| Gut microbiota regulate motor deficits and neuroinflammation in a model of Parkinson’s disease TR Sampson, JW Debelius, T Thron, S Janssen, GG Shastri, ZE Ilhan, ... Cell 167 (6), 1469-1480. e12, 2016 | 3501 | 2016 |
| LRP1 is a master regulator of tau uptake and spread JN Rauch, G Luna, E Guzman, M Audouard, C Challis, YE Sibih, ... Nature 580 (7803), 381-385, 2020 | 495 | 2020 |
| A gut bacterial amyloid promotes α-synuclein aggregation and motor impairment in mice TR Sampson, C Challis, N Jain, A Moiseyenko, MS Ladinsky, GG Shastri, ... elife 9, e53111, 2020 | 410 | 2020 |
| Gut-seeded α-synuclein fibrils promote gut dysfunction and brain pathology specifically in aged mice C Challis, A Hori, TR Sampson, BB Yoo, RC Challis, AM Hamilton, ... Nature Neuroscience 23 (3), 327-336, 2020 | 360 | 2020 |
| Systemic AAV vectors for widespread and targeted gene delivery in rodents RC Challis, S Ravindra Kumar, KY Chan, C Challis, K Beadle, MJ Jang, ... Nature protocols 14 (2), 379-414, 2019 | 352 | 2019 |
| Raphe GABAergic neurons mediate the acquisition of avoidance after social defeat C Challis, J Boulden, A Veerakumar, J Espallergues, FM Vassoler, ... Journal of Neuroscience 33 (35), 13978-13988, 2013 | 229 | 2013 |
| Optogenetic modulation of descending prefrontocortical inputs to the dorsal raphe bidirectionally bias socioaffective choices after social defeat C Challis, SG Beck, O Berton Frontiers in behavioral neuroscience 8, 43, 2014 | 161 | 2014 |
| HDAC6 regulates glucocorticoid receptor signaling in serotonin pathways with critical impact on stress resilience J Espallergues, SL Teegarden, A Veerakumar, J Boulden, C Challis, ... Journal of Neuroscience 32 (13), 4400-4416, 2012 | 151 | 2012 |
| Antidepressant-like effects of cortical deep brain stimulation coincide with pro-neuroplastic adaptations of serotonin systems A Veerakumar, C Challis, P Gupta, J Da, A Upadhyay, SG Beck, O Berton Biological psychiatry 76 (3), 203-212, 2014 | 114 | 2014 |
| Top-down control of serotonin systems by the prefrontal cortex: a path toward restored socioemotional function in depression C Challis, O Berton ACS chemical neuroscience 6 (7), 1040-1054, 2015 | 107 | 2015 |
| Enhancement of stress resilience through histone deacetylase 6–mediated regulation of glucocorticoid receptor chaperone dynamics J Jochems, SL Teegarden, Y Chen, J Boulden, C Challis, GA Ben-Dor, ... Biological psychiatry 77 (4), 345-355, 2015 | 63 | 2015 |
| Widespread and targeted gene expression by systemic AAV vectors: Production, purification, and administration RC Challis, SR Kumar, KY Chan, C Challis, MJ Jang, PS Rajendran, ... BioRXiv, 246405, 2018 | 21 | 2018 |
| Q&A: How can advances in tissue clearing and optogenetics contribute to our understanding of normal and diseased biology? A Greenbaum, MJ Jang, C Challis, V Gradinaru BMC biology 15, 1-10, 2017 | 14 | 2017 |
| Peripheral neuronal activation shapes the microbiome and alters gut physiology JA Griffiths, BB Yoo, P Thuy-Boun, VJ Cantu, KC Weldon, C Challis, ... Cell reports 43 (4), 2024 | 7 | 2024 |
| Targeted neuronal activation of the gastrointestinal tract shapes the environment of the gut in mice BB Yoo, JA Griffiths, P Thuy-Boun, V Cantu, K Weldon, C Challis, ... BioRxiv, 2021 | 7 | 2021 |
| Transduction of systemically administered adeno-associated virus in the colonic enteric nervous system and c-kit cells of adult mice L Wang, PQ Yuan, C Challis, S Ravindra Kumar, Y Taché Frontiers in Neuroanatomy 16, 884280, 2022 | 4 | 2022 |
| Multicolor sparse viral labeling and 3D digital tracing of enteric plexus in mouse proximal colon using a novel adeno‐associated virus capsid L Wang, C Challis, S Li, CC Fowlkes, S Ravindra Kumar, PQ Yuan, ... Neurogastroenterology & Motility 33 (8), e14014, 2021 | 3 | 2021 |
| Targeted activation of enteric neurons shapes the gut environment of mice BB Yoo, JA Griffiths, PS Thuy-Boun, V Cantu, KC Weldon, C Challis, ... | 1 | 2021 |
| Optogenetic modulation of the prefrontocortical-dorsal raphe microcircuit bidirectionally biases socioaffective decisions after social defeat C Challis, C Min, SG Beck, O Berton Neuropsychopharmacology 39, S139-S139, 2014 | 1 | 2014 |
| Author's Accepted Manuscript J Jochems, SL Teegarden, Y Chen, J Boulden, C Challis, GA Ben-Dor, ... | | 2014 |
Viviana GradinaruProfessor of Neuroscience and Biological Engineering at CaltechEmail verificata su caltech.edu