Wnt and TGF-β signaling are required for the induction of an in vitro model of primitive streak formation using embryonic stem cells P Gadue, TL Huber, PJ Paddison, GM Keller Proceedings of the National Academy of Sciences 103 (45), 16806-16811, 2006 | 700 | 2006 |
BMP-4 is required for hepatic specification of mouse embryonic stem cell–derived definitive endoderm V Gouon-Evans, L Boussemart, P Gadue, D Nierhoff, CI Koehler, A Kubo, ... Nature biotechnology 24 (11), 1402-1411, 2006 | 529 | 2006 |
Requirement of the RNA editing deaminase ADAR1 gene for embryonic erythropoiesis Q Wang, J Khillan, P Gadue, K Nishikura Science 290 (5497), 1765-1768, 2000 | 515 | 2000 |
Generation of transgene-free lung disease-specific human induced pluripotent stem cells using a single excisable lentiviral stem cell cassette A Somers, JC Jean, CA Sommer, A Omari, CC Ford, JA Mills, L Ying, ... Stem cells 28 (10), 1728-1740, 2010 | 500 | 2010 |
Identification and targeting of the ROSA26 locus in human embryonic stem cells S Irion, H Luche, P Gadue, HJ Fehling, M Kennedy, G Keller Nature biotechnology 25 (12), 1477-1482, 2007 | 423 | 2007 |
Wnt, activin, and BMP signaling regulate distinct stages in the developmental pathway from embryonic stem cells to blood MC Nostro, X Cheng, GM Keller, P Gadue Cell stem cell 2 (1), 60-71, 2008 | 406 | 2008 |
Human definitive haemogenic endothelium and arterial vascular endothelium represent distinct lineages A Ditadi, CM Sturgeon, J Tober, G Awong, M Kennedy, AD Yzaguirre, ... Nature cell biology 17 (5), 580-591, 2015 | 345 | 2015 |
Self-renewing endodermal progenitor lines generated from human pluripotent stem cells X Cheng, L Ying, L Lu, AM Galvão, JA Mills, HC Lin, DN Kotton, SS Shen, ... Cell stem cell 10 (4), 371-384, 2012 | 312 | 2012 |
The Src family tyrosine kinase Fyn regulates natural killer T cell development P Gadue, N Morton, PL Stein The Journal of experimental medicine 190 (8), 1189-1196, 1999 | 240 | 1999 |
A unique role for Fyn in CNS myelination BR Sperber, EA Boyle-Walsh, MJ Engleka, P Gadue, AC Peterson, ... Journal of Neuroscience 21 (6), 2039-2047, 2001 | 237 | 2001 |
Foxa2 and H2A. Z mediate nucleosome depletion during embryonic stem cell differentiation Z Li, P Gadue, K Chen, Y Jiao, G Tuteja, J Schug, W Li, KH Kaestner Cell 151 (7), 1608-1616, 2012 | 236 | 2012 |
NK T cell precursors exhibit differential cytokine regulation and require Itk for efficient maturation P Gadue, PL Stein The Journal of Immunology 169 (5), 2397-2406, 2002 | 212 | 2002 |
Transcriptional competence and the active marking of tissue-specific enhancers by defined transcription factors in embryonic and induced pluripotent stem cells J Xu, JA Watts, SD Pope, P Gadue, M Kamps, K Plath, KS Zaret, ST Smale Genes & development 23 (24), 2824-2838, 2009 | 209 | 2009 |
Germ layer induction from embryonic stem cells P Gadue, TL Huber, MC Nostro, S Kattman, GM Keller Experimental hematology 33 (9), 955-964, 2005 | 193 | 2005 |
The aryl hydrocarbon receptor directs hematopoietic progenitor cell expansion and differentiation BW Smith, SS Rozelle, A Leung, J Ubellacker, A Parks, SK Nah, D French, ... Blood, The Journal of the American Society of Hematology 122 (3), 376-385, 2013 | 188 | 2013 |
Mesoderm and definitive endoderm cell populations G Keller, P Gadue US Patent App. 11/165,930, 2006 | 151 | 2006 |
The mer receptor tyrosine kinase: expression and function suggest a role in innate immunity EM Behrens, P Gadue, S Gong, S Garrett, PL Stein, PL Cohen European journal of immunology 33 (8), 2160-2167, 2003 | 150 | 2003 |
Understanding platelet generation from megakaryocytes: implications for in vitro–derived platelets X Sim, M Poncz, P Gadue, DL French Blood, The Journal of the American Society of Hematology 127 (10), 1227-1233, 2016 | 138 | 2016 |
Trisomy 21-associated defects in human primitive hematopoiesis revealed through induced pluripotent stem cells ST Chou, M Byrska-Bishop, JM Tober, Y Yao, D VanDorn, JB Opalinska, ... Proceedings of the National Academy of Sciences 109 (43), 17573-17578, 2012 | 138 | 2012 |
GATA6 plays an important role in the induction of human definitive endoderm, development of the pancreas, and functionality of pancreatic β cells A Tiyaboonchai, FL Cardenas-Diaz, L Ying, JA Maguire, X Sim, ... Stem cell reports 8 (3), 589-604, 2017 | 135 | 2017 |