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Philip Jones
Philip Jones
Wellcome Trust Sanger Institute & Oncology Department, University of Cambridge
Email verificata su sanger.ac.uk
Titolo
Citata da
Citata da
Anno
High burden and pervasive positive selection of somatic mutations in normal human skin
I Martincorena, A Roshan, M Gerstung, P Ellis, P Van Loo, S McLaren, ...
Science 348 (6237), 880-886, 2015
18812015
Separation of human epidermal stem cells from transit amplifying cells on the basis of differences in integrin function and expression
PH Jones, FM Watt
Cell 73 (4), 713-724, 1993
14911993
Clock-like mutational processes in human somatic cells
LB Alexandrov, PH Jones, DC Wedge, JE Sale, PJ Campbell, ...
Nature genetics 47 (12), 1402-1407, 2015
10752015
Somatic mutant clones colonize the human esophagus with age
I Martincorena, JC Fowler, A Wabik, ARJ Lawson, F Abascal, MWJ Hall, ...
Science 362 (6417), 911-917, 2018
10652018
Stem cell patterning and fate in human epidermis
PH Jones, S Harper, FM Watt
Cell 80 (1), 83-93, 1995
10601995
A single type of progenitor cell maintains normal epidermis
E Clayton, DP Doupé, AM Klein, DJ Winton, BD Simons, PH Jones
Nature 446 (7132), 185-189, 2007
10422007
Stimulation of human epidermal differentiation by Delta–Notch signalling at the boundaries of stem-cell clusters
S Lowell, P Jones, I Le Roux, J Dunne, FM Watt
Current Biology 10 (9), 491-500, 2000
5862000
Developmental cell programs are co-opted in inflammatory skin disease
G Reynolds, P Vegh, J Fletcher, EFM Poyner, E Stephenson, I Goh, ...
Science 371 (6527), eaba6500, 2021
3752021
A single progenitor population switches behavior to maintain and repair esophageal epithelium
DP Doupé, MP Alcolea, A Roshan, G Zhang, AM Klein, BD Simons, ...
Science 337 (6098), 1091-1093, 2012
3482012
The ordered architecture of murine ear epidermis is maintained by progenitor cells with random fate
DP Doupé, AM Klein, BD Simons, PH Jones
Developmental cell 18 (2), 317-323, 2010
2792010
Stromal expression of Jagged 1 promotes colony formation by fetal hematopoietic progenitor cells
P Jones, G May, L Healy, J Brown, G Hoyne, S Delassus, T Enver
Blood, The Journal of the American Society of Hematology 92 (5), 1505-1511, 1998
2041998
Sic transit gloria: farewell to the epidermal transit amplifying cell?
PH Jones, BD Simons, FM Watt
Cell stem cell 1 (4), 371-381, 2007
2002007
Differentiation imbalance in single oesophageal progenitor cells causes clonal immortalization and field change
MP Alcolea, P Greulich, A Wabik, J Frede, BD Simons, PH Jones
Nature cell biology 16 (6), 612-619, 2014
1922014
Hypoxia-selective targeting by the bioreductive prodrug AQ4N in patients with solid tumors: results of a phase I study
MR Albertella, PM Loadman, PH Jones, RM Phillips, R Rampling, ...
Clinical cancer research 14 (4), 1096-1104, 2008
1622008
Notch signaling regulates the differentiation of post-mitotic intestinal epithelial cells
V Zecchini, R Domaschenz, D Winton, P Jones
Genes & development 19 (14), 1686-1691, 2005
1502005
Spatial competition shapes the dynamic mutational landscape of normal esophageal epithelium
B Colom, MP Alcolea, G Piedrafita, MWJ Hall, A Wabik, SC Dentro, ...
Nature genetics 52 (6), 604-614, 2020
1482020
Expression and function of the keratinocyte integrins
FM Watt, PH Jones
Development 119 (Supplement), 185-192, 1993
1481993
Mutant clones in normal epithelium outcompete and eliminate emerging tumours
B Colom, A Herms, MWJ Hall, SC Dentro, C King, RK Sood, MP Alcolea, ...
Nature 598, 510–514, 2021
1432021
Stochastic fate of p53-mutant epidermal progenitor cells is tilted toward proliferation by UV B during preneoplasia
AM Klein, DE Brash, PH Jones, BD Simons
Proceedings of the National Academy of Sciences 107 (1), 270-275, 2010
1312010
Role for amplification and expression of glypican-5 in rhabdomyosarcoma
D Williamson, J Selfe, T Gordon, YJ Lu, K Pritchard-Jones, K Murai, ...
Cancer research 67 (1), 57-65, 2007
1232007
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