| Systematic immunotherapy target discovery using genome-scale in vivo CRISPR screens in CD8 T cells MB Dong, G Wang, RD Chow, L Ye, L Zhu, X Dai, JJ Park, HR Kim, ... Cell 178 (5), 1189-1204. e23, 2019 | 281 | 2019 |
| AAV-mediated direct in vivo CRISPR screen identifies functional suppressors in glioblastoma RD Chow, CD Guzman, G Wang, F Schmidt, MW Youngblood, L Ye, ... Nature neuroscience 20 (10), 1329-1341, 2017 | 247 | 2017 |
| In vivo CRISPR screening in CD8 T cells with AAV–Sleeping Beauty hybrid vectors identifies membrane targets for improving immunotherapy for glioblastoma L Ye, JJ Park, MB Dong, Q Yang, RD Chow, L Peng, Y Du, J Guo, X Dai, ... Nature biotechnology 37 (11), 1302-1313, 2019 | 170 | 2019 |
| Rational design of thermostable vaccines by engineered peptide-induced virus self-biomineralization under physiological conditions G Wang, RY Cao, R Chen, L Mo, JF Han, X Wang, X Xu, T Jiang, ... Proceedings of the National Academy of Sciences 110 (19), 7619-7624, 2013 | 163 | 2013 |
| One-step generation of modular CAR-T cells with AAV–Cpf1 X Dai, JJ Park, Y Du, HR Kim, G Wang, Y Errami, S Chen Nature Methods 16 (3), 247-254, 2019 | 155 | 2019 |
| In vitro effects of nanophase hydroxyapatite particles on proliferation and osteogenic differentiation of bone marrow‐derived mesenchymal stem cells YK Liu, GC Wang, YR Cai, HJ Ji, GS Zhou, XL Zhao, RK Tang, M Zhang Journal of Biomedical Materials Research Part A: An Official Journal of The …, 2009 | 151 | 2009 |
| A genome-scale gain-of-function CRISPR screen in CD8 T cells identifies proline metabolism as a means to enhance CAR-T therapy L Ye, JJ Park, L Peng, Q Yang, RD Chow, MB Dong, SZ Lam, J Guo, ... Cell metabolism 34 (4), 595-614. e14, 2022 | 126 | 2022 |
| Multiplexed activation of endogenous genes by CRISPRa elicits potent antitumor immunity G Wang, RD Chow, Z Bai, L Zhu, Y Errami, X Dai, MB Dong, L Ye, ... Nature Immunology 20 (11), 1494-1505, 2019 | 110 | 2019 |
| CRISPR-GEMM pooled mutagenic screening identifies KMT2D as a major modulator of immune checkpoint blockade G Wang, RD Chow, L Zhu, Z Bai, L Ye, F Zhang, PA Renauer, MB Dong, ... Cancer discovery 10 (12), 1912-1933, 2020 | 107 | 2020 |
| Human Enterovirus Nonstructural Protein 2CATPase Functions as Both an RNA Helicase and ATP-Independent RNA Chaperone H Xia, P Wang, GC Wang, J Yang, X Sun, W Wu, Y Qiu, T Shu, X Zhao, ... PLoS pathogens 11 (7), e1005067, 2015 | 106 | 2015 |
| Mapping a functional cancer genome atlas of tumor suppressors in mouse liver using AAV-CRISPR–mediated direct in vivo screening G Wang, RD Chow, L Ye, CD Guzman, X Dai, MB Dong, F Zhang, ... Science advances 4 (2), eaao5508, 2018 | 102 | 2018 |
| Calcium phosphate nanoparticles primarily induce cell necrosis through lysosomal rupture: the origination of material cytotoxicity Z Liu, Y Xiao, W Chen, Y Wang, B Wang, G Wang, X Xu, R Tang Journal of Materials Chemistry B 2 (22), 3480-3489, 2014 | 95 | 2014 |
| Antigenically shielded universal red blood cells by polydopamine-based cell surface engineering B Wang, G Wang, B Zhao, J Chen, X Zhang, R Tang Chemical science 5 (9), 3463-3468, 2014 | 89 | 2014 |
| Alleviation of high light-induced photoinhibition in cyanobacteria by artificially conferred biosilica shells W Xiong, Z Yang, H Zhai, G Wang, X Xu, W Ma, R Tang Chemical Communications 49 (68), 7525-7527, 2013 | 88 | 2013 |
| Extracellular silica nanocoat confers thermotolerance on individual cells: a case study of material-based functionalization of living cells G Wang, L Wang, P Liu, Y Yan, X Xu, R Tang ChemBioChem 11 (17), 2368-2373, 2010 | 85 | 2010 |
| Yolk–Shell Nanostructured Fe3O4@NiSiO3 for Selective Affinity and Magnetic Separation of His-Tagged Proteins Y Wang, G Wang, Y Xiao, Y Yang, R Tang ACS applied materials & interfaces 6 (21), 19092-19099, 2014 | 80 | 2014 |
| Hydrated silica exterior produced by biomimetic silicification confers viral vaccine heat-resistance G Wang, HJ Wang, H Zhou, QG Nian, Z Song, YQ Deng, X Wang, SY Zhu, ... ACS nano 9 (1), 799-808, 2015 | 75 | 2015 |
| Eggshell‐inspired biomineralization generates vaccines that do not require refrigeration G Wang, X Li, L Mo, Z Song, W Chen, Y Deng, H Zhao, E Qin, C Qin, ... Angewandte Chemie-German Edition 124 (42), 10728, 2012 | 72 | 2012 |
| In vivo profiling of metastatic double knockouts through CRISPR–Cpf1 screens RD Chow, G Wang, L Ye, A Codina, HR Kim, L Shen, MB Dong, Y Errami, ... Nature methods 16 (5), 405-408, 2019 | 65 | 2019 |
| Human IgG subclasses against enterovirus Type 71: neutralization versus antibody dependent enhancement of infection RY Cao, DY Dong, RJ Liu, JF Han, GC Wang, H Zhao, XF Li, YQ Deng, ... PLoS one 8 (5), e64024, 2013 | 65 | 2013 |