| Evolutionary classification of CRISPR–Cas systems: a burst of class 2 and derived variants KS Makarova, YI Wolf, J Iranzo, SA Shmakov, OS Alkhnbashi, SJJ Brouns, ... Nature Reviews Microbiology 18 (2), 67-83, 2020 | 2219 | 2020 |
| Origins and evolution of the global RNA virome YI Wolf, D Kazlauskas, J Iranzo, A Lucía-Sanz, JH Kuhn, M Krupovic, ... MBio 9 (6), 10.1128/mbio. 02329-18, 2018 | 446 | 2018 |
| Viruses of archaea: structural, functional, environmental and evolutionary genomics M Krupovic, V Cvirkaite-Krupovic, J Iranzo, D Prangishvili, EV Koonin Virus research 244, 181-193, 2018 | 215 | 2018 |
| The enigmatic archaeal virosphere D Prangishvili, DH Bamford, P Forterre, J Iranzo, EV Koonin, M Krupovic Nature Reviews Microbiology 15 (12), 724-739, 2017 | 196 | 2017 |
| The double-stranded DNA virosphere as a modular hierarchical network of gene sharing J Iranzo, M Krupovic, EV Koonin MBio 7 (4), 10.1128/mbio. 00978-16, 2016 | 172 | 2016 |
| Cancer-mutation network and the number and specificity of driver mutations J Iranzo, I Martincorena, EV Koonin Proceedings of the National Academy of Sciences 115 (26), E6010-E6019, 2018 | 150 | 2018 |
| Evolutionary dynamics of the prokaryotic adaptive immunity system CRISPR-Cas in an explicit ecological context J Iranzo, AE Lobkovsky, YI Wolf, EV Koonin Journal of bacteriology 195 (17), 3834-3844, 2013 | 107 | 2013 |
| Bipartite network analysis of the archaeal virosphere: evolutionary connections between viruses and capsidless mobile elements J Iranzo, EV Koonin, D Prangishvili, M Krupovic Journal of virology 90 (24), 11043-11055, 2016 | 100 | 2016 |
| Inevitability of genetic parasites J Iranzo, P Puigbò, AE Lobkovsky, YI Wolf, EV Koonin Genome biology and evolution 8 (9), 2856-2869, 2016 | 97 | 2016 |
| The ultimatum game in complex networks R Sinatra, J Iranzo, J Gomez-Gardenes, LM Floria, V Latora, Y Moreno Journal of Statistical Mechanics: Theory and Experiment 2009 (09), P09012, 2009 | 94 | 2009 |
| Gene gain and loss push prokaryotes beyond the homologous recombination barrier and accelerate genome sequence divergence J Iranzo, YI Wolf, EV Koonin, I Sela Nature communications 10 (1), 5376, 2019 | 81 | 2019 |
| Evolutionary dynamics of genome segmentation in multipartite viruses J Iranzo, SC Manrubia Proceedings of the Royal Society B: Biological Sciences 279 (1743), 3812-3819, 2012 | 73 | 2012 |
| A network analysis of the human T-cell activation gene network identifies JAGGED1 as a therapeutic target for autoimmune diseases R Palacios, J Goni, I Martinez-Forero, J Iranzo, J Sepulcre, I Melero, ... PLoS One 2 (11), e1222, 2007 | 71 | 2007 |
| The spatial Ultimatum game revisited J Iranzo, J Román, A Sánchez Journal of Theoretical Biology, 2011 | 69 | 2011 |
| Myosin-driven transport network in plants EG Kurth, VV Peremyslov, HL Turner, KS Makarova, J Iranzo, ... Proceedings of the National Academy of Sciences 114 (8), E1385-E1394, 2017 | 66 | 2017 |
| Disentangling the effects of selection and loss bias on gene dynamics J Iranzo, JA Cuesta, S Manrubia, MI Katsnelson, EV Koonin Proceedings of the National Academy of Sciences 114 (28), E5616-E5624, 2017 | 54 | 2017 |
| The impact of quasispecies dynamics on the use of therapeutics C Perales, J Iranzo, SC Manrubia, E Domingo Trends in microbiology 20 (12), 595-603, 2012 | 52 | 2012 |
| Two RNase H2 mutants with differential rNMP processing activity reveal a threshold of ribonucleotide tolerance for embryonic development R Uehara, SM Cerritelli, N Hasin, K Sakhuja, M London, J Iranzo, H Chon, ... Cell reports 25 (5), 1135-1145. e5, 2018 | 50 | 2018 |
| Virus-host arms race at the joint origin of multicellularity and programmed cell death J Iranzo, AE Lobkovsky, YI Wolf, EV Koonin Cell cycle 13 (19), 3083-3088, 2014 | 50 | 2014 |
| Genomes of the “Candidatus Actinomarinales” Order: Highly Streamlined Marine Epipelagic Actinobacteria M López-Pérez, JM Haro-Moreno, J Iranzo, F Rodriguez-Valera Msystems 5 (6), 10.1128/msystems. 01041-20, 2020 | 46 | 2020 |
Eugene KooninSenior Investigator, NCBI, NIHEmail verificata su ncbi.nlm.nih.gov