| Saturated fatty acids produce an inflammatory response predominantly through the activation of TLR4 signaling in hypothalamus: implications for the pathogenesis of obesity M Milanski, G Degasperi, A Coope, J Morari, R Denis, DE Cintra, ... Journal of Neuroscience 29 (2), 359-370, 2009 | 1257 | 2009 |
| The effects of aerobic, resistance, and combined exercise on metabolic control, inflammatory markers, adipocytokines, and muscle insulin signaling in patients with type 2 … MLMP Jorge, VN de Oliveira, NM Resende, LF Paraiso, A Calixto, ... Metabolism 60 (9), 1244-1252, 2011 | 664 | 2011 |
| High-fat diet induces apoptosis of hypothalamic neurons JC Moraes, A Coope, J Morari, DE Cintra, EA Roman, JR Pauli, ... PloS one 4 (4), e5045, 2009 | 518 | 2009 |
| TNF-α mediates PKR-dependent memory impairment and brain IRS-1 inhibition induced by Alzheimer’s β-amyloid oligomers in mice and monkeys MV Lourenco, JR Clarke, RL Frozza, TR Bomfim, L Forny-Germano, ... Cell metabolism 18 (6), 831-843, 2013 | 425 | 2013 |
| Unsaturated fatty acids revert diet-induced hypothalamic inflammation in obesity DE Cintra, ER Ropelle, JC Moraes, JR Pauli, J Morari, CT de Souza, ... PloS one 7 (1), e30571, 2012 | 423 | 2012 |
| Modulation of gut microbiota by antibiotics improves insulin signalling in high-fat fed mice BM Carvalho, D Guadagnini, DML Tsukumo, AA Schenka, P Latuf-Filho, ... Diabetologia 55, 2823-2834, 2012 | 360 | 2012 |
| Metformin amplifies chemotherapy-induced AMPK activation and antitumoral growth GZ Rocha, MM Dias, ER Ropelle, F Osório-Costa, FA Rossato, ... Clinical cancer research 17 (12), 3993-4005, 2011 | 359 | 2011 |
| S-nitrosation of the insulin receptor, insulin receptor substrate 1, and protein kinase B/Akt: a novel mechanism of insulin resistance MA Carvalho-Filho, M Ueno, SM Hirabara, AB Seabra, JBC Carvalheira, ... Diabetes 54 (4), 959-967, 2005 | 346 | 2005 |
| Topical insulin accelerates wound healing in diabetes by enhancing the AKT and ERK pathways: a double-blind placebo-controlled clinical trial MHM Lima, AM Caricilli, LL de Abreu, EP Araújo, FF Pelegrinelli, ... PloS one 7 (5), e36974, 2012 | 254 | 2012 |
| Vias de sinalização da insulina JBC Carvalheira, HG Zecchin, MJA Saad Arquivos Brasileiros de Endocrinologia & Metabologia 46, 419-425, 2002 | 240 | 2002 |
| Regulation of insulin signalling by hyperinsulinaemia: role of IRS-1/2 serine phosphorylation and the mTOR/p70 S6K pathway M Ueno, JBC Carvalheira, RC Tambascia, RMN Bezerra, ME Amaral, ... Diabetologia 48, 506-518, 2005 | 237 | 2005 |
| Low-grade hypothalamic inflammation leads to defective thermogenesis, insulin resistance, and impaired insulin secretion AP Arruda, M Milanski, A Coope, AS Torsoni, E Ropelle, DP Carvalho, ... Endocrinology 152 (4), 1314-1326, 2011 | 228 | 2011 |
| Alzheimer‐associated Aβ oligomers impact the central nervous system to induce peripheral metabolic deregulation JR Clarke, NM Lyra e Silva, CP Figueiredo, RL Frozza, JH Ledo, ... EMBO molecular medicine 7 (2), 190-210, 2015 | 220 | 2015 |
| Reversal of diet‐induced insulin resistance with a single bout of exercise in the rat: the role of PTP1B and IRS‐1 serine phosphorylation ER Ropelle, JR Pauli, PO Prada, CT De Souza, PK Picardi, MC Faria, ... The Journal of physiology 577 (3), 997-1007, 2006 | 218 | 2006 |
| Selective impairment of insulin signalling in the hypothalamus of obese Zucker rats JBC Carvalheira, EB Ribeiro, EP Araujo, RB Guimaraes, MM Telles, ... Diabetologia 46, 1629-1640, 2003 | 202 | 2003 |
| Cross‐Talk between the Insulin and Leptin Signaling Systems in Rat Hypothalamus** JBC Carvalheira, MA Torsoni, M Ueno, ME Amaral, EP Araújo, LA Velloso, ... Obesity research 13 (1), 48-57, 2005 | 188 | 2005 |
| Insulin modulates leptin-induced STAT3 activation in rat hypothalamus JBC Carvalheira, RMP Siloto, I Ignacchitti, SL Brenelli, CRO Carvalho, ... FEBS letters 500 (3), 119-124, 2001 | 184 | 2001 |
| Endurance training improves responsiveness to insulin and modulates insulin signal transduction through the phosphatidylinositol 3-kinase/Akt-1 pathway E Luciano, EM Carneiro, CRO Carvalho, JBC Carvalheira, SB Peres, ... European journal of endocrinology 147 (1), 149-157, 2002 | 183 | 2002 |
| Inhibition of TLR2 expression improves insulin sensitivity and signaling in muscle and white adipose tissue of mice fed a high-fat diet AM Caricilli, PH Nascimento, JR Pauli, DML Tsukumo, LA Velloso, ... J Endocrinol 199 (3), 399-406, 2008 | 167 | 2008 |
| Novel signal transduction pathway for luteinizing hormone and its interaction with insulin: activation of Janus kinase/signal transducer and activator of transcription and … CRO Carvalho, JBC Carvalheira, MHM Lima, SF Zimmerman, ... Endocrinology 144 (2), 638-647, 2003 | 163 | 2003 |
Maria Carolina Santos MendesResearcher, Faculdade de Ciências Médicas