The human homologs of checkpoint kinases Chk1 and Cds1 (Chk2) phosphorylate p53 at multiple DNA damage-inducible sites SY Shieh, J Ahn, K Tamai, Y Taya, C Prives Genes & development 14 (3), 289-300, 2000 | 1379 | 2000 |
Mature HIV-1 capsid structure by cryo-electron microscopy and all-atom molecular dynamics G Zhao, JR Perilla, EL Yufenyuy, X Meng, B Chen, J Ning, J Ahn, ... Nature 497 (7451), 643-646, 2013 | 975 | 2013 |
A subset of tumor-derived mutant forms of p53 down-regulate p63 and p73 through a direct interaction with the p53 core domain C Gaiddon, M Lokshin, J Ahn, T Zhang, C Prives Molecular and cellular biology 21 (5), 1874-1887, 2001 | 614 | 2001 |
A role for p53 in base excision repair J Zhou, J Ahn, SH Wilson, C Prives The EMBO journal, 2001 | 456 | 2001 |
The Chk2 protein kinase J Ahn, M Urist, C Prives DNA repair 3 (8-9), 1039-1047, 2004 | 354 | 2004 |
Structural convergence between Cryo-EM and NMR reveals intersubunit interactions critical for HIV-1 capsid function IJL Byeon, X Meng, J Jung, G Zhao, R Yang, J Ahn, J Shi, J Concel, ... Cell 139 (4), 780-790, 2009 | 300 | 2009 |
HIV/simian immunodeficiency virus (SIV) accessory virulence factor Vpx loads the host cell restriction factor SAMHD1 onto the E3 ubiquitin ligase complex CRL4DCAF1 J Ahn, C Hao, J Yan, M DeLucia, J Mehrens, C Wang, AM Gronenborn, ... Journal of Biological Chemistry 287 (15), 12550-12558, 2012 | 222 | 2012 |
Cyclophilin A stabilizes the HIV-1 capsid through a novel non-canonical binding site C Liu, JR Perilla, J Ning, M Lu, G Hou, R Ramalho, BA Himes, G Zhao, ... Nature communications 7 (1), 10714, 2016 | 193 | 2016 |
Tetramerization of SAMHD1 is required for biological activity and inhibition of HIV infection J Yan, S Kaur, M DeLucia, C Hao, J Mehrens, C Wang, M Golczak, ... Journal of Biological Chemistry 288 (15), 10406-10417, 2013 | 183 | 2013 |
Mechanism of allosteric activation of SAMHD1 by dGTP X Ji, Y Wu, J Yan, J Mehrens, H Yang, M DeLucia, C Hao, ... Nature structural & molecular biology 20 (11), 1304-1309, 2013 | 177 | 2013 |
The C terminus of p53 binds the N-terminal domain of MDM2 MV Poyurovsky, C Katz, O Laptenko, R Beckerman, M Lokshin, J Ahn, ... Nature structural & molecular biology 17 (8), 982-989, 2010 | 177 | 2010 |
The C-terminus of p53: the more you learn the less you know J Ahn, C Prives Nature structural biology 8 (9), 730-732, 2001 | 169 | 2001 |
The host proteins transportin SR2/TNPO3 and cyclophilin A exert opposing effects on HIV-1 uncoating VB Shah, J Shi, DR Hout, I Oztop, L Krishnan, J Ahn, MS Shotwell, ... Journal of virology 87 (1), 422-432, 2013 | 168 | 2013 |
NMR structure of human restriction factor APOBEC3A reveals substrate binding and enzyme specificity IJL Byeon, J Ahn, M Mitra, CH Byeon, K Hercík, J Hritz, LM Charlton, ... Nature communications 4 (1), 1890, 2013 | 160 | 2013 |
Solid-state NMR studies of HIV-1 capsid protein assemblies Y Han, J Ahn, J Concel, IJL Byeon, AM Gronenborn, J Yang, T Polenova Journal of the American Chemical Society 132 (6), 1976-1987, 2010 | 135 | 2010 |
Questioning the role of checkpoint kinase 2 in the p53 DNA damage response J Ahn, M Urist, C Prives Journal of Biological Chemistry 278 (23), 20480-20489, 2003 | 129 | 2003 |
HIV-1 Vpr loads uracil DNA glycosylase-2 onto DCAF1, a substrate recognition subunit of a cullin 4A-ring E3 ubiquitin ligase for proteasome-dependent degradation J Ahn, T Vu, Z Novince, J Guerrero-Santoro, V Rapic-Otrin, ... Journal of Biological Chemistry 285 (48), 37333-37341, 2010 | 124 | 2010 |
CyclinA2-cyclin-dependent kinase regulates SAMHD1 protein phosphohydrolase domain J Yan, C Hao, M DeLucia, S Swanson, L Florens, MP Washburn, J Ahn, ... Journal of Biological Chemistry 290 (21), 13279-13292, 2015 | 116 | 2015 |
The DDB1–DCAF1–Vpr–UNG2 crystal structure reveals how HIV-1 Vpr steers human UNG2 toward destruction Y Wu, X Zhou, CO Barnes, M DeLucia, AE Cohen, AM Gronenborn, J Ahn, ... Nature structural & molecular biology 23 (10), 933-940, 2016 | 115 | 2016 |
Evolutionary toggling of Vpx/Vpr specificity results in divergent recognition of the restriction factor SAMHD1 OI Fregoso, J Ahn, C Wang, J Mehrens, J Skowronski, M Emerman PLoS pathogens 9 (7), e1003496, 2013 | 114 | 2013 |