EGF receptor is required for KRAS-induced pancreatic tumorigenesis CM Ardito, BM Grüner, KK Takeuchi, C Lubeseder-Martellato, ... Cancer cell 22 (3), 304-317, 2012 | 567 | 2012 |
Nfib promotes metastasis through a widespread increase in chromatin accessibility SK Denny, D Yang, CH Chuang, JJ Brady, JS Lim, BM Grüner, SH Chiou, ... Cell 166 (2), 328-342, 2016 | 369 | 2016 |
Pancreatic cancer modeling using retrograde viral vector delivery and in vivo CRISPR/Cas9-mediated somatic genome editing SH Chiou, IP Winters, J Wang, S Naranjo, C Dudgeon, FB Tamburini, ... Genes & development 29 (14), 1576-1585, 2015 | 284 | 2015 |
Molecular definition of a metastatic lung cancer state reveals a targetable CD109–Janus kinase–Stat axis CH Chuang, PG Greenside, ZN Rogers, JJ Brady, D Yang, RK Ma, ... Nature medicine 23 (3), 291-300, 2017 | 163 | 2017 |
An in vivo multiplexed small-molecule screening platform BM Grüner, CJ Schulze, D Yang, D Ogasawara, MM Dix, ZN Rogers, ... Nature methods 13 (10), 883-889, 2016 | 69 | 2016 |
BLIMP1 induces transient metastatic heterogeneity in pancreatic cancer SH Chiou, VI Risca, GX Wang, D Yang, BM Grüner, AS Kathiria, RK Ma, ... Cancer discovery 7 (10), 1184-1199, 2017 | 68 | 2017 |
MALDI Imaging Mass Spectrometry for In Situ Proteomic Analysis of Preneoplastic Lesions in Pancreatic Cancer BM Grüner, H Hahne, PK Mazur, M Trajkovic-Arsic, S Maier, I Esposito, ... PloS one 7 (6), e39424, 2012 | 66 | 2012 |
Identification of Epidermal Pdx1 Expression Discloses Different Roles of Notch1 and Notch2 in Murine KrasG12D-Induced Skin Carcinogenesis In Vivo PK Mazur, BM Grüner, H Nakhai, B Sipos, U Zimber-Strobl, LJ Strobl, ... PloS one 5 (10), e13578, 2010 | 59 | 2010 |
Decrypting drug actions and protein modifications by dose-and time-resolved proteomics J Zecha, FP Bayer, S Wiechmann, J Woortman, N Berner, J Müller, ... Science 380 (6640), 93-101, 2023 | 56 | 2023 |
Axon-like protrusions promote small cell lung cancer migration and metastasis D Yang, F Qu, H Cai, CH Chuang, JS Lim, N Jahchan, BM Grüner, ... Elife 8, e50616, 2019 | 55 | 2019 |
Altered mitochondria functionality defines a metastatic cell state in lung cancer and creates an exploitable vulnerability CH Chuang, M Dorsch, P Dujardin, S Silas, K Ueffing, JM Hölken, D Yang, ... Cancer research 81 (3), 567-579, 2021 | 41 | 2021 |
HER2 mediates clinical resistance to the KRASG12C inhibitor sotorasib, which is overcome by co-targeting SHP2 CSL Ho, AI Tüns, HU Schildhaus, M Wiesweg, BM Grüner, B Hegedus, ... European Journal of Cancer 159, 16-23, 2021 | 40 | 2021 |
Statins affect cancer cell plasticity with distinct consequences for tumor progression and metastasis M Dorsch, M Kowalczyk, M Planque, G Heilmann, S Urban, P Dujardin, ... Cell Reports 37 (8), 2021 | 38 | 2021 |
Functional screening identifies aryl hydrocarbon receptor as suppressor of lung cancer metastasis S Nothdurft, C Thumser-Henner, F Breitenbücher, RA Okimoto, M Dorsch, ... Oncogenesis 9 (11), 102, 2020 | 37 | 2020 |
Hmga2 is dispensable for pancreatic cancer development, metastasis, and therapy resistance SH Chiou, M Dorsch, E Kusch, S Naranjo, MM Kozak, AC Koong, ... Scientific reports 8 (1), 14008, 2018 | 33 | 2018 |
Modeling therapy response and spatial tissue distribution of erlotinib in pancreatic cancer BM Grüner, I Winkelmann, A Feuchtinger, N Sun, B Balluff, N Teichmann, ... Molecular cancer therapeutics 15 (5), 1145-1152, 2016 | 30 | 2016 |
An inducible Tet-Off-H2B-GFP lentiviral reporter vector for detection and in vivo isolation of label-retaining cells B Falkowska-Hansen, J Kollar, BM Grüner, M Schanz, P Boukamp, ... Experimental cell research 316 (11), 1885-1895, 2010 | 27 | 2010 |
Identification of a Ninein (NIN) mutation in a family with spondyloepimetaphyseal dysplasia with joint laxity (leptodactylic type)-like phenotype M Grosch, B Grüner, S Spranger, AM Stütz, T Rausch, JO Korbel, ... Matrix Biology 32 (7-8), 387-392, 2013 | 20 | 2013 |
Cancer cells stock up in lymph vessels to survive BM Grüner, SM Fendt Nature 585 (7823), 36-37, 2020 | 13 | 2020 |
Unraveling tumor heterogeneity by using DNA barcoding technologies to develop personalized treatment strategies in advanced-stage PDAC P Dujardin, AK Baginska, S Urban, BM Grüner Cancers 13 (16), 4187, 2021 | 7 | 2021 |