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Emad H.M. Hassanein
Emad H.M. Hassanein
Associate Professor of Pharmacology & Toxicology - Faculty of Pharmacy Al-Azhar University
Email verificata su azhar.edu.eg
Titolo
Citata da
Citata da
Anno
Coumarins as modulators of the Keap1/Nrf2/ARE signaling pathway
EHM Hassanein, AM Sayed, OE Hussein, AM Mahmoud
Oxidative Medicine and Cellular Longevity 2020 (1), 1675957, 2020
1972020
The impact of Keap1/Nrf2, P38MAPK/NF-κB and Bax/Bcl2/caspase-3 signaling pathways in the protective effects of berberine against methotrexate-induced nephrotoxicity
EHM Hassanein, AGS Shalkami, MM Khalaf, WR Mohamed, ...
Biomedicine & Pharmacotherapy 109, 47-56, 2019
1052019
New 1, 2, 4-triazole/pyrazole hybrids linked to oxime moiety as nitric oxide donor celecoxib analogs: Synthesis, cyclooxygenase inhibition anti-inflammatory, ulcerogenicity …
WAA Fadaly, YAMM Elshaier, EHM Hassanein, KRA Abdellatif
Bioorganic Chemistry 98, 103752, 2020
812020
Renoprotective effects of umbelliferone on methotrexate-induced renal injury through regulation of Nrf-2/Keap-1, P38MAPK/NF-κB, and apoptosis signaling pathways
EHM Hassanein, WR Mohamed, AGS Shalkami, MM Khalaf, ...
Food and Chemical Toxicology 116, 152-160, 2018
672018
Coenzyme Q10 protects hepatocytes from ischemia reperfusion-induced apoptosis and oxidative stress via regulation of Bax/Bcl-2/PUMA and Nrf-2/FOXO-3/Sirt-1 signaling pathways
AR Mahmoud, FEM Ali, TH Abd-Elhamid, EHM Hassanein
Tissue and Cell 60, 1-13, 2019
552019
Flavonoids-mediated SIRT1 signaling activation in hepatic disorders
AM Sayed, EHM Hassanein, SH Salem, OE Hussein, AM Mahmoud
Life sciences 259, 118173, 2020
532020
Umbelliferone attenuates gentamicin-induced renal toxicity by suppression of TLR-4/NF-κB-p65/NLRP-3 and JAK1/STAT-3 signaling pathways
EHM Hassanein, FEM Ali, MR Kozman, OAM Abd El-Ghafar
Environmental Science and Pollution Research 28, 11558-11571, 2021
492021
Reno-protective effects of ursodeoxycholic acid against gentamicin-induced nephrotoxicity through modulation of NF-κB, eNOS and caspase-3 expressions
TH Abd-Elhamid, DA Elgamal, SS Ali, FEM Ali, EHM Hassanein, ...
Cell and tissue research 374, 367-387, 2018
482018
Rebamipide potentially mitigates methotrexate‐induced nephrotoxicity via inhibition of oxidative stress and inflammation: A molecular and histochemical study
RA Elmansy, HS Seleem, AR Mahmoud, EHM Hassanein, FEM Ali
The Anatomical Record 304 (3), 647-661, 2021
452021
Edaravone and acetovanillone upregulate Nrf2 and PI3K/Akt/mTOR signaling and prevent cyclophosphamide cardiotoxicity in rats
EHM Hassanein, OAM Abd El-Ghafar, MA Ahmed, AM Sayed, ...
Drug Design, Development and Therapy, 5275-5288, 2020
452020
Ursodeoxycholic acid abrogates gentamicin-induced hepatotoxicity in rats: Role of NF-κB-p65/TNF-α, Bax/Bcl-xl/Caspase-3, and eNOS/iNOS pathways
FEM Ali, EHM Hassanein, AG Bakr, EAM El-Shoura, DA El-Gamal, ...
Life sciences 254, 117760, 2020
452020
Nephroprotective effect of umbelliferone against cisplatin‐induced kidney damage is mediated by regulation of NRF2, cytoglobin, SIRT1/FOXO‐3, and NF‐ kB‐p65 …
FEM Ali, EHM Hassanein, AH El‐Bahrawy, ZMM Omar, EK Rashwan, ...
Journal of Biochemical and Molecular Toxicology 35 (5), e22738, 2021
442021
Optimization of pyrazole-based compounds with 1, 2, 4-triazole-3-thiol moiety as selective COX-2 inhibitors cardioprotective drug candidates: Design, synthesis, cyclooxygenase …
KRA Abdellatif, EKA Abdelall, HAH Elshemy, JN Philoppes, ...
Bioorganic chemistry 114, 105122, 2021
422021
Farnesol attenuates oxidative stress and liver injury and modulates fatty acid synthase and acetyl-CoA carboxylase in high cholesterol-fed rats
MH Abukhalil, OE Hussein, M Bin-Jumah, SAM Saghir, MO Germoush, ...
Environmental Science and Pollution Research 27, 30118-30132, 2020
412020
Agomelatine prevents gentamicin nephrotoxicity by attenuating oxidative stress and TLR-4 signaling, and upregulating PPARγ and SIRT1
AM Mahmoud, OAM Abd El-Ghafar, MA Alzoghaibi, EHM Hassanein
Life Sciences 278, 119600, 2021
402021
Targeting KEAP1/Nrf2, AKT, and PPAR-γ signals as a potential protective mechanism of diosmin against gentamicin-induced nephrotoxicity
FEM Ali, AM Sayed, AH El-Bahrawy, ZMM Omar, EHM Hassanein
Life Sciences 275, 119349, 2021
402021
Roflumilast protects from cisplatin-induced testicular toxicity in male rats and enhances its cytotoxicity in prostate cancer cell line. Role of NF-κB-p65, cAMP/PKA and Nrf2/HO …
BA Abdel-Wahab, IA Walbi, HA Albarqi, FEM Ali, EHM Hassanein
Food and Chemical Toxicology 151, 112133, 2021
382021
Hepatoprotective effect of rebamipide against methotrexate-induced hepatic intoxication: role of Nrf2/GSK-3β, NF-κβ-p65/JAK1/STAT3, and PUMA/Bax/Bcl-2 signaling pathways
BA Abdel-Wahab, FEM Ali, SA Alkahtani, AM Alshabi, MH Mahnashi, ...
Immunopharmacology and Immunotoxicology 42 (5), 493-503, 2020
372020
7-hydroxycoumarin modulates Nrf2/HO-1 and microRNA-34a/SIRT1 signaling and prevents cisplatin-induced oxidative stress, inflammation, and kidney injury in rats
DH Sami, AS Soliman, AA Khowailed, EHM Hassanein, EM Kamel, ...
Life Sciences 310, 121104, 2022
342022
The role of inflammation in cadmium nephrotoxicity: NF-κB comes into view
EHM Hassanein, WR Mohamed, OS Ahmed, MM Abdel-Daim, AM Sayed
Life Sciences 308, 120971, 2022
342022
Il sistema al momento non può eseguire l'operazione. Riprova più tardi.
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