Chitosan for gene delivery and orthopedic tissue engineering applications R Raftery, FJ O'Brien, SA Cryan Molecules 18 (5), 5611-5647, 2013 | 224 | 2013 |
Multifunctional biomaterials from the sea: Assessing the effects of chitosan incorporation into collagen scaffolds on mechanical and biological functionality RM Raftery, B Woods, ALP Marques, J Moreira-Silva, TH Silva, SA Cryan, ... Acta Biomaterialia 43, 160-169, 2016 | 168 | 2016 |
Translating the role of osteogenic-angiogenic coupling in bone formation: Highly efficient chitosan-pDNA activated scaffolds can accelerate bone regeneration in critical-sized … RM Raftery, IM Castaño, G Chen, B Cavanagh, B Quinn, CM Curtin, ... Biomaterials 149, 116-127, 2017 | 135 | 2017 |
Development of a Gene-Activated Scaffold Platform for Tissue Engineering Applications Using Chitosan-pDNA Nanoparticles on Collagen-Based Scaffolds RM Raftery, EG Tierney, CM Curtin, SA Cryan, FJ O’Brien Journal of Controlled Release, 2015 | 123 | 2015 |
Delivering Nucleic‐Acid Based Nanomedicines on Biomaterial Scaffolds for Orthopedic Tissue Repair: Challenges, Progress and Future Perspectives RM Raftery, DP Walsh, IM Castaño, A Heise, GP Duffy, SA Cryan, ... Advanced Materials 28 (27), 5447-5469, 2016 | 117 | 2016 |
Investigating the interplay between substrate stiffness and ligand chemistry in directing mesenchymal stem cell differentiation within 3D macro-porous substrates MG Haugh, TJ Vaughan, CM Madl, RM Raftery, LM McNamara, ... Biomaterials 171, 23-33, 2018 | 91 | 2018 |
Delivery of the improved BMP-2-Advanced plasmid DNA within a gene-activated scaffold accelerates mesenchymal stem cell osteogenesis and critical size defect repair RM Raftery, I Mencía-Castaño, S Sperger, G Chen, B Cavanagh, ... Journal of Controlled Release 283, 20-31, 2018 | 84 | 2018 |
Highly versatile cell-penetrating peptide loaded scaffold for efficient and localised gene delivery to multiple cell types: From development to application in tissue engineering RM Raftery, DP Walsh, LB Ferreras, IM Castaño, G Chen, M LeMoine, ... Biomaterials 216, 119277, 2019 | 68 | 2019 |
Rapid healing of a critical‐sized bone defect using a collagen‐hydroxyapatite scaffold to facilitate low dose, combinatorial growth factor delivery DP Walsh, RM Raftery, G Chen, A Heise, FJ O'Brien, SA Cryan Journal of tissue engineering and regenerative medicine 13 (10), 1843-1853, 2019 | 61 | 2019 |
pro-angiogenic impact of Sdf-1α gene-activated collagen-based scaffolds in stem cell driven angiogenesis AL Laiva, RM Raftery, MB Keogh, FJ O'brien International journal of pharmaceutics 544 (2), 372-379, 2018 | 57 | 2018 |
Bioinspired Star-Shaped Poly(l-lysine) Polypeptides: Efficient Polymeric Nanocarriers for the Delivery of DNA to Mesenchymal Stem Cells DP Walsh, RD Murphy, A Panarella, RM Raftery, B Cavanagh, ... Molecular pharmaceutics 15 (5), 1878-1891, 2018 | 54 | 2018 |
In vitro efficacy of a gene-activated nerve guidance conduit incorporating non-viral PEI-pDNA nanoparticles carrying genes encoding for NGF, GDNF and c-Jun WA Lackington, RM Raftery, FJ O'Brien Acta biomaterialia 75, 115-128, 2018 | 51 | 2018 |
Rapid Bone Repair with the Recruitment of CD206+ M2-like Macrophages Using Non-Viral Scaffold-Mediated miR-133a Inhibition of Host Cells IM Castaño, RM Raftery, G Chen, B Cavanagh, B Quinn, GP Duffy, ... Acta Biomaterialia, 2020 | 49 | 2020 |
Scaffold‐Based Delivery of Nucleic Acid Therapeutics for Enhanced Bone and Cartilage Repair DC Kelly, RM Raftery, CM Curtin, CM O’Driscoll, FJ O’Brien Journal of Orthopaedic Research® 37 (8), 1671-1680, 2019 | 47 | 2019 |
Activation of the SOX‐5, SOX‐6, and SOX‐9 Trio of Transcription Factors Using a Gene‐Activated Scaffold Stimulates Mesenchymal Stromal Cell Chondrogenesis and Inhibits … RM Raftery, AG Gonzalez Vazquez, G Chen, FJ O'Brien Advanced Healthcare Materials 9 (10), 1901827, 2020 | 42 | 2020 |
Transfection of autologous host cells in vivo using gene activated collagen scaffolds incorporating star-polypeptides DP Walsh, RM Raftery, IM Castaño, R Murphy, B Cavanagh, A Heise, ... Journal of Controlled Release 304, 191-203, 2019 | 39 | 2019 |
Nanoparticle-mediated siRNA delivery assessed in a 3D co-culture model simulating prostate cancer bone metastasis KA Fitzgerald, J Guo, RM Raftery, IM Castaño, CM Curtin, M Gooding, ... International Journal of Pharmaceutics 511 (2), 1058-1069, 2016 | 37 | 2016 |
Gene activated scaffolds incorporating star-shaped polypeptide-pDNA nanomedicines accelerate bone tissue regeneration in vivo DP Walsh, RM Raftery, R Murphy, G Chen, A Heise, FJ O'Brien, SA Cryan Biomaterials Science 9 (14), 4984-4999, 2021 | 29 | 2021 |
Mechanobiology-informed regenerative medicine: Dose-controlled release of placental growth factor from a functionalized collagen-based scaffold promotes angiogenesis and … EJ Sheehy, GJ Miller, I Amado, RM Raftery, G Chen, K Cortright, ... Journal of Controlled Release 334, 96-105, 2021 | 25 | 2021 |
Dual scaffold delivery of miR-210 mimic and miR-16 inhibitor enhances angiogenesis and osteogenesis to accelerate bone healing IM Castaño, RM Raftery, G Chen, B Cavanagh, B Quinn, GP Duffy, ... Acta Biomaterialia 172, 480-493, 2023 | 19 | 2023 |