| AlphaFold accelerates artificial intelligence powered drug discovery: efficient discovery of a novel CDK20 small molecule inhibitor F Ren, X Ding, M Zheng, M Korzinkin, X Cai, W Zhu, A Mantsyzov, ... Chemical science 14 (6), 1443-1452, 2023 | 182 | 2023 |
| Chemistry42: an AI-driven platform for molecular design and optimization YA Ivanenkov, D Polykovskiy, D Bezrukov, B Zagribelnyy, V Aladinskiy, ... Journal of Chemical Information and Modeling 63 (3), 695-701, 2023 | 104 | 2023 |
| Discovery of biaryl amides as potent, orally bioavailable, and CNS penetrant RORγt inhibitors Y Wang, W Cai, Y Cheng, T Yang, Q Liu, G Zhang, Q Meng, F Han, ... ACS Medicinal Chemistry Letters 6 (7), 787-792, 2015 | 77 | 2015 |
| A small-molecule TNIK inhibitor targets fibrosis in preclinical and clinical models F Ren, A Aliper, J Chen, H Zhao, S Rao, C Kuppe, IV Ozerov, M Zhang, ... Nature Biotechnology, 1-13, 2024 | 72 | 2024 |
| Identification of therapeutic targets for amyotrophic lateral sclerosis using PandaOmics–an AI-enabled biological target discovery platform FW Pun, BHM Liu, X Long, HW Leung, GHD Leung, QT Mewborne, J Gao, ... Frontiers in aging neuroscience 14, 914017, 2022 | 69 | 2022 |
| Hallmarks of aging-based dual-purpose disease and age-associated targets predicted using PandaOmics AI-powered discovery engine FW Pun, GHD Leung, HW Leung, BHM Liu, X Long, IV Ozerov, J Wang, ... Aging (Albany NY) 14 (6), 2475, 2022 | 64 | 2022 |
| Mild and Regioselective N-Alkylation of 2-Pyridones in Water X Hao, Z Xu, H Lu, X Dai, T Yang, X Lin, F Ren Organic Letters 17 (14), 3382-3385, 2015 | 59 | 2015 |
| Quantum computing for near-term applications in generative chemistry and drug discovery A Pyrkov, A Aliper, D Bezrukov, YC Lin, D Polykovskiy, P Kamya, F Ren, ... Drug Discovery Today 28 (8), 103675, 2023 | 51 | 2023 |
| Efficient and C2-selective arylation of indoles, benzofurans, and benzothiophenes with iodobenzenes in water at room temperature Z Xu, Y Xu, H Lu, T Yang, X Lin, L Shao, F Ren Tetrahedron 71 (18), 2616-2621, 2015 | 49 | 2015 |
| Prediction of Clinical Trials Outcomes Based on Target Choice and Clinical Trial Design with Multi‐Modal Artificial Intelligence A Aliper, R Kudrin, D Polykovskiy, P Kamya, E Tutubalina, S Chen, F Ren, ... Clinical Pharmacology & Therapeutics 114 (5), 972-980, 2023 | 48 | 2023 |
| Exploring the advantages of quantum generative adversarial networks in generative chemistry PY Kao, YC Yang, WY Chiang, JY Hsiao, Y Cao, A Aliper, F Ren, ... Journal of Chemical Information and Modeling 63 (11), 3307-3318, 2023 | 46 | 2023 |
| Leucine-rich repeat kinase 2 inhibitors: a patent review (2014-present) X Ding, F Ren Expert opinion on therapeutic patents 30 (4), 275-286, 2020 | 37 | 2020 |
| Discovery of N-(4-aryl-5-aryloxy-thiazol-2-yl)-amides as potent RORγt inverse agonists Y Wang, T Yang, Q Liu, Y Ma, L Yang, L Zhou, Z Xiang, Z Cheng, S Lu, ... Bioorganic & Medicinal Chemistry 23 (17), 5293-5302, 2015 | 35 | 2015 |
| PandaOmics: an AI-driven platform for therapeutic target and biomarker discovery P Kamya, IV Ozerov, FW Pun, K Tretina, T Fokina, S Chen, V Naumov, ... Journal of Chemical Information and Modeling 64 (10), 3961-3969, 2024 | 33 | 2024 |
| From RORγt agonist to two types of RORγt inverse agonists Y Wang, W Cai, T Tang, Q Liu, T Yang, L Yang, Y Ma, G Zhang, Y Huang, ... ACS Medicinal Chemistry Letters 9 (2), 120-124, 2018 | 30 | 2018 |
| A mild and regioselective Ullmann reaction of indazoles with aryliodides in water X Ding, J Bai, H Wang, B Zhao, J Li, F Ren Tetrahedron 73 (2), 172-178, 2017 | 30 | 2017 |
| Discovery of Novel 1,2,4-Thiadiazole Derivatives as Potent, Orally Active Agonists of Sphingosine 1-Phosphate Receptor Subtype 1 (S1P1) F Ren, G Deng, H Wang, L Luan, Q Meng, Q Xu, H Xu, X Xu, H Zhang, ... Journal of Medicinal Chemistry 55 (9), 4286-4296, 2012 | 29 | 2012 |
| A mild and efficient carboxylate-directed C–H arylation of aryl carboxylic acids with iodobenzenes in water Z Xu, T Yang, X Lin, JD Elliott, F Ren Tetrahedron Letters 56 (2), 475-477, 2015 | 27 | 2015 |
| The hitchhiker’s guide to deep learning driven generative chemistry Y Ivanenkov, B Zagribelnyy, A Malyshev, S Evteev, V Terentiev, P Kamya, ... ACS Medicinal Chemistry Letters 14 (7), 901-915, 2023 | 25 | 2023 |
| Investigations on the intrinsic viscosity of poly (vinyl chloride)(PVC) affected by polymer–polymer interactions in solution Y Haiyang, Z Pingping, L Guofeng, W Peng, R Feng European polymer journal 35 (2), 345-353, 1999 | 25 | 1999 |
Alex Zhavoronkov (Aleksandrs Zavoro...Insilico MedicineEmail verificata su insilico.com