A cellular census of human lungs identifies novel cell states in health and in asthma FA Vieira Braga, G Kar, M Berg, OA Carpaij, K Polanski, LM Simon, ... Nature medicine 25 (7), 1153-1163, 2019 | 842 | 2019 |
New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries N Shrine, AL Guyatt, AM Erzurumluoglu, VE Jackson, BD Hobbs, ... Nature genetics 51 (3), 481-493, 2019 | 448 | 2019 |
Cigarette smoke–induced emphysema: a role for the B cell? BWA van der Strate, DS Postma, CA Brandsma, BN Melgert, MA Luinge, ... American journal of respiratory and critical care medicine 173 (7), 751-758, 2006 | 440 | 2006 |
Lung eQTLs to help reveal the molecular underpinnings of asthma K Hao, Y Bossé, DC Nickle, PD Paré, DS Postma, M Laviolette, ... PLoS genetics 8 (11), e1003029, 2012 | 384 | 2012 |
Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets LV Wain, N Shrine, MS Artigas, AM Erzurumluoglu, B Noyvert, ... Nature genetics 49 (3), 416-425, 2017 | 314 | 2017 |
Lung ageing and COPD: is there a role for ageing in abnormal tissue repair? CA Brandsma, M de Vries, R Costa, RR Woldhuis, M Königshoff, ... European Respiratory Review 26 (146), 2017 | 227 | 2017 |
Recent advances in chronic obstructive pulmonary disease pathogenesis: from disease mechanisms to precision medicine CA Brandsma, M Van den Berge, TL Hackett, G Brusselle, W Timens The Journal of pathology 250 (5), 624-635, 2020 | 208 | 2020 |
Identification of TMPRSS2 as a Susceptibility Gene for Severe 2009 Pandemic A(H1N1) Influenza and A(H7N9) Influenza Z Cheng, J Zhou, KKW To, H Chu, C Li, D Wang, D Yang, S Zheng, K Hao, ... The Journal of infectious diseases 212 (8), 1214-1221, 2015 | 190 | 2015 |
Lymphoid follicles in (very) severe COPD: beneficial or harmful? GG Brusselle, T Demoor, KR Bracke, CA Brandsma, W Timens European Respiratory Journal 34 (1), 219-230, 2009 | 182 | 2009 |
A gene expression signature of emphysema-related lung destruction and its reversal by the tripeptide GHK JD Campbell, JE McDonough, JE Zeskind, TL Hackett, DV Pechkovsky, ... Genome medicine 4, 1-16, 2012 | 165 | 2012 |
Molecular signature of smoking in human lung tissues Y Bossé, DS Postma, DD Sin, M Lamontagne, C Couture, N Gaudreault, ... Cancer research 72 (15), 3753-3763, 2012 | 165 | 2012 |
A large lung gene expression study identifying fibulin-5 as a novel player in tissue repair in COPD CA Brandsma, M van den Berge, DS Postma, MR Jonker, S Brouwer, ... Thorax 70 (1), 21-32, 2015 | 124 | 2015 |
Sixteen new lung function signals identified through 1000 Genomes Project reference panel imputation M Soler Artigas, LV Wain, S Miller, AK Kheirallah, JE Huffman, I Ntalla, ... Nature communications 6, 2015 | 118 | 2015 |
Current perspectives on the role of interleukin-1 signalling in the pathogenesis of asthma and COPD ET Osei, CA Brandsma, W Timens, IH Heijink, TL Hackett European Respiratory Journal 55 (2), 2020 | 117 | 2020 |
Defective fibrillar collagen organization by fibroblasts contributes to airway remodeling in asthma LB Mostaço-Guidolin, ET Osei, J Ullah, S Hajimohammadi, M Fouadi, X Li, ... American journal of respiratory and critical care medicine 200 (4), 431-443, 2019 | 99 | 2019 |
Increased levels of (class switched) memory B cells in peripheral blood of current smokers CA Brandsma, MN Hylkema, M Geerlings, WH van Geffen, DS Postma, ... Respiratory research 10, 1-11, 2009 | 96 | 2009 |
miR-638 regulates gene expression networks associated with emphysematous lung destruction SA Christenson, CA Brandsma, JD Campbell, DA Knight, DV Pechkovsky, ... Genome medicine 5, 1-13, 2013 | 93 | 2013 |
Unravelling the complexity of COPD by microRNAs: it's a small world after all ET Osei, L Florez-Sampedro, W Timens, DS Postma, IH Heijink, ... European Respiratory Journal 46 (3), 807-818, 2015 | 89 | 2015 |
Sixteen new lung function signals identified through 1000 Genomes Project reference panel imputation MS Artigas, LV Wain, S Miller, AK Kheirallah, JE Huffman, I Ntalla, ... Nature communications 6 (1), 8658, 2015 | 84 | 2015 |
Characterizing smoking-induced transcriptional heterogeneity in the human bronchial epithelium at single-cell resolution GE Duclos, VH Teixeira, P Autissier, YB Gesthalter, MA Reinders-Luinge, ... Science advances 5 (12), eaaw3413, 2019 | 83 | 2019 |