Mutation of OPA1 causes dominant optic atrophy with external ophthalmoplegia, ataxia, deafness and multiple mitochondrial DNA deletions: a novel disorder of … G Hudson, P Amati-Bonneau, EL Blakely, JD Stewart, L He, AM Schaefer, ... Brain 131 (2), 329-337, 2008 | 508 | 2008 |
Multi-system neurological disease is common in patients with OPA1 mutations P Yu-Wai-Man, PG Griffiths, GS Gorman, CM Lourenco, AF Wright, ... Brain 133 (3), 771-786, 2010 | 465 | 2010 |
A comprehensive analysis of human gene expression profiles identifies stromal immunoglobulin κ C as a compatible prognostic marker in human solid tumors M Schmidt, B Hellwig, S Hammad, A Othman, M Lohr, Z Chen, D Boehm, ... Clinical cancer research 18 (9), 2695-2703, 2012 | 271 | 2012 |
Polymerase γ Gene POLG determines the risk of sodium valproate‐induced liver toxicity JD Stewart, R Horvath, E Baruffini, I Ferrero, S Bulst, PB Watkins, ... Hepatology 52 (5), 1791-1796, 2010 | 258 | 2010 |
Choline-releasing glycerophosphodiesterase EDI3 drives tumor cell migration and metastasis JD Stewart, R Marchan, MS Lesjak, J Lambert, R Hergenroeder, JK Ellis, ... Proceedings of the National Academy of Sciences 109 (21), 8155-8160, 2012 | 136 | 2012 |
Microarrays for the scalable production of metabolically relevant tumour spheroids: a tool for modulating chemosensitivity traits H Hardelauf, JP Frimat, JD Stewart, W Schormann, YY Chiang, P Lampen, ... Lab on a Chip 11 (3), 419-428, 2011 | 118 | 2011 |
The clinical, histochemical, and molecular spectrum of PEO1 (Twinkle)-linked adPEO C Fratter, GS Gorman, JD Stewart, M Buddles, C Smith, J Evans, A Seller, ... Neurology 74 (20), 1619-1626, 2010 | 103 | 2010 |
Interferon-inducible guanylate binding protein (GBP2) is associated with better prognosis in breast cancer and indicates an efficient T cell response P Godoy, C Cadenas, B Hellwig, R Marchan, J Stewart, R Reif, M Lohr, ... Breast Cancer 21, 491-499, 2014 | 101 | 2014 |
Glycerol-3-phosphate acyltransferase 1 promotes tumor cell migration and poor survival in ovarian carcinoma R Marchan, B Büttner, J Lambert, K Edlund, I Glaeser, M Blaszkewicz, ... Cancer research 77 (17), 4589-4601, 2017 | 70 | 2017 |
OPA1 increases the risk of normal but not high tension glaucoma P Yu-Wai-Man, JD Stewart, G Hudson, RM Andrews, PG Griffiths, ... Journal of medical genetics 47 (2), 120-125, 2010 | 65 | 2010 |
In vitro supplementation with dAMP/dGMP leads to partial restoration of mtDNA levels in mitochondrial depletion syndromes S Bulst, A Abicht, E Holinski-Feder, S Müller-Ziermann, U Koehler, ... Human molecular genetics 18 (9), 1590-1599, 2009 | 62 | 2009 |
Dexamethasone-dependent versus -independent markers of epithelial to mesenchymal transition in primary hepatocytes P Godoy, S Lakkapamu, M Schug, A Bauer, JD Stewart, E Bedawi, ... Walter de Gruyter 391 (1), 73-83, 2010 | 60 | 2010 |
Novel POLG1 mutations associated with neuromuscular and liver phenotypes in adults and children JD Stewart, S Tennant, H Powell, A Pyle, EL Blakely, L He, G Hudson, ... Journal of medical genetics 46 (3), 209-214, 2009 | 60 | 2009 |
Clonally expanded mitochondrial DNA mutations in epileptic individuals with mutated DNA polymerase γ G Zsurka, M Baron, JD Stewart, C Kornblum, M Bös, R Sassen, RW Taylor, ... Journal of Neuropathology & Experimental Neurology 67 (9), 857-866, 2008 | 53 | 2008 |
POLG1 mutations manifesting as autosomal recessive axonal Charcot-Marie-Tooth disease T Harrower, JD Stewart, G Hudson, H Houlden, G Warner, DG O’Donovan, ... Archives of neurology 65 (1), 133-136, 2008 | 53 | 2008 |
POLG mutations cause decreased mitochondrial DNA repopulation rates following induced depletion in human fibroblasts JD Stewart, S Schoeler, KS Sitarz, R Horvath, K Hallmann, A Pyle, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1812 (3), 321-325, 2011 | 52 | 2011 |
LIPG‐promoted lipid storage mediates adaptation to oxidative stress in breast cancer C Cadenas, S Vosbeck, K Edlund, K Grgas, K Madjar, B Hellwig, A Adawy, ... International journal of cancer 145 (4), 901-915, 2019 | 50 | 2019 |
MFN2 mutations cause compensatory mitochondrial DNA proliferation KS Sitarz, P Yu-Wai-Man, A Pyle, JD Stewart, B Rautenstrauss, P Seeman, ... Brain 135 (8), e219-e219, 2012 | 48 | 2012 |
Late-onset ptosis and myopathy in a patient with a heterozygous insertion in POLG2 MC Walter, B Czermin, S Muller-Ziermann, S Bulst, JD Stewart, G Hudson, ... Journal of neurology 257, 1517-1523, 2010 | 47 | 2010 |
Immunoglobulin kappa C predicts overall survival in node-negative breast cancer Z Chen, A Gerhold-Ay, S Gebhard, D Boehm, C Solbach, A Lebrecht, ... Public Library of Science 7 (9), e44741, 2012 | 45 | 2012 |