Copper complexes of bis (thiosemicarbazones): from chemotherapeutics to diagnostic and therapeutic radiopharmaceuticals BM Paterson, PS Donnelly Chemical Society Reviews 40 (5), 3005-3018, 2011 | 321 | 2011 |
Comparison of macrocyclic and acyclic chelators for gallium-68 radiolabelling MI Tsionou, CE Knapp, CA Foley, CR Munteanu, A Cakebread, C Imberti, ... RSC advances 7 (78), 49586-49599, 2017 | 188 | 2017 |
Oral treatment with CuII (atsm) increases mutant SOD1 in vivo but protects motor neurons and improves the phenotype of a transgenic mouse model of amyotrophic lateral sclerosis BR Roberts, NKH Lim, EJ McAllum, PS Donnelly, DJ Hare, PA Doble, ... Journal of Neuroscience 34 (23), 8021-8031, 2014 | 188 | 2014 |
Engineering poly (ethylene glycol) particles for improved biodistribution J Cui, R De Rose, K Alt, S Alcantara, BM Paterson, K Liang, M Hu, ... ACS nano 9 (2), 1571-1580, 2015 | 164 | 2015 |
Increasing intracellular bioavailable copper selectively targets prostate cancer cells MA Cater, HB Pearson, K Wolyniec, P Klaver, M Bilandzic, BM Paterson, ... ACS chemical biology 8 (7), 1621-1631, 2013 | 149 | 2013 |
64Cu-SARTATE PET imaging of patients with neuroendocrine tumors demonstrates high tumor uptake and retention, potentially allowing prospective dosimetry for peptide receptor … RJ Hicks, P Jackson, G Kong, RE Ware, MS Hofman, DA Pattison, ... Journal of Nuclear Medicine 60 (6), 777-785, 2019 | 126 | 2019 |
Diagnostic imaging agents for Alzheimer’s disease: copper radiopharmaceuticals that target Aβ plaques JL Hickey, SC Lim, DJ Hayne, BM Paterson, JM White, VL Villemagne, ... Journal of the American Chemical Society 135 (43), 16120-16132, 2013 | 125 | 2013 |
An impaired mitochondrial electron transport chain increases retention of the hypoxia imaging agent diacetylbis (4-methylthiosemicarbazonato) copperII PS Donnelly, JR Liddell, SC Lim, BM Paterson, MA Cater, MS Savva, ... Proceedings of the National Academy of Sciences 109 (1), 47-52, 2012 | 124 | 2012 |
Tripodal tris (hydroxypyridinone) ligands for immunoconjugate PET imaging with 89 Zr 4+: comparison with desferrioxamine-B MT Ma, LK Meszaros, BM Paterson, DJ Berry, MS Cooper, Y Ma, ... Dalton transactions 44 (11), 4884-4900, 2015 | 106 | 2015 |
PET imaging of tumours with a 64 Cu labeled macrobicyclic cage amine ligand tethered to Tyr 3-octreotate BM Paterson, P Roselt, D Denoyer, C Cullinane, D Binns, W Noonan, ... Dalton Transactions 43 (3), 1386-1396, 2014 | 106 | 2014 |
Versatile New Bis(thiosemicarbazone) Bifunctional Chelators: Synthesis, Conjugation to Bombesin(7−14)-NH2, and Copper-64 Radiolabeling BM Paterson, JA Karas, DB Scanlon, JM White, PS Donnelly Inorganic chemistry 49 (4), 1884-1893, 2010 | 102 | 2010 |
Enzyme‐mediated site‐specific bioconjugation of metal complexes to proteins: Sortase‐mediated coupling of copper‐64 to a single‐chain antibody BM Paterson, K Alt, CM Jeffery, RI Price, S Jagdale, S Rigby, CC Williams, ... Angewandte Chemie 126 (24), 6229-6233, 2014 | 95 | 2014 |
Mechanisms controlling the cellular accumulation of copper bis (thiosemicarbazonato) complexes KA Price, PJ Crouch, I Volitakis, BM Paterson, SC Lim, PS Donnelly, ... Inorganic chemistry 50 (19), 9594-9605, 2011 | 91 | 2011 |
Bis (thiosemicarbazonato) Cu-64 complexes for positron emission tomography imaging of Alzheimer's disease MT Fodero-Tavoletti, VL Villemagne, BM Paterson, AR White, QX Li, ... Journal of Alzheimer's Disease 20 (1), 49-55, 2010 | 90 | 2010 |
Therapeutic effects of CuII (atsm) in the SOD1-G37R mouse model of amyotrophic lateral sclerosis EJ McAllum, NKH Lim, JL Hickey, BM Paterson, PS Donnelly, QX Li, ... Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration 14 (7-8), 586-590, 2013 | 89 | 2013 |
A copper radiopharmaceutical for diagnostic imaging of Alzheimer's disease: a bis (thiosemicarbazonato) copper (ii) complex that binds to amyloid-β plaques SC Lim, BM Paterson, MT Fodero-Tavoletti, GJ O'Keefe, R Cappai, ... Chemical communications 46 (30), 5437-5439, 2010 | 84 | 2010 |
Copper-64 labeled macrobicyclic sarcophagine coupled to a GRP receptor antagonist shows great promise for PET imaging of prostate cancer E Gourni, L Del Pozzo, E Kheirallah, C Smerling, B Waser, JC Reubi, ... Molecular pharmaceutics 12 (8), 2781-2790, 2015 | 61 | 2015 |
A versatile approach for the site‐specific modification of recombinant antibodies using a combination of enzyme‐mediated bioconjugation and click chemistry K Alt, BM Paterson, E Westein, SE Rudd, SS Poniger, S Jagdale, ... Angewandte Chemie international edition 54 (26), 7515-7519, 2015 | 61 | 2015 |
Antimicrobial effects of copper(ii) bis(thiosemicarbazonato) complexes provide new insight into their biochemical mode of action KY Djoko, BM Paterson, PS Donnelly, AG McEwan Metallomics 6 (4), 854-863, 2014 | 59 | 2014 |
Single-chain antibody conjugated to a cage amine chelator and labeled with positron-emitting copper-64 for diagnostic imaging of activated platelets K Alt, BM Paterson, K Ardipradja, C Schieber, G Buncic, B Lim, ... Molecular Pharmaceutics 11 (8), 2855-2863, 2014 | 56 | 2014 |