| Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders DJ Baker, T Wijshake, T Tchkonia, NK LeBrasseur, BG Childs, ... Nature 479 (7372), 232-236, 2011 | 3981 | 2011 |
| Low-density lipoproteins cause atherosclerotic cardiovascular disease. 1. Evidence from genetic, epidemiologic, and clinical studies. A consensus statement from the European … BA Ference, HN Ginsberg, I Graham, KK Ray, CJ Packard, E Bruckert, ... European heart journal 38 (32), 2459-2472, 2017 | 3822 | 2017 |
| Low-density lipoproteins cause atherosclerotic cardiovascular disease: pathophysiological, genetic, and therapeutic insights: a consensus statement from the European … J Boren, MJ Chapman, RM Krauss, CJ Packard, JF Bentzon, CJ Binder, ... European heart journal 41 (24), 2313-2330, 2020 | 1350 | 2020 |
| Chronic inflammation induces telomere dysfunction and accelerates ageing in mice D Jurk, C Wilson, JF Passos, F Oakley, C Correia-Melo, L Greaves, ... Nature communications 5 (1), 4172, 2014 | 831 | 2014 |
| Identification of a new copper metabolism gene by positional cloning in a purebred dog population B van De Sluis, J Rothuizen, PL Pearson, BA van Oost, C Wijmenga Human molecular genetics 11 (2), 165-173, 2002 | 450 | 2002 |
| A proinflammatory gut microbiota increases systemic inflammation and accelerates atherosclerosis E Brandsma, NJ Kloosterhuis, M Koster, DC Dekker, MJJ Gijbels, ... Circulation research 124 (1), 94-100, 2019 | 339 | 2019 |
| Increased expression of BubR1 protects against aneuploidy and cancer and extends healthy lifespan DJ Baker, MM Dawlaty, T Wijshake, KB Jeganathan, L Malureanu, ... Nature cell biology 15 (1), 96-102, 2013 | 332 | 2013 |
| A novel role for XIAP in copper homeostasis through regulation of MURR1 E Burstein, L Ganesh, RD Dick, B van De Sluis, JC Wilkinson, LWJ Klomp, ... The EMBO journal 23 (1), 244-254, 2004 | 282 | 2004 |
| Human copper transporter 2 is localized in late endosomes and lysosomes and facilitates cellular copper uptake DE Folmer, HEM Malingré, AEM Klomp, M Merkx, R Berger, LWJ Klomp The Biochemical journal 407 (Pt 1), 49, 2007 | 249 | 2007 |
| Two-step senescence-focused cancer therapies CJ Sieben, I Sturmlechner, B van de Sluis, JM van Deursen Trends in cell biology 28 (9), 723-737, 2018 | 247 | 2018 |
| COMMD1 is linked to the WASH complex and regulates endosomal trafficking of the copper transporter ATP7A CA Phillips-Krawczak, A Singla, P Starokadomskyy, Z Deng, DG Osborne, ... Molecular biology of the cell 26 (1), 91-103, 2015 | 230 | 2015 |
| IL-1β and TGFβ2 synergistically induce endothelial to mesenchymal transition in an NFκB-dependent manner M Maleszewska, JRAJ Moonen, N Huijkman, B van de Sluis, G Krenning, ... Immunobiology, 2012 | 230 | 2012 |
| CCC-and WASH-mediated endosomal sorting of LDLR is required for normal clearance of circulating LDL P Bartuzi, DD Billadeau, R Favier, S Rong, D Dekker, A Fedoseienko, ... Nature communications 7 (1), 1-11, 2016 | 211 | 2016 |
| The NADPH oxidase Nox4 has anti-atherosclerotic functions C Schürmann, F Rezende, C Kruse, Y Yasar, O Löwe, C Fork, ... European heart journal 36 (48), 3447-3456, 2015 | 193 | 2015 |
| Distinct Wilson’s disease mutations in ATP7B are associated with enhanced binding to COMMD1 and reduced stability of ATP7B P de Bie, B van de Sluis, E Burstein, PVE van de Berghe, P Muller, ... Gastroenterology 133 (4), 1316-1326, 2007 | 190 | 2007 |
| The S/T-rich motif in the DNAJB6 chaperone delays polyglutamine aggregation and the onset of disease in a mouse model V Kakkar, C Månsson, EP de Mattos, S Bergink, M van Der Zwaag, ... Molecular cell 62 (2), 272-283, 2016 | 183 | 2016 |
| The ubiquitously expressed MURR1 protein is absent in canine copper toxicosis AEM Klomp, B van de Sluis, LWJ Klomp, C Wijmenga Journal of hepatology 39 (5), 703-709, 2003 | 180 | 2003 |
| COMMD1 disrupts HIF-1α/β dimerization and inhibits human tumor cell invasion B Van De Sluis, X Mao, Y Zhai, AJ Groot, JF Vermeulen, E Van Der Wall, ... The Journal of clinical investigation 120 (6), 2119-2130, 2010 | 159 | 2010 |
| Tuning NF-κB activity: a touch of COMMD proteins P Bartuzi, MH Hofker, B van de Sluis Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1832 (12 …, 2013 | 158 | 2013 |
| Increased activity of hypoxia-inducible factor 1 is associated with early embryonic lethality in Commd1 null mice B van de Sluis, P Muller, K Duran, A Chen, AJ Groot, LW Klomp, PP Liu, ... Molecular and Cellular Biology, 2007 | 148 | 2007 |
Cisca Wijmenga, PhDERC advanced investigator; Professor of Human Genetics, Dept Genetics (MGE), UMCG, Groningen, theEmail verificata su umcg.nl
