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Mark Behlke
Mark Behlke
Integrated DNA Technologies
Email verificata su idtdna.com
Titolo
Citata da
Citata da
Anno
Synthetic dsRNA Dicer substrates enhance RNAi potency and efficacy
DH Kim, MA Behlke, SD Rose, MS Chang, S Choi, JJ Rossi
Nature biotechnology 23 (2), 222-226, 2005
12732005
Identification of preexisting adaptive immunity to Cas9 proteins in humans
CT Charlesworth, PS Deshpande, DP Dever, J Camarena, VT Lemgart, ...
Nature medicine 25 (2), 249-254, 2019
10622019
A high-fidelity Cas9 mutant delivered as a ribonucleoprotein complex enables efficient gene editing in human hematopoietic stem and progenitor cells
CA Vakulskas, DP Dever, GR Rettig, R Turk, AM Jacobi, MA Collingwood, ...
Nature medicine 24 (8), 1216-1224, 2018
8142018
Progress towards in vivo use of siRNAs
MA Behlke
Molecular Therapy 13 (4), 644-670, 2006
7572006
Chemical Modification of siRNAs for In Vivo Use
MA Behlke
Oligonucleotides 18 (4), 305-320, 2008
6432008
Chemical modification and design of anti-miRNA oligonucleotides
KA Lennox, MA Behlke
Gene therapy 18 (12), 1111-1120, 2011
5572011
Functional polarity is introduced by Dicer processing of short substrate RNAs
SD Rose, DH Kim, M Amarzguioui, JD Heidel, MA Collingwood, ME Davis, ...
Nucleic acids research 33 (13), 4140-4156, 2005
5412005
A structural basis for discriminating between self and nonself double-stranded RNAs in mammalian cells
JT Marques, T Devosse, D Wang, M Zamanian-Daryoush, P Serbinowski, ...
Nature biotechnology 24 (5), 559-565, 2006
5212006
Analysis of microRNA turnover in mammalian cells following Dicer1 ablation
MP Gantier, CE McCoy, I Rusinova, D Saulep, D Wang, D Xu, AT Irving, ...
Nucleic acids research 39 (13), 5692-5703, 2011
5172011
Easi-CRISPR: a robust method for one-step generation of mice carrying conditional and insertion alleles using long ssDNA donors and CRISPR ribonucleoproteins
RM Quadros, H Miura, DW Harms, H Akatsuka, T Sato, T Aida, R Redder, ...
Genome biology 18, 1-15, 2017
4972017
Cellular localization of long non-coding RNAs affects silencing by RNAi more than by antisense oligonucleotides
KA Lennox, MA Behlke
Nucleic acids research 44 (2), 863-877, 2016
4662016
Predicting stability of DNA duplexes in solutions containing magnesium and monovalent cations
R Owczarzy, BG Moreira, Y You, MA Behlke, JA Walder
Biochemistry 47 (19), 5336-5353, 2008
4522008
Effects of sodium ions on DNA duplex oligomers: improved predictions of melting temperatures
R Owczarzy, Y You, BG Moreira, JA Manthey, L Huang, MA Behlke, ...
Biochemistry 43 (12), 3537-3554, 2004
4462004
CRISPR-Cas9 genome editing using targeted lipid nanoparticles for cancer therapy
D Rosenblum, A Gutkin, R Kedmi, S Ramishetti, N Veiga, AM Jacobi, ...
Science advances 6 (47), eabc9450, 2020
4322020
Murine T-cell receptor mutants with deletions of beta-chain variable region genes.
MA Behlke, HS Chou, K Huppi, DY Loh
Proceedings of the National Academy of Sciences 83 (3), 767-771, 1986
4261986
Design of LNA probes that improve mismatch discrimination
Y You, BG Moreira, MA Behlke, R Owczarzy
Nucleic acids research 34 (8), e60-e60, 2006
4032006
Hybridization kinetics and thermodynamics of molecular beacons
A Tsourkas, MA Behlke, SD Rose, G Bao
Nucleic acids research 31 (4), 1319-1330, 2003
3892003
Chitosan/siRNA nanoparticle–mediated TNF-α knockdown in peritoneal macrophages for anti-inflammatory treatment in a murine arthritis model
KA Howard, SR Paludan, MA Behlke, F Besenbacher, B Deleuran, ...
Molecular therapy 17 (1), 162-168, 2009
3552009
miRNAs control insulin content in pancreatic β‐cells via downregulation of transcriptional repressors
T Melkman‐Zehavi, R Oren, S Kredo‐Russo, T Shapira, AD Mandelbaum, ...
The EMBO journal 30 (5), 835-845, 2011
3512011
A modular platform for targeted RNAi therapeutics
R Kedmi, N Veiga, S Ramishetti, M Goldsmith, D Rosenblum, N Dammes, ...
Nature nanotechnology 13 (3), 214-219, 2018
2932018
Il sistema al momento non può eseguire l'operazione. Riprova più tardi.
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