Developing context appropriate toxicity testing approaches using new alternative methods (NAMs) ME Andersen, PD McMullen, MB Phillips, M Yoon, SN Pendse, ... ALTEX-Alternatives to animal experimentation 36 (4), 523-534, 2019 | 57 | 2019 |
Development and application of a life-stage physiologically based pharmacokinetic (PBPK) model to the assessment of internal dose of pyrethroids in humans P Mallick, M Moreau, G Song, AY Efremenko, SN Pendse, MR Creek, ... Toxicological Sciences 173 (1), 86-99, 2020 | 44 | 2020 |
Hexabromocyclododecane (HBCD): A case study applying tiered testing for human health risk assessment AM Gannon, M Moreau, R Farmahin, RS Thomas, TS Barton-Maclaren, ... Food and Chemical Toxicology 131, 110581, 2019 | 30 | 2019 |
Using exposure prediction tools to link exposure and dosimetry for risk-based decisions: A case study with phthalates M Moreau, J Leonard, KA Phillips, J Campbell, SN Pendse, C Nicolas, ... Chemosphere 184, 1194-1201, 2017 | 28 | 2017 |
Evaluation of Age-Related Pyrethroid Pharmacokinetic Differences in Rats: Physiologically-Based Pharmacokinetic Model Development Using In Vitro Data and In Vitro to … G Song, M Moreau, A Efremenko, BG Lake, H Wu, JV Bruckner, CA White, ... Toxicological Sciences 169 (2), 365-379, 2019 | 27 | 2019 |
Metabolism of deltamethrin and cis- and trans-permethrin by human expressed cytochrome P450 and carboxylesterase enzymes. LBG Hedges L, Brown S, MacLeod AK, Vardy A, Doyle E, Song G, Moreau M, Yoon ... Xenobiotica 21, 1-22, 2018 | 25* | 2018 |
Population Life-course exposure to health effects model (PLETHEM): An R package for PBPK modeling SN Pendse, A Efremenko, CE Hack, M Moreau, P Mallick, M Dzierlenga, ... Computational Toxicology 13, 100115, 2020 | 22 | 2020 |
The role of fit-for-purpose assays within tiered testing approaches: a case study evaluating prioritized estrogen-active compounds in an in vitro human uterotrophic assay T Beames, M Moreau, LA Roberts, K Mansouri, S Haider, M Smeltz, ... Toxicology and Applied Pharmacology 387, 114774, 2020 | 16 | 2020 |
Comparison of the kinetics of various biomarkers of benzo[a]pyrene exposure following different routes of entry in rats M Moreau, M Bouchard Journal of Applied Toxicology 35 (7), 781-790, 2015 | 16 | 2015 |
Quantitative bias analysis of the association between subclinical thyroid disease and two perfluoroalkyl substances in a single study MW Dzierlenga, M Moreau, G Song, P Mallick, PL Ward, JL Campbell, ... Environmental research 182, 109017, 2020 | 15 | 2020 |
Evaluating hexabromocyclododecane (HBCD) toxicokinetics in humans and rodents by physiologically based pharmacokinetic modeling M Moreau, A Nong Food and Chemical Toxicology 133, 110785, 2019 | 15 | 2019 |
Effects of intravenous benzo [a] pyrene dose administration on levels of exposure biomarkers, DNA adducts, and gene expression in rats M Moreau, N Ouellet, P Ayotte, M Bouchard Journal of Toxicology and Environmental Health, Part A 78 (3), 166-184, 2015 | 15 | 2015 |
NAM-based prediction of point-of-contact toxicity in the lung: A case example with 1, 3-dichloropropene M Moreau, J Fisher, ME Andersen, A Barnwell, S Corzine, A Ranade, ... Toxicology 481, 153340, 2022 | 14 | 2022 |
Considerations for Improving Metabolism Predictions for In Vitro to In Vivo Extrapolation M Moreau, P Mallick, M Smeltz, S Haider, CI Nicolas, SN Pendse, ... Frontiers in Toxicology 4, 894569, 2022 | 11 | 2022 |
Biological system considerations for application of toxicogenomics in next-generation risk assessment and predictive toxicology MB Black, A Stern, A Efremenko, P Mallick, M Moreau, JK Hartman, ... Toxicology in Vitro 80, 105311, 2022 | 10 | 2022 |
Metabolism of bifenthrin, β-cyfluthrin, λ-cyhalothrin, cyphenothrin and esfenvalerate by rat and human cytochrome P450 and carboxylesterase enzymes L Hedges, S Brown, AK MacLeod, M Moreau, M Yoon, MR Creek, ... Xenobiotica 50 (12), 1434-1442, 2020 | 10 | 2020 |
Reverse dosimetry modeling of toluene exposure concentrations based on biomonitoring levels from the Canadian health measures survey. HS Tohon H, Nong A, Moreau M, Valcke M J Toxicol Environ Health A, 2018 | 10 | 2018 |
Physiologically based pharmacokinetic modeling in risk assessment: case study with pyrethroids P Mallick, G Song, AY Efremenko, SN Pendse, MR Creek, TG Osimitz, ... Toxicological Sciences 176 (2), 460-469, 2020 | 9 | 2020 |
Kinetics of diol and hydroxybenzo [a] pyrene metabolites in relation to DNA adduct formation and gene expression in rats M Moreau, P Ayotte, M Bouchard Journal of Toxicology and Environmental Health, Part A 78 (12), 725-746, 2015 | 8 | 2015 |
Animal-free assessment of developmental toxicity: Combining PBPK modeling with the ReproTracker assay M Moreau, A Jamalpoor, JC Hall, J Fisher, S Hartvelt, G Hendriks, A Nong Toxicology 500, 153684, 2023 | 5 | 2023 |