Differential inhibition of TRAIL-mediated DR5-DISC formation by decoy receptors 1 and 2 D Mérino, N Lalaoui, A Morizot, P Schneider, E Solary, O Micheau Molecular and cellular biology 26 (19), 7046-7055, 2006 | 410 | 2006 |
Spatial omics and multiplexed imaging to explore cancer biology SM Lewis, ML Asselin-Labat, Q Nguyen, J Berthelet, X Tan, VC Wimmer, ... Nature methods 18 (9), 997-1012, 2021 | 408 | 2021 |
BH3-mimetic drugs: blazing the trail for new cancer medicines D Merino, GL Kelly, G Lessene, AH Wei, AW Roberts, A Strasser Cancer cell 34 (6), 879-891, 2018 | 317 | 2018 |
Targeting BCL-2 with the BH3 mimetic ABT-199 in estrogen receptor-positive breast cancer F Vaillant, D Merino, L Lee, K Breslin, B Pal, ME Ritchie, GK Smyth, ... Cancer cell 24 (1), 120-129, 2013 | 317 | 2013 |
The role of BH3-only protein Bim extends beyond inhibiting Bcl-2–like prosurvival proteins D Mérino, M Giam, PD Hughes, OM Siggs, K Heger, LA O'Reilly, ... Journal of Cell Biology 186 (3), 355-362, 2009 | 235 | 2009 |
Bcl-2, Bcl-xL, and Bcl-w are not equivalent targets of ABT-737 and navitoclax (ABT-263) in lymphoid and leukemic cells D Mérino, SL Khaw, SP Glaser, DJ Anderson, LD Belmont, C Wong, ... Blood, The Journal of the American Society of Hematology 119 (24), 5807-5816, 2012 | 234 | 2012 |
TRAIL in cancer therapy: present and future challenges D Mérino, N Lalaoui, A Morizot, E Solary, O Micheau Expert opinion on therapeutic targets 11 (10), 1299-1314, 2007 | 208 | 2007 |
Synergistic action of the MCL-1 inhibitor S63845 with current therapies in preclinical models of triple-negative and HER2-amplified breast cancer D Merino, JR Whittle, F Vaillant, A Serrano, JN Gong, G Giner, ... Science translational medicine 9 (401), eaam7049, 2017 | 196 | 2017 |
Targeting BCL-2 to enhance vulnerability to therapy in estrogen receptor-positive breast cancer D Merino, SW Lok, JE Visvader, GJ Lindeman Oncogene 35 (15), 1877-1887, 2016 | 177 | 2016 |
Barcoding reveals complex clonal behavior in patient-derived xenografts of metastatic triple negative breast cancer D Merino, TS Weber, A Serrano, F Vaillant, K Liu, B Pal, L Di Stefano, ... Nature communications 10 (1), 766, 2019 | 142 | 2019 |
Neoadjuvant neratinib promotes ferroptosis and inhibits brain metastasis in a novel syngeneic model of spontaneous HER2+ ve breast cancer metastasis A Nagpal, RP Redvers, X Ling, S Ayton, M Fuentes, E Tavancheh, I Diala, ... Breast Cancer Research 21 (1), 1-19, 2019 | 128 | 2019 |
Both leukaemic and normal peripheral B lymphoid cells are highly sensitive to the selective pharmacological inhibition of prosurvival Bcl-2 with ABT-199 SL Khaw, D Merino, MA Anderson, SP Glaser, P Bouillet, AW Roberts, ... Leukemia 28 (6), 1207-1215, 2014 | 111 | 2014 |
Chemotherapy overcomes TRAIL-R4-mediated TRAIL resistance at the DISC level A Morizot, D Mérino, N Lalaoui, G Jacquemin, V Granci, E Iessi, ... Cell Death & Differentiation 18 (4), 700-711, 2011 | 103 | 2011 |
A mitochondrial block and expression of XIAP lead to resistance to TRAIL-induced apoptosis during progression to metastasis of a colon carcinoma O Ndozangue-Touriguine, M Sebbagh, D Merino, O Micheau, J Bertoglio, ... Oncogene 27 (46), 6012-6022, 2008 | 103 | 2008 |
TRAIL-R4 promotes tumor growth and resistance to apoptosis in cervical carcinoma HeLa cells through AKT N Lalaoui, A Morlé, D Mérino, G Jacquemin, E Iessi, A Morizot, S Shirley, ... PloS one 6 (5), e19679, 2011 | 100 | 2011 |
Arsenic trioxide induces apoptosis of human monocytes during macrophagic differentiation through nuclear factor-κB-related survival pathway down-regulation A Lemarie, C Morzadec, D Mérino, O Micheau, O Fardel, L Vernhet Journal of Pharmacology and Experimental Therapeutics 316 (1), 304-314, 2006 | 97 | 2006 |
Dual inhibition of BCL-XL and MCL-1 is required to induce tumour regression in lung squamous cell carcinomas sensitive to FGFR inhibition CE Weeden, C Ah-Cann, AZ Holik, J Pasquet, JM Garnier, D Merino, ... Oncogene 37 (32), 4475-4488, 2018 | 96 | 2018 |
TRAIL induces receptor-interacting protein 1–dependent and caspase-dependent necrosis-like cell death under acidic extracellular conditions O Meurette, A Rébillard, L Huc, G Le Moigne, D Merino, O Micheau, ... Cancer research 67 (1), 218-226, 2007 | 91 | 2007 |
Apoptotic, necrotic, or fused tumor cells: an equivalent source of antigen for dendritic cell loading N Larmonier, D Mérino, A Nicolas, D Cathelin, A Besson, A Bateman, ... Apoptosis 11, 1513-1524, 2006 | 57 | 2006 |
The inhibition of TNF-α anti-tumoral properties by blocking antibodies promotes tumor growth in a rat model N Larmonier, D Cathelin, C Larmonier, A Nicolas, D Merino, ... Experimental cell research 313 (11), 2345-2355, 2007 | 56 | 2007 |