| HIV-1 evades innate immune recognition through specific cofactor recruitment J Rasaiyaah, CP Tan, AJ Fletcher, AJ Price, C Blondeau, L Hilditch, ... Nature 503 (7476), 402-405, 2013 | 548 | 2013 |
| Small‐angle scattering for structural biology—Expanding the frontier while avoiding the pitfalls DA Jacques, J Trewhella Protein science 19 (4), 642-657, 2010 | 525 | 2010 |
| Host cofactors and pharmacologic ligands share an essential interface in HIV-1 capsid that is lost upon disassembly AJ Price, DA Jacques, WA McEwan, AJ Fletcher, S Essig, JW Chin, ... PLoS pathogens 10 (10), e1004459, 2014 | 300 | 2014 |
| HIV-1 uses dynamic capsid pores to import nucleotides and fuel encapsidated DNA synthesis DA Jacques, WA McEwan, L Hilditch, AJ Price, GJ Towers, LC James Nature 536 (7616), 349-353, 2016 | 258 | 2016 |
| SARS-CoV-2 proteases PLpro and 3CLpro cleave IRF3 and critical modulators of inflammatory pathways (NLRP12 and TAB1): implications for disease presentation across species M Moustaqil, E Ollivier, HP Chiu, S Van Tol, P Rudolffi-Soto, C Stevens, ... Emerging microbes & infections 10 (1), 178-195, 2021 | 238 | 2021 |
| 2017 publication guidelines for structural modelling of small-angle scattering data from biomolecules in solution: an update J Trewhella, AP Duff, D Durand, F Gabel, JM Guss, WA Hendrickson, ... Acta Crystallographica Section D: Structural Biology 73 (9), 710-728, 2017 | 230 | 2017 |
| IP6 is an HIV pocket factor that prevents capsid collapse and promotes DNA synthesis DL Mallery, CL Marquez, WA McEwan, CF Dickson, DA Jacques, ... Elife 7, e35335, 2018 | 177 | 2018 |
| Publication guidelines for structural modelling of small-angle scattering data from biomolecules in solution DA Jacques, JM Guss, DI Svergun, J Trewhella Acta Crystallographica Section D: Biological Crystallography 68 (6), 620-626, 2012 | 161 | 2012 |
| Kinetics of HIV-1 capsid uncoating revealed by single-molecule analysis CL Marquez, D Lau, J Walsh, V Shah, C McGuinness, A Wong, ... Elife 7, e34772, 2018 | 114 | 2018 |
| The structure of the KinA-Sda complex suggests an allosteric mechanism of histidine kinase inhibition AE Whitten, DA Jacques, B Hammouda, T Hanley, GF King, JM Guss, ... Journal of molecular biology 368 (2), 407-420, 2007 | 95 | 2007 |
| Structural basis for hemoglobin capture by Staphylococcus aureus cell-surface protein, IsdH KK Kumar, DA Jacques, G Pishchany, T Caradoc-Davies, T Spirig, ... Journal of Biological Chemistry 286 (44), 38439-38447, 2011 | 73 | 2011 |
| Target-induced clustering activates Trim-Away of pathogens and proteins J Zeng, AF Santos, AS Mukadam, M Osswald, DA Jacques, CF Dickson, ... Nature structural & molecular biology 28 (3), 278-289, 2021 | 68 | 2021 |
| Structure of the Hemoglobin-IsdH Complex Reveals the Molecular Basis of Iron Capture by Staphylococcus aureus*♦ CF Dickson, KK Kumar, DA Jacques, GR Malmirchegini, T Spirig, ... Journal of Biological Chemistry 289 (10), 6728-6738, 2014 | 52 | 2014 |
| New insights into DNA recognition by zinc fingers revealed by structural analysis of the oncoprotein ZNF217 M Vandevenne, DA Jacques, C Artuz, CD Nguyen, AHY Kwan, DJ Segal, ... Journal of Biological Chemistry 288 (15), 10616-10627, 2013 | 52 | 2013 |
| Intracellular immunity: finding the enemy within—how cells recognize and respond to intracellular pathogens JCH Tam, DA Jacques Journal of leukocyte biology 96 (2), 233-244, 2014 | 48 | 2014 |
| Evasion of cGAS and TRIM5 defines pandemic HIV L Zuliani-Alvarez, ML Govasli, J Rasaiyaah, C Monit, SO Perry, ... Nature microbiology 7 (11), 1762-1776, 2022 | 45* | 2022 |
| A lysine ring in HIV capsid pores coordinates IP6 to drive mature capsid assembly N Renner, DL Mallery, KMR Faysal, W Peng, DA Jacques, T Böcking, ... PLoS pathogens 17 (2), e1009164, 2021 | 40 | 2021 |
| The HIV capsid mimics karyopherin engagement of FG-nucleoporins CF Dickson, S Hertel, AJ Tuckwell, N Li, J Ruan, SC Al-Izzi, N Ariotti, ... Nature 626 (8000), 836-842, 2024 | 39* | 2024 |
| A structural basis for the regulation of the LIM-homeodomain protein islet 1 (Isl1) by intra-and intermolecular interactions MS Gadd, DA Jacques, I Nisevic, VJ Craig, AH Kwan, JM Guss, ... Journal of Biological Chemistry 288 (30), 21924-21935, 2013 | 38 | 2013 |
| Histidine kinase regulation by a cyclophilin-like inhibitor DA Jacques, DB Langley, CM Jeffries, KA Cunningham, WF Burkholder, ... Journal of molecular biology 384 (2), 422-435, 2008 | 36 | 2008 |
Leo JamesMRC Laboratory of Molecular BiologyEmail verificata su mrc-lmb.cam.ac.uk
