| Cutting edge: NF-κB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression FG Bauernfeind, G Horvath, A Stutz, ES Alnemri, K MacDonald, D Speert, ... The Journal of Immunology 183 (2), 787-791, 2009 | 3197 | 2009 |
| AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA T Fernandes-Alnemri, JW Yu, P Datta, J Wu, ES Alnemri Nature 458 (7237), 509-513, 2009 | 2134 | 2009 |
| CPP32, a novel human apoptotic protein with homology to Caenorhabditis elegans cell death protein Ced-3 and mammalian interleukin-1 beta-converting enzyme. T Fernandes-Alnemri, G Litwack, ES Alnemri Journal of Biological Chemistry 269 (49), 30761-30764, 1994 | 1698 | 1994 |
| Autoactivation of procaspase-9 by Apaf-1-mediated oligomerization SM Srinivasula, M Ahmad, T Fernandes-Alnemri, ES Alnemri Molecular cell 1 (7), 949-957, 1998 | 1551 | 1998 |
| A conserved XIAP-interaction motif in caspase-9 and Smac/DIABLO regulates caspase activity and apoptosis SM Srinivasula, R Hegde, A Saleh, P Datta, E Shiozaki, J Chai, RA Lee, ... Nature 410 (6824), 112-116, 2001 | 1413 | 2001 |
| Cleavage of DFNA5 by caspase-3 during apoptosis mediates progression to secondary necrotic/pyroptotic cell death C Rogers, T Fernandes-Alnemri, L Mayes, D Alnemri, G Cingolani, ... Nature communications 8 (1), 14128, 2017 | 1298 | 2017 |
| The pyroptosome: a supramolecular assembly of ASC dimers mediating inflammatory cell death via caspase-1 activation T Fernandes-Alnemri, J Wu, JW Yu, P Datta, B Miller, W Jankowski, ... Cell Death & Differentiation 14 (9), 1590-1604, 2007 | 1219 | 2007 |
| Identification of Omi/HtrA2 as a mitochondrial apoptotic serine protease that disrupts inhibitor of apoptosis protein-caspase interaction R Hegde, SM Srinivasula, ZJ Zhang, R Wassell, R Mukattash, L Cilenti, ... Journal of Biological Chemistry 277 (1), 432-438, 2002 | 1031 | 2002 |
| In vitro activation of CPP32 and Mch3 by Mch4, a novel human apoptotic cysteine protease containing two FADD-like domains. T Fernandes-Alnemri, RC Armstrong, J Krebs, SM Srinivasula, L Wang, ... Proceedings of the National Academy of Sciences 93 (15), 7464-7469, 1996 | 1027 | 1996 |
| Non-transcriptional priming and deubiquitination regulate NLRP3 inflammasome activation C Juliana, T Fernandes-Alnemri, S Kang, A Farias, F Qin, ES Alnemri Journal of Biological Chemistry 287 (43), 36617-36622, 2012 | 883 | 2012 |
| The AIM2 inflammasome is critical for innate immunity to Francisella tularensis T Fernandes-Alnemri, JW Yu, C Juliana, L Solorzano, S Kang, J Wu, ... Nature immunology 11 (5), 385-393, 2010 | 866 | 2010 |
| Identification and molecular cloning of two novel receptors for the cytotoxic ligand TRAIL M MacFarlane, M Ahmad, SM Srinivasula, T Fernandes-Alnemri, ... Journal of Biological Chemistry 272 (41), 25417-25420, 1997 | 789 | 1997 |
| Molecular ordering of the Fas-apoptotic pathway: the Fas/APO-1 protease Mch5 is a CrmA-inhibitable protease that activates multiple Ced-3/ICE-like cysteine proteases SM Srinivasula, M Ahmad, T Fernandes-Alnemri, G Litwack, ES Alnemri Proceedings of the National Academy of Sciences 93 (25), 14486-14491, 1996 | 761 | 1996 |
| Cleavage of lamin A by Mch2 alpha but not CPP32: multiple interleukin 1 beta-converting enzyme-related proteases with distinct substrate recognition properties are active in … A Takahashi, ES Alnemri, YA Lazebnik, T Fernandes-Alnemri, G Litwack, ... Proceedings of the National Academy of Sciences 93 (16), 8395-8400, 1996 | 711 | 1996 |
| Gasdermin pores permeabilize mitochondria to augment caspase-3 activation during apoptosis and inflammasome activation C Rogers, DA Erkes, A Nardone, AE Aplin, T Fernandes-Alnemri, ... Nature communications 10 (1), 1689, 2019 | 699 | 2019 |
| Caspase-2 induces apoptosis by releasing proapoptotic proteins from mitochondria Y Guo, SM Srinivasula, A Druilhe, T Fernandes-Alnemri, ES Alnemri Journal of Biological Chemistry 277 (16), 13430-13437, 2002 | 671 | 2002 |
| Anti-inflammatory compounds parthenolide and Bay 11-7082 are direct inhibitors of the inflammasome C Juliana, T Fernandes-Alnemri, J Wu, P Datta, L Solorzano, JW Yu, ... Journal of Biological Chemistry 285 (13), 9792-9802, 2010 | 652 | 2010 |
| Mch2, a New Member of the Apoptotic Ced-3/Ice Cysteine Protease Gene Family T Fernandes-Alnemri, G Litwack, ES Alnemri Cancer research 55 (13), 2737-2742, 1995 | 597 | 1995 |
| Identification of Ipaf, a human caspase-1-activating protein related to Apaf-1 JL Poyet, SM Srinivasula, M Tnani, M Razmara, T Fernandes-Alnemri, ... Journal of Biological Chemistry 276 (30), 28309-28313, 2001 | 552 | 2001 |
| Mch3, a novel human apoptotic cysteine protease highly related to CPP32 T Fernandes-Alnemri, A Takahashi, R Armstrong, J Krebs, L Fritz, ... Cancer research 55 (24), 6045-6052, 1995 | 532 | 1995 |
Emad AlnemriThomas Eakins Professor of Biochemistry and Molecular Biology, Thomas Jefferson UniversityEmail verificata su jefferson.edu
