Advances in targeting the folate receptor in the treatment/imaging of cancers M Fernández, F Javaid, V Chudasama Chemical science 9 (4), 790-810, 2018 | 524 | 2018 |
Recent advances in the construction of antibody–drug conjugates V Chudasama, A Maruani, S Caddick Nature chemistry 8 (2), 114-119, 2016 | 389 | 2016 |
Platinum nanocatalyst amplification: redefining the gold standard for lateral flow immunoassays with ultrabroad dynamic range CN Loynachan, MR Thomas, ER Gray, DA Richards, J Kim, BS Miller, ... ACS nano 12 (1), 279-288, 2018 | 380 | 2018 |
Antibody fragments as nanoparticle targeting ligands: a step in the right direction DA Richards, A Maruani, V Chudasama Chemical science 8 (1), 63-77, 2017 | 352 | 2017 |
A plug-and-play approach to antibody-based therapeutics via a chemoselective dual click strategy A Maruani, MEB Smith, E Miranda, KA Chester, V Chudasama, S Caddick Nature communications 6 (1), 6645, 2015 | 279 | 2015 |
Motional timescale predictions by molecular dynamics simulations: case study using proline and hydroxyproline sidechain dynamics AE Aliev, M Kulke, HS Khaneja, V Chudasama, TD Sheppard, ... Proteins: Structure, Function, and Bioinformatics 82 (2), 195-215, 2014 | 251 | 2014 |
Antibody–PROTAC conjugates enable HER2-dependent targeted protein degradation of BRD4 M Maneiro, N Forte, MM Shchepinova, CS Kounde, V Chudasama, ... ACS chemical biology 15 (6), 1306-1312, 2020 | 247 | 2020 |
Hydroacylation of α, β-unsaturated esters via aerobic C–H activation V Chudasama, RJ Fitzmaurice, S Caddick Nature chemistry 2 (7), 592-596, 2010 | 203 | 2010 |
Next generation maleimides enable the controlled assembly of antibody–drug conjugates via native disulfide bond bridging FF Schumacher, JPM Nunes, A Maruani, V Chudasama, MEB Smith, ... Organic & biomolecular chemistry 12 (37), 7261-7269, 2014 | 188 | 2014 |
Functional native disulfide bridging enables delivery of a potent, stable and targeted antibody–drug conjugate (ADC) JPM Nunes, M Morais, V Vassileva, E Robinson, VS Rajkumar, ... Chemical Communications 51 (53), 10624-10627, 2015 | 143 | 2015 |
Minireview: Addressing the retro-Michael instability of maleimide bioconjugates PA Szijj, C Bahou, V Chudasama Drug Discovery Today: Technologies 30, 27-34, 2018 | 141 | 2018 |
Bromopyridazinedione-mediated protein and peptide bioconjugation V Chudasama, MEB Smith, FF Schumacher, D Papaioannou, G Waksman, ... Chemical Communications 47 (31), 8781-8783, 2011 | 128 | 2011 |
Forming next-generation antibody–nanoparticle conjugates through the oriented installation of non-engineered antibody fragments MK Greene, DA Richards, JCF Nogueira, K Campbell, P Smyth, ... Chemical science 9 (1), 79-87, 2018 | 120 | 2018 |
Next-generation disulfide stapling: reduction and functional re-bridging all in one MTW Lee, A Maruani, JR Baker, S Caddick, V Chudasama Chemical Science 7 (1), 799-802, 2016 | 108 | 2016 |
Acid-cleavable thiomaleamic acid linker for homogeneous antibody–drug conjugation L Castañeda, A Maruani, FF Schumacher, E Miranda, V Chudasama, ... Chemical Communications 49 (74), 8187-8189, 2013 | 104 | 2013 |
Regioselective and stoichiometrically controlled conjugation of photodynamic sensitizers to a HER2 targeting antibody fragment F Bryden, A Maruani, H Savoie, V Chudasama, MEB Smith, S Caddick, ... Bioconjugate chemistry 25 (3), 611-617, 2014 | 99 | 2014 |
Optimisation of the dibromomaleimide (DBM) platform for native antibody conjugation by accelerated post-conjugation hydrolysis M Morais, JPM Nunes, K Karu, N Forte, I Benni, MEB Smith, S Caddick, ... Organic & Biomolecular Chemistry 15 (14), 2947-2952, 2017 | 91 | 2017 |
Pyridazinediones deliver potent, stable, targeted and efficacious antibody–drug conjugates (ADCs) with a controlled loading of 4 drugs per antibody E Robinson, JPM Nunes, V Vassileva, A Maruani, JCF Nogueira, ... RSC advances 7 (15), 9073-9077, 2017 | 86 | 2017 |
Cysteine protecting groups: applications in peptide and protein science RJ Spears, C McMahon, V Chudasama Chemical Society Reviews 50 (19), 11098-11155, 2021 | 85 | 2021 |
Highly homogeneous antibody modification through optimisation of the synthesis and conjugation of functionalised dibromopyridazinediones C Bahou, DA Richards, A Maruani, EA Love, F Javaid, S Caddick, ... Organic & biomolecular chemistry 16 (8), 1359-1366, 2018 | 84 | 2018 |