Lysosome-targeting chimaeras for degradation of extracellular proteins SM Banik, K Pedram, S Wisnovsky, G Ahn, NM Riley, CR Bertozzi Nature 584 (7820), 291-297, 2020 | 791 | 2020 |
Spatially resolved proteomic mapping in living cells with the engineered peroxidase APEX2 V Hung, ND Udeshi, SS Lam, KH Loh, KJ Cox, K Pedram, SA Carr, ... Nature Protocols 11 (3), 456-75, 2016 | 587 | 2016 |
Small RNAs are modified with N-glycans and displayed on the surface of living cells RA Flynn, K Pedram, SA Malaker, PJ Batista, BAH Smith, AG Johnson, ... Cell 184 (12), 3109-3124. e22, 2021 | 447 | 2021 |
Physical Principles of Membrane Shape Regulation by the Glycocalyx CR Shurer*, JCH Kuo*, LDM Roberts*, JG Gandhi, MJ Colville, TA Enoki, ... Cell 177 (7), 1757-1770, 2019 | 256 | 2019 |
The mucin-selective protease StcE enables molecular and functional analysis of human cancer-associated mucins SA Malaker*, K Pedram*, MJ Ferracane, BA Bensing, V Krishnan, C Pett, ... Proceedings of the National Academy of Sciences 116 (15), 7278–7287, 2019 | 242 | 2019 |
Antibodies to biotin enable large-scale detection of biotinylation sites on proteins ND Udeshi, K Pedram, T Svinkina, S Fereshetian, SA Myers, O Aygun, ... Nature Methods 14 (12), 1167–1170, 2017 | 146 | 2017 |
Genome-wide CRISPR screens reveal a specific ligand for the glycan-binding immune checkpoint receptor Siglec-7 S Wisnovsky, L Möckl, SA Malaker, K Pedram, GT Hess, NM Riley, ... Proceedings of the National Academy of Sciences 118 (5), e2015024118, 2021 | 111 | 2021 |
An enzymatic toolkit for selective proteolysis, detection, and visualization of mucin-domain glycoproteins DJ Shon, SA Malaker, K Pedram, E Yang, V Krishnan, O Dorigo, ... Proceedings of the National Academy of Sciences 117 (35), 21299-21307, 2020 | 106 | 2020 |
Quantitative super-resolution microscopy of the mammalian glycocalyx L Möckl*, K Pedram*, AR Roy, V Krishnan, AK Gustavsson, O Dorigo, ... Developmental Cell 50 (1), 57-72, 2019 | 103 | 2019 |
Bump-and-hole engineering identifies specific substrates of glycosyltransferases in living cells B Schumann, SA Malaker, SP Wisnovsky, MF Debets, AJ Agbay, ... Molecular cell 78 (5), 824-834. e15, 2020 | 97 | 2020 |
A bulky glycocalyx fosters metastasis formation by promoting G1 cell cycle progression EC Woods, FB Kai, JM Barnes, K Pedram, MW Pickup, MJ Hollander, ... eLife 6, e25752, 2017 | 85 | 2017 |
Revealing the human mucinome SA Malaker*, NM Riley*, DJ Shon, K Pedram, V Krishnan, O Dorigo, ... Nature communications 13 (1), 1-13, 2022 | 72 | 2022 |
Design of a mucin-selective protease for targeted degradation of cancer-associated mucins K Pedram*, DJ Shon*, GS Tender*, NR Mantuano, JJ Northey, KJ Metcalf, ... Nature Biotechnology 42 (4), 597-607, 2023 | 47 | 2023 |
An acquired and endogenous glycocalyx forms a bidirectional “don’t eat” and “don’t eat me” barrier to phagocytosis PRC Imbert, A Saric, K Pedram, CR Bertozzi, S Grinstein, SA Freeman Current Biology 31 (1), 77-89. e5, 2021 | 46 | 2021 |
Pediatric epilepsy surgery: long-term 5-year seizure remission and medication use JS Hauptman, K Pedram, CA Sison, R Sankar, N Salamon, HV Vinters, ... Neurosurgery 71 (5), 985-993, 2012 | 34 | 2012 |
Membrane curvature regulates the spatial distribution of bulky glycoproteins CH Lu, K Pedram, CT Tsai, T Jones IV, X Li, ML Nakamoto, CR Bertozzi, ... Nature Communications 13 (1), 3093, 2022 | 31 | 2022 |
Small molecule inhibitors of mammalian glycosylation K Almahayni, M Spiekermann, A Fiore, G Yu, K Pedram†, L Möckl† Matrix Biology Plus, 100108, 2022 | 22 | 2022 |
Lysosomal cathepsin D mediates endogenous mucin glycodomain catabolism in mammals K Pedram, NN Laqtom, DJ Shon, A Di Spiezio, NM Riley, P Saftig, ... Proceedings of the National Academy of Sciences 119 (39), e2117105119, 2022 | 13 | 2022 |
Enzymatically enhanced ultrastructure expansion microscopy unlocks expansion of in vitro Toxoplasma gondii cysts K Bondarenko, F Limoge, K Pedram, M Gissot, JC Young Msphere 9 (9), e00322-24, 2024 | 1 | 2024 |
Bifunctional Molecules for Lysosomal Targeting and Related Compositions and Methods C Bertozzi, S Banik, K Pedram, G Ahn US Patent App. 17/311,779, 2022 | 1 | 2022 |