Single-molecule visualization of DNA G-quadruplex formation in live cells M Di Antonio, A Ponjavic, A Radzevičius, RT Ranasinghe, M Catalano, ... Nature chemistry 12 (9), 832-837, 2020 | 301 | 2020 |
Poly (ADP-Ribose) links the DNA damage response and biomineralization KH Müller, R Hayward, R Rajan, M Whitehead, AM Cobb, S Ahmad, ... Cell reports 27 (11), 3124-3138. e13, 2019 | 83 | 2019 |
Rational design of a conformation-specific antibody for the quantification of Aβ oligomers FA Aprile, P Sormanni, M Podpolny, S Chhangur, LM Needham, ... Proceedings of the National Academy of Sciences 117 (24), 13509-13518, 2020 | 80 | 2020 |
Spectrally resolved photodynamics of individual emitters in large-area monolayers of hexagonal boron nitride HL Stern, R Wang, Y Fan, R Mizuta, JC Stewart, LM Needham, ... ACS nano 13 (4), 4538-4547, 2019 | 75 | 2019 |
ThX–a next-generation probe for the early detection of amyloid aggregates LM Needham, J Weber, JA Varela, JWB Fyfe, DT Do, CK Xu, L Tutton, ... Chemical Science 11 (18), 4578-4583, 2020 | 64 | 2020 |
Wild-type sTREM2 blocks Aβ aggregation and neurotoxicity, but the Alzheimer's R47H mutant increases Aβ aggregation A Vilalta, Y Zhou, J Sevalle, JK Griffin, K Satoh, DH Allendorf, S De, ... Journal of Biological Chemistry 296, 2021 | 55 | 2021 |
FRET-enhanced photostability allows improved single-molecule tracking of proteins and protein complexes in live mammalian cells S Basu, LM Needham, D Lando, EJR Taylor, KJ Wohlfahrt, D Shah, ... Nature communications 9 (1), 2520, 2018 | 36 | 2018 |
vLUME: 3D virtual reality for single-molecule localization microscopy A Spark, A Kitching, D Esteban-Ferrer, A Handa, AR Carr, LM Needham, ... Nature methods 17 (11), 1097-1099, 2020 | 35 | 2020 |
Single-molecule fluorescence detection of a tricyclic nucleoside analogue GN Samaan, MK Wyllie, JM Cizmic, LM Needham, D Nobis, K Ngo, ... Chemical science 12 (7), 2623-2628, 2021 | 27 | 2021 |
A comparative photophysical study of structural modifications of thioflavin T-inspired fluorophores LM Needham, J Weber, CM Pearson, DT Do, F Gorka, G Lyu, ... The journal of physical chemistry letters 11 (19), 8406-8416, 2020 | 22 | 2020 |
Bifunctional fluorescent probes for detection of amyloid aggregates and reactive oxygen species LM Needham, J Weber, JWB Fyfe, OM Kabia, DT Do, E Klimont, Y Zhang, ... Royal Society Open Science 5 (2), 171399, 2018 | 21 | 2018 |
POLCAM: instant molecular orientation microscopy for the life sciences E Bruggeman, O Zhang, LM Needham, M Körbel, S Daly, M Cheetham, ... Nature Methods 21 (10), 1873-1883, 2024 | 12 | 2024 |
The pure rotational spectra of the open-shell diatomic molecules PbI and SnI CJ Evans, LME Needham, NR Walker, H Köckert, DP Zaleski, ... The Journal of Chemical Physics 143 (24), 2015 | 12 | 2015 |
Live-cell three-dimensional single-molecule tracking reveals modulation of enhancer dynamics by NuRD S Basu, O Shukron, D Hall, P Parutto, A Ponjavic, D Shah, W Boucher, ... Nature structural & molecular biology 30 (11), 1628-1639, 2023 | 10 | 2023 |
Label-free detection and profiling of individual solution-phase molecules LM Needham, C Saavedra, JK Rasch, D Sole-Barber, BS Schweitzer, ... Nature 629 (8014), 1062-1068, 2024 | 8 | 2024 |
A comparative study of high-contrast fluorescence lifetime probes for imaging amyloid in tissue F Gorka, S Daly, CM Pearson, E Bulovaite, YP Zhang, A Handa, ... The Journal of Physical Chemistry B 125 (50), 13710-13717, 2021 | 7 | 2021 |
Single-molecule visualization of DNA G-quadruplex formation in live cells. Nat. Chem. 12, 832–837 M Di Antonio, A Ponjavic, A Radzevicius, RT Ranasinghe, M Catalano, ... | 7 | 2020 |
Large-scale visualisation of α-synuclein oligomers in Parkinson’s disease brain tissue R Andrews, B Fu, CE Toomey, JC Breiter, J Lachica, R Tian, JS Beckwith, ... bioRxiv, 2024.02. 17.580698, 2024 | 3 | 2024 |
The Origin of Single-Molecule Sensitivity in Label-Free Solution-Phase Optical Microcavity Detection CA Saavedra Salazar, D Sole-Barber, S Wan, JK Rasch, M Reitz, ... ACS Nano, 2025 | | 2025 |
Vortex light field microscopy: 3D spectral single-molecule imaging with a twist B Zhang, S Daly, C Zhu, MO Lenz, LE Weiss, LM Needham, R Peters, ... Optica 11 (11), 1519-1525, 2024 | | 2024 |