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Inhibition of α-KG-dependent histone and DNA demethylases by fumarate and succinate that are accumulated in mutations of FH and SDH tumor suppressors M Xiao, H Yang, W Xu, S Ma, H Lin, H Zhu, L Liu, Y Liu, C Yang, Y Xu, ... Genes & development 26 (12), 1326-1338, 2012 | 1194 | 2012 |
Structure of the protein phosphatase 2A holoenzyme Y Xu, Y Xing, Y Chen, Y Chao, Z Lin, E Fan, WY Jong, S Strack, ... Cell 127 (6), 1239-1251, 2006 | 602 | 2006 |
Crystal structure of TET2-DNA complex: insight into TET-mediated 5mC oxidation L Hu, Z Li, J Cheng, Q Rao, W Gong, M Liu, YG Shi, J Zhu, P Wang, Y Xu Cell 155 (7), 1545-1555, 2013 | 493 | 2013 |
Structure of protein phosphatase 2A core enzyme bound to tumor-inducing toxins Y Xing, Y Xu, Y Chen, PD Jeffrey, Y Chao, Z Lin, Z Li, S Strack, JB Stock, ... Cell 127 (2), 341-353, 2006 | 445 | 2006 |
Structural insights into the YAP and TEAD complex Z Li, B Zhao, P Wang, F Chen, Z Dong, H Yang, KL Guan, Y Xu Genes & development 24 (3), 235-240, 2010 | 430 | 2010 |
Structural insight into autoinhibition and histone H3-induced activation of DNMT3A X Guo, L Wang, J Li, Z Ding, J Xiao, X Yin, S He, P Shi, L Dong, G Li, ... Nature 517 (7536), 640-644, 2015 | 420 | 2015 |
Lysine-5 acetylation negatively regulates lactate dehydrogenase A and is decreased in pancreatic cancer D Zhao, SW Zou, Y Liu, X Zhou, Y Mo, P Wang, YH Xu, B Dong, Y Xiong, ... Cancer cell 23 (4), 464-476, 2013 | 349 | 2013 |
Crystal structure of the YTH domain of YTHDF2 reveals mechanism for recognition of N6-methyladenosine T Zhu, IA Roundtree, P Wang, X Wang, L Wang, C Sun, Y Tian, J Li, C He, ... Cell research 24 (12), 1493-1496, 2014 | 345 | 2014 |
Structure of a protein phosphatase 2A holoenzyme: insights into B55-mediated Tau dephosphorylation Y Xu, Y Chen, P Zhang, PD Jeffrey, Y Shi Molecular cell 31 (6), 873-885, 2008 | 344 | 2008 |
Structural insight into substrate preference for TET-mediated oxidation L Hu, J Lu, J Cheng, Q Rao, Z Li, H Hou, Z Lou, L Zhang, W Li, W Gong, ... Nature 527 (7576), 118-122, 2015 | 309 | 2015 |
Structure of nucleosome-bound human BAF complex S He, Z Wu, Y Tian, Z Yu, J Yu, X Wang, J Li, B Liu, Y Xu Science 367 (6480), 875-881, 2020 | 293 | 2020 |
Crystal structure of severe acute respiratory syndrome coronavirus spike protein fusion core Y Xu, Z Lou, Y Liu, H Pang, P Tien, GF Gao, Z Rao Journal of Biological Chemistry 279 (47), 49414-49419, 2004 | 284 | 2004 |
PHD finger recognition of unmodified histone H3R2 links UHRF1 to regulation of euchromatic gene expression E Rajakumara, Z Wang, H Ma, L Hu, H Chen, Y Lin, R Guo, F Wu, H Li, ... Molecular cell 43 (2), 275-284, 2011 | 216 | 2011 |
Structural basis for coronavirus-mediated membrane fusion: crystal structure of mouse hepatitis virus spike protein fusion core Y Xu, Y Liu, Z Lou, L Qin, X Li, Z Bai, H Pang, P Tien, GF Gao, Z Rao Journal of Biological Chemistry 279 (29), 30514-30522, 2004 | 162 | 2004 |
Identification of Integrator-PP2A complex (INTAC), an RNA polymerase II phosphatase H Zheng, Y Qi, S Hu, X Cao, C Xu, Z Yin, X Chen, Y Li, W Liu, J Li, J Wang, ... Science 370 (6520), eabb5872, 2020 | 153 | 2020 |
Molecular mechanism for USP7-mediated DNMT1 stabilization by acetylation J Cheng, H Yang, J Fang, L Ma, R Gong, P Wang, Z Li, Y Xu Nature communications 6 (1), 7023, 2015 | 151 | 2015 |
Structural insights into preinitiation complex assembly on core promoters X Chen, Y Qi, Z Wu, X Wang, J Li, D Zhao, H Hou, Y Li, Z Yu, W Liu, ... Science 372 (6541), eaba8490, 2021 | 150 | 2021 |
Sensing and transmitting intracellular amino acid signals through reversible lysine aminoacylations XD He, W Gong, JN Zhang, J Nie, CF Yao, FS Guo, Y Lin, XH Wu, F Li, ... Cell metabolism 27 (1), 151-166. e6, 2018 | 138 | 2018 |
Structures of the human Mediator and Mediator-bound preinitiation complex X Chen, X Yin, J Li, Z Wu, Y Qi, X Wang, W Liu, Y Xu Science 372 (6546), eabg0635, 2021 | 136 | 2021 |