton Cell reports 14 (6), 1283-1292, 2016 | 188 | 2016 |
| DNA Methylation Is Linked to Deacetylation of Histone H3, but Not H4, on the Imprinted Genes Snrpnand U2af1-rs1 RI Gregory, TE Randall, CA Johnson, S Khosla, I Hatada, LP O'Neill, ... Molecular and cellular biology 21 (16), 5426-5436, 2001 | 179 | 2001 |
| Genome-wide profiling of promoter methylation in human I Hatada, M Fukasawa, M Kimura, S Morita, K Yamada, T Yoshikawa, ... Oncogene 25 (21), 3059-3064, 2006 | 174 | 2006 |
| miR-29 represses the activities of DNA methyltransferases and DNA demethylases S Morita, T Horii, M Kimura, T Ochiya, S Tajima, I Hatada International journal of molecular sciences 14 (7), 14647-14658, 2013 | 170 | 2013 |
| MeCP2-dependent repression of an imprinted miR-184 released by depolarization T Nomura, M Kimura, T Horii, S Morita, H Soejima, S Kudo, I Hatada Human molecular genetics 17 (8), 1192-1199, 2008 | 170 | 2008 |
| Genomic Imprinting of Human p57 KIP2 and Its Reduced Expression in Wilms' Tumors I Hatada, J Inazawa, T Abe, M Nakayama, Y Kaneko, Y Jinno, N Niikawa, ... Human molecular genetics 5 (6), 783-788, 1996 | 169 | 1996 |
| Microarray analysis of promoter methylation in lung cancers M Fukasawa, M Kimura, S Morita, K Matsubara, S Yamanaka, C Endo, ... Journal of human genetics 51 (4), 368-374, 2006 | 152 | 2006 |
| miR‐148a plays a pivotal role in the liver by promoting the hepatospecific phenotype and suppressing the invasiveness of transformed cells L Gailhouste, L Gomez‐Santos, K Hagiwara, I Hatada, N Kitagawa, ... Hepatology 58 (3), 1153-1165, 2013 | 150 | 2013 |
| Linear ubiquitination is involved in the pathogenesis of optineurin-associated amyotrophic lateral sclerosis S Nakazawa, D Oikawa, R Ishii, T Ayaki, H Takahashi, H Takeda, ... Nature communications 7 (1), 12547, 2016 | 146 | 2016 |
| Generation of an ICF syndrome model by efficient genome editing of human induced pluripotent stem cells using the CRISPR system T Horii, D Tamura, S Morita, M Kimura, I Hatada International journal of molecular sciences 14 (10), 19774-19781, 2013 | 144 | 2013 |
| Mouse U2af1-rs1 Is a Neomorphic Imprinted Gene A Nabetani, I Hatada, H Morisaki, M Oshimura, T Mukai Molecular and cellular biology 17 (2), 789-798, 1997 | 122 | 1997 |
Shoji TajimaInstitute for Protein Reseach, Osaka UniversityEmail verificata su protein.osaka-u.ac.jp