Structure− activity relationships of polymyxin antibiotics T Velkov, PE Thompson, RL Nation, J Li Journal of medicinal chemistry 53 (5), 1898-1916, 2010 | 869 | 2010 |
Pharmacology of polymyxins: new insights into an ‘old’class of antibiotics T Velkov, KD Roberts, RL Nation, PE Thompson, J Li Future microbiology 8 (6), 711-724, 2013 | 585 | 2013 |
Colistin and polymyxin B: peas in a pod, or chalk and cheese? RL Nation, T Velkov, J Li Clinical infectious diseases 59 (1), 88-94, 2014 | 353 | 2014 |
Rescuing the last-line polymyxins: achievements and challenges SC Nang, MAK Azad, T Velkov, QT Zhou, J Li, E Barker Pharmacological reviews 73 (2), 679-728, 2021 | 297 | 2021 |
A secondary mode of action of polymyxins against Gram-negative bacteria involves the inhibition of NADH-quinone oxidoreductase activity ZZ Deris, J Akter, S Sivanesan, KD Roberts, PE Thompson, RL Nation, ... The Journal of antibiotics 67 (2), 147-151, 2014 | 281 | 2014 |
The rise and spread of mcr plasmid-mediated polymyxin resistance SC Nang, J Li, T Velkov Critical reviews in microbiology 45 (2), 131-161, 2019 | 245 | 2019 |
Allosteric folding correction of F508del and rare CFTR mutants by elexacaftor-tezacaftor-ivacaftor (Trikafta) combination G Veit, A Roldan, MA Hancock, DF Da Fonte, H Xu, M Hussein, S Frenkiel, ... JCI insight 5 (18), 2020 | 220 | 2020 |
Pharmacokinetics/pharmacodynamics of colistin and polymyxin B: are we there yet? TB Tran, T Velkov, RL Nation, A Forrest, BT Tsuji, PJ Bergen, J Li International journal of antimicrobial agents 48 (6), 592-597, 2016 | 203 | 2016 |
Antimicrobial activity and toxicity of the major lipopeptide components of polymyxin B and colistin: last-line antibiotics against multidrug-resistant Gram-negative bacteria KD Roberts, MAK Azad, J Wang, AS Horne, PE Thompson, RL Nation, ... ACS infectious diseases 1 (11), 568-575, 2015 | 166 | 2015 |
The natural product curcumin as an antibacterial agent: Current achievements and problems C Dai, J Lin, H Li, Z Shen, Y Wang, T Velkov, J Shen Antioxidants 11 (3), 459, 2022 | 160 | 2022 |
Chloroquine ameliorates carbon tetrachloride-induced acute liver injury in mice via the concomitant inhibition of inflammation and induction of apoptosis C Dai, X Xiao, D Li, S Tun, Y Wang, T Velkov, S Tang Cell Death & Disease 9 (12), 1164, 2018 | 155 | 2018 |
Probing the penetration of antimicrobial polymyxin lipopeptides into gram-negative bacteria ZZ Deris, JD Swarbrick, KD Roberts, MAK Azad, J Akter, AS Horne, ... Bioconjugate chemistry 25 (4), 750-760, 2014 | 152 | 2014 |
Head and flagella subcompartmental proteomic analysis of human spermatozoa MA Baker, N Naumovski, L Hetherington, A Weinberg, T Velkov, RJ Aitken Proteomics 13 (1), 61-74, 2013 | 143 | 2013 |
Teaching ‘old’polymyxins new tricks: new-generation lipopeptides targeting gram-negative ‘superbugs’ T Velkov, KD Roberts, RL Nation, J Wang, PE Thompson, J Li ACS chemical biology 9 (5), 1172-1177, 2014 | 140 | 2014 |
T-2 toxin neurotoxicity: role of oxidative stress and mitochondrial dysfunction C Dai, X Xiao, F Sun, Y Zhang, D Hoyer, J Shen, S Tang, T Velkov Archives of Toxicology 93, 3041-3056, 2019 | 130 | 2019 |
Lycopene attenuates colistin-induced nephrotoxicity in mice via activation of the Nrf2/HO-1 pathway C Dai, S Tang, S Deng, S Zhang, Y Zhou, T Velkov, J Li, X Xiao Antimicrobial agents and chemotherapy 59 (1), 579-585, 2015 | 130 | 2015 |
Polymyxin B induces apoptosis in kidney proximal tubular cells MAK Azad, BA Finnin, A Poudyal, K Davis, J Li, PA Hill, RL Nation, ... Antimicrobial agents and chemotherapy 57 (9), 4329-4335, 2013 | 126 | 2013 |
The combination of colistin and doripenem is synergistic against Klebsiella pneumoniae at multiple inocula and suppresses colistin resistance in an in vitro pharmacokinetic … ZZ Deris, HH Yu, K Davis, RL Soon, J Jacob, CK Ku, A Poudyal, ... Antimicrobial agents and chemotherapy 56 (10), 5103-5112, 2012 | 120 | 2012 |
The antimicrobial activity of cannabinoids JA Karas, LJM Wong, OKA Paulin, AC Mazeh, MH Hussein, J Li, T Velkov Antibiotics 9 (7), 406, 2020 | 115 | 2020 |
Inhaled anti-infective chemotherapy for respiratory tract infections: successes, challenges and the road ahead T Velkov, NA Rahim, QT Zhou, HK Chan, J Li Advanced drug delivery reviews 85, 65-82, 2015 | 113 | 2015 |