| Childhood cerebellar tumours mirror conserved fetal transcriptional programs MC Vladoiu, I El-Hamamy, LK Donovan, H Farooq, BL Holgado, ... Nature 572 (7767), 67-73, 2019 | 419 | 2019 |
| H3K27M induces defective chromatin spread of PRC2-mediated repressive H3K27me2/me3 and is essential for glioma tumorigenesis AS Harutyunyan, B Krug, H Chen, S Papillon-Cavanagh, M Zeinieh, ... Nature communications 10 (1), 1262, 2019 | 320 | 2019 |
| H3. 3K27M cooperates with Trp53 loss and PDGFRA gain in mouse embryonic neural progenitor cells to induce invasive high-grade gliomas M Pathania, N De Jay, N Maestro, AS Harutyunyan, J Nitarska, ... Cancer cell 32 (5), 684-700. e9, 2017 | 266 | 2017 |
| Comment on “Widespread RNA and DNA Sequence Differences in the Human Transcriptome” CL Kleinman, J Majewski Science 335, 1302-c, 2012 | 251* | 2012 |
| Stalled developmental programs at the root of pediatric brain tumors S Jessa, A Blanchet-Cohen, B Krug, M Vladoiu, M Coutelier, D Faury, ... Nature genetics 51 (12), 1702-1713, 2019 | 250 | 2019 |
| Fusion of TTYH1 with the C19MC microRNA cluster drives expression of a brain-specific DNMT3B isoform in the embryonal brain tumor ETMR CL Kleinman, N Gerges, S Papillon-Cavanagh, P Sin-Chan, ... Nature genetics 46 (1), 39-44, 2014 | 224 | 2014 |
| Pervasive H3K27 acetylation leads to ERV expression and a therapeutic vulnerability in H3K27M gliomas B Krug, N De Jay, AS Harutyunyan, S Deshmukh, DM Marchione, ... Cancer cell 35 (5), 782-797. e8, 2019 | 197 | 2019 |
| Polyadenylation-dependent control of long noncoding RNA expression by the poly (A)-binding protein nuclear 1 YB Beaulieu, CL Kleinman, AM Landry-Voyer, J Majewski, F Bachand PLoS genetics 8 (11), e1003078, 2012 | 182 | 2012 |
| A pseudouridine synthase module is essential for mitochondrial protein synthesis and cell viability H Antonicka, K Choquet, ZY Lin, AC Gingras, CL Kleinman, ... EMBO reports 18 (1), 28-38, 2017 | 170 | 2017 |
| RNA sequencing reveals the role of splicing polymorphisms in regulating human gene expression E Lalonde, KCH Ha, Z Wang, A Bemmo, CL Kleinman, T Kwan, ... Genome research 21 (4), 545-554, 2011 | 157 | 2011 |
| Macrocyclic lactone resistance in Dirofilaria immitis: failure of heartworm preventives and investigation of genetic markers for resistance C Bourguinat, ACY Lee, R Lizundia, BL Blagburn, JL Liotta, MS Kraus, ... Veterinary parasitology 210 (3-4), 167-178, 2015 | 151 | 2015 |
| Histone H3. 3G34-mutant interneuron progenitors co-opt PDGFRA for gliomagenesis CCL Chen, S Deshmukh, S Jessa, D Hadjadj, V Lisi, AF Andrade, D Faury, ... Cell 183 (6), 1617-1633. e22, 2020 | 144 | 2020 |
| Failure of human rhombic lip differentiation underlies medulloblastoma formation LD Hendrikse, P Haldipur, O Saulnier, J Millman, AH Sjoboen, ... Nature 609 (7929), 1021-1028, 2022 | 114 | 2022 |
| Dual targeting of polyamine synthesis and uptake in diffuse intrinsic pontine gliomas A Khan, LD Gamble, DH Upton, C Ung, DMT Yu, A Ehteda, R Pandher, ... Nature communications 12 (1), 971, 2021 | 100 | 2021 |
| A C19MC-LIN28A-MYCN oncogenic circuit driven by hijacked super-enhancers is a distinct therapeutic vulnerability in ETMRs: a lethal brain tumor P Sin-Chan, I Mumal, T Suwal, B Ho, X Fan, I Singh, Y Du, M Lu, N Patel, ... Cancer cell 36 (1), 51-67. e7, 2019 | 91 | 2019 |
| A targetable EGFR-dependent tumor-initiating program in breast cancer P Savage, A Blanchet-Cohen, T Revil, D Badescu, SMI Saleh, YC Wang, ... Cell reports 21 (5), 1140-1149, 2017 | 84 | 2017 |
| TRPV4 and KRAS and FGFR1 gain-of-function mutations drive giant cell lesions of the jaw CC Gomes, T Gayden, A Bajic, OF Harraz, J Pratt, H Nikbakht, E Bareke, ... Nature communications 9 (1), 4572, 2018 | 83 | 2018 |
| ZFTA–RELA dictates oncogenic transcriptional programs to drive aggressive supratentorial ependymoma A Arabzade, Y Zhao, S Varadharajan, HC Chen, S Jessa, B Rivas, ... Cancer discovery 11 (9), 2200-2215, 2021 | 81 | 2021 |
| PRMT5 is essential for B cell development and germinal center dynamics LC Litzler, A Zahn, AP Meli, S Hébert, AM Patenaude, SP Methot, ... Nature communications 10 (1), 22, 2019 | 81 | 2019 |
| SWI/SNF-compromised cancers are susceptible to bromodomain inhibitors T Shorstova, M Marques, J Su, J Johnston, CL Kleinman, N Hamel, ... Cancer research 79 (10), 2761-2774, 2019 | 72 | 2019 |
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