| Genomic regions flanking E-box binding sites influence DNA binding specificity of bHLH transcription factors through DNA shape R Gordân, N Shen, I Dror, T Zhou, J Horton, R Rohs, ML Bulyk Cell reports 3 (4), 1093-1104, 2013 | 384 | 2013 |
| Aberrant mitochondrial fission in neurons induced by protein kinase Cδ under oxidative stress conditions in vivo X Qi, MH Disatnik, N Shen, RA Sobel, D Mochly-Rosen Molecular biology of the cell 22 (2), 256-265, 2011 | 301 | 2011 |
| Quantitative modeling of transcription factor binding specificities using DNA shape T Zhou, N Shen, L Yang, N Abe, J Horton, RS Mann, HJ Bussemaker, ... Proceedings of the National Academy of Sciences 112 (15), 4654-4659, 2015 | 268 | 2015 |
| Proteome-wide mapping of short-lived proteins in human cells J Li, Z Cai, LP Vaites, N Shen, DC Mitchell, EL Huttlin, JA Paulo, BL Harry, ... Molecular cell 81 (22), 4722-4735. e5, 2021 | 104 | 2021 |
| Establishment of expression in the SHORTROOT-SCARECROW transcriptional cascade through opposing activities of both activators and repressors EE Sparks, C Drapek, A Gaudinier, S Li, M Ansariola, N Shen, ... Developmental Cell 39 (5), 585-596, 2016 | 64 | 2016 |
| Divergence in DNA specificity among paralogous transcription factors contributes to their differential in vivo binding N Shen, J Zhao, JL Schipper, Y Zhang, T Bepler, D Leehr, J Bradley, ... Cell systems 6 (4), 470-483. e8, 2018 | 58 | 2018 |
| p38α regulates expression of DUX4 in a model of facioscapulohumeral muscular dystrophy LA Rojas, E Valentine, A Accorsi, J Maglio, N Shen, A Robertson, ... The Journal of Pharmacology and Experimental Therapeutics 374 (3), 489-498, 2020 | 42 | 2020 |
| Integration of cancer gene co-expression network and metabolic network to uncover potential cancer drug targets J Chen, M Ma, N Shen, JJ Xi, W Tian Journal of proteome research 12 (6), 2354-2364, 2013 | 28 | 2013 |
| Single-cell gene fusion detection by scFusion Z Jin, W Huang, N Shen, J Li, X Wang, J Dong, PJ Park, R Xi Nature Communications 13 (1), 1084, 2022 | 24 | 2022 |
| Low-input lipidomics reveals lipid metabolism remodelling during early mammalian embryo development L Zhang, J Zhao, SM Lam, L Chen, Y Gao, W Wang, Y Xu, T Tan, H Yu, ... Nature Cell Biology 26 (2), 278-293, 2024 | 23 | 2024 |
| MAGPIE: accurate pathogenic prediction for multiple variant types using machine learning approach Y Liu, T Zhang, N You, S Wu, N Shen Genome Medicine 16 (1), 3, 2024 | 9 | 2024 |
| Temporally integrated transcriptome analysis reveals ASFV pathology and host response dynamics L Lv, T Zhang, H Jia, Y Zhang, A Ahsan, X Zhao, T Chen, Z Shen, N Shen Frontiers in Immunology 13, 995998, 2022 | 7 | 2022 |
| P38 kinase inhibitors reduce DUX4 and downstream gene expression for the treatment of FSHD AM Cacace, LGAR SOTO, LA Thompson III, OB Wallace, LV Ronco, ... US Patent 10,537,560, 2020 | 5 | 2020 |
| P38 kinase inhibitors reduce DUX4 and downstream gene expression for the treatment of FSHD AM Cacace, LGAR SOTO, LA Thompson III, OB Wallace, LV Ronco, ... US Patent 10,342,786, 2019 | 5 | 2019 |
| Mitophagy defect mediates the aging‐associated hallmarks in Hutchinson–Gilford progeria syndrome Y Sun, L Xu, Y Li, S Jia, G Wang, X Cen, Y Xu, Z Cao, J Wang, N Shen, ... Aging cell 23 (6), e14143, 2024 | 4 | 2024 |
| De novo identification of expressed cancer somatic mutations from single-cell RNA sequencing data T Zhang, H Jia, T Song, L Lv, DC Gulhan, H Wang, W Guo, R Xi, H Guo, ... Genome Medicine 15 (1), 115, 2023 | 4 | 2023 |
| Identifying autism spectrum disorder from multi-modal data with privacy-preserving H Wang, H Jing, J Yang, C Liu, L Hu, G Tao, Z Zhao, N Shen npj Mental Health Research 3 (1), 15, 2024 | 3 | 2024 |
| Beyond radiologist-level liver lesion detection on multi-phase contrast-enhanced CT images by deep learning L Wu, H Wang, Y Chen, X Zhang, T Zhang, N Shen, G Tao, Z Sun, Y Ding, ... Iscience 26 (11), 2023 | 3 | 2023 |
| Intrinsic specificity differences between transcription factor paralogs partly explain their differential in vivo binding N Shen, J Zhao, J Schipper, Y Zhang, T Bepler, D Leehr, J Bradley, ... bioRxiv, 208561, 2017 | 2 | 2017 |
| SpliceTransformer predicts tissue-specific splicing linked to human diseases N You, C Liu, Y Gu, R Wang, H Jia, T Zhang, S Jiang, J Shi, M Chen, ... Nature Communications 15 (1), 9129, 2024 | 1 | 2024 |
Raluca GordanAssociate Professor, Duke UniversityEmail verificata su duke.edu