| Dissecting temporal and spatial control of cytokinesis with a myosin II Inhibitor AF Straight, A Cheung, J Limouze, I Chen, NJ Westwood, JR Sellers, ... Science 299 (5613), 1743-1747, 2003 | 1631 | 2003 |
| The emergence of competition between model protocells IA Chen, RW Roberts, JW Szostak Science 305 (5689), 1474-1476, 2004 | 483 | 2004 |
| Spontaneous network formation among cooperative RNA replicators N Vaidya, ML Manapat, IA Chen, R Xulvi-Brunet, EJ Hayden, N Lehman Nature 491 (7422), 72-77, 2012 | 438 | 2012 |
| RNA catalysis in model protocell vesicles IA Chen, K Salehi-Ashtiani, JW Szostak Journal of the American Chemical Society 127 (38), 13213-13219, 2005 | 302 | 2005 |
| A kinetic study of the growth of fatty acid vesicles IA Chen, JW Szostak Biophysical journal 87 (2), 988-998, 2004 | 286 | 2004 |
| From self-assembled vesicles to protocells IA Chen, P Walde Cold Spring Harbor perspectives in biology 2 (7), a002170, 2010 | 266 | 2010 |
| Rapid colorimetric detection of bacterial species through the capture of gold nanoparticles by chimeric phages H Peng, IA Chen Acs Nano 13 (2), 1244-1252, 2018 | 218 | 2018 |
| Membrane growth can generate a transmembrane pH gradient in fatty acid vesicles IA Chen, JW Szostak Proceedings of the National Academy of Sciences 101 (21), 7965-7970, 2004 | 196 | 2004 |
| The RNA world as a model system to study the origin of life A Pressman, C Blanco, IA Chen Current Biology 25 (19), R953-R963, 2015 | 179 | 2015 |
| Comprehensive experimental fitness landscape and evolutionary network for small RNA JI Jiménez, R Xulvi-Brunet, GW Campbell, R Turk-MacLeod, IA Chen Proceedings of the National Academy of Sciences 110 (37), 14984-14989, 2013 | 171 | 2013 |
| Effect of stalling after mismatches on the error catastrophe in nonenzymatic nucleic acid replication S Rajamani, JK Ichida, T Antal, DA Treco, K Leu, MA Nowak, JW Szostak, ... Journal of the American Chemical Society 132 (16), 5880-5885, 2010 | 130 | 2010 |
| Microbial predictors of healing and short-term effect of debridement on the microbiome of chronic wounds S Verbanic, Y Shen, J Lee, JM Deacon, IA Chen NPJ biofilms and microbiomes 6 (1), 21, 2020 | 127 | 2020 |
| Controlled phage therapy by photothermal ablation of specific bacterial species using gold nanorods targeted by chimeric phages H Peng, RE Borg, LP Dow, BL Pruitt, IA Chen Proceedings of the National Academy of Sciences 117 (4), 1951-1961, 2020 | 123 | 2020 |
| Inhibition of bacterial conjugation by phage M13 and its protein g3p: quantitative analysis and model A Lin, J Jimenez, J Derr, P Vera, ML Manapat, KM Esvelt, L Villanueva, ... PloS one 6 (5), e19991, 2011 | 105 | 2011 |
| The prebiotic evolutionary advantage of transferring genetic information from RNA to DNA K Leu, B Obermayer, S Rajamani, U Gerland, IA Chen Nucleic acids research 39 (18), 8135-8147, 2011 | 97 | 2011 |
| Mapping a systematic ribozyme fitness landscape reveals a frustrated evolutionary network for self-aminoacylating RNA AD Pressman, Z Liu, E Janzen, C Blanco, UF Müller, GF Joyce, ... Journal of the American Chemical Society 141 (15), 6213-6223, 2019 | 85 | 2019 |
| A strategically positioned cation is crucial for efficient catalysis by chorismate mutase P Kast, C Grisostomi, IA Chen, S Li, U Krengel, Y Xue, D Hilvert Journal of Biological Chemistry 275 (47), 36832-36838, 2000 | 80 | 2000 |
| The emergence of cells during the origin of life IA Chen Science 314 (5805), 1558-1559, 2006 | 72 | 2006 |
| Cascade of reduced speed and accuracy after errors in enzyme-free copying of nucleic acid sequences K Leu, E Kervio, B Obermayer, RM Turk-MacLeod, C Yuan, ... Journal of the American Chemical Society 135 (1), 354-366, 2013 | 71 | 2013 |
| Lipid vesicles chaperone an encapsulated RNA aptamer R Saha, S Verbanic, IA Chen Nature communications 9 (1), 2313, 2018 | 68 | 2018 |