| Caspase substrates and inhibitors M Poręba, A Stróżyk, GS Salvesen, M Drąg Cold Spring Harbor perspectives in biology 5 (8), a008680, 2013 | 278* | 2013 |
| Design of ultrasensitive probes for human neutrophil elastase through hybrid combinatorial substrate library profiling P Kasperkiewicz, M Poreba, SJ Snipas, H Parker, CC Winterbourn, ... Proceedings of the National Academy of Sciences 111 (7), 2518-2523, 2014 | 173 | 2014 |
| Probing the S1 specificity pocket of the aminopeptidases that generate antigenic peptides E Zervoudi, A Papakyriakou, D Georgiadou, I Evnouchidou, A Gajda, ... Biochemical Journal 435 (2), 411-420, 2011 | 122 | 2011 |
| Protease‐activated prodrugs: strategies, challenges, and future directions M Poreba The FEBS journal 287 (10), 1936-1969, 2020 | 117 | 2020 |
| Mechanism and specificity of the human paracaspase MALT1 J Hachmann, SJ Snipas, BJ van Raam, EM Cancino, EJ Houlihan, ... Biochemical Journal 443 (1), 287-295, 2012 | 109 | 2012 |
| Extensive peptide and natural protein substrate screens reveal that mouse caspase-11 has much narrower substrate specificity than caspase-1 MLG Ramirez, M Poreba, SJ Snipas, K Groborz, M Drag, GS Salvesen Journal of Biological Chemistry 293 (18), 7058-7067, 2018 | 98 | 2018 |
| Synthesis of a HyCoSuL peptide substrate library to dissect protease substrate specificity M Poreba, GS Salvesen, M Drag Nature protocols 12 (10), 2189-2214, 2017 | 97 | 2017 |
| Small molecule active site directed tools for studying human caspases M Poreba, A Szalek, P Kasperkiewicz, W Rut, GS Salvesen, M Drag Chemical reviews 115 (22), 12546-12629, 2015 | 90 | 2015 |
| Fingerprinting the substrate specificity of M1 and M17 aminopeptidases of human malaria, Plasmodium falciparum M Poreba, S McGowan, TS Skinner-Adams, KR Trenholme, DL Gardiner, ... PLoS One 7 (2), e31938, 2012 | 89 | 2012 |
| Unnatural amino acids increase sensitivity and provide for the design of highly selective caspase substrates M Poreba, P Kasperkiewicz, SJ Snipas, D Fasci, GS Salvesen, M Drag Cell Death & Differentiation 21 (9), 1482-1492, 2014 | 86 | 2014 |
| Structural and functional insights into caseinolytic proteases reveal an unprecedented regulation principle of their catalytic triad E Zeiler, A List, F Alte, M Gersch, R Wachtel, M Poreba, M Drag, M Groll, ... Proceedings of the National Academy of Sciences 110 (28), 11302-11307, 2013 | 77 | 2013 |
| Selective imaging of cathepsin L in breast cancer by fluorescent activity-based probes M Poreba, W Rut, M Vizovisek, K Groborz, P Kasperkiewicz, D Finlay, ... Chemical Science 9 (8), 2113-2129, 2018 | 74 | 2018 |
| Highly sensitive and adaptable fluorescence-quenched pair discloses the substrate specificity profiles in diverse protease families M Poreba, A Szalek, W Rut, P Kasperkiewicz, I Rutkowska-Wlodarczyk, ... Scientific reports 7 (1), 1-13, 2017 | 74 | 2017 |
| Fluorescent probes towards selective cathepsin B detection and visualization in cancer cells and patient samples M Poreba, K Groborz, M Vizovisek, M Maruggi, D Turk, B Turk, G Powis, ... Chemical science 10 (36), 8461-8477, 2019 | 68 | 2019 |
| Current strategies for probing substrate specificity of proteases M Poreba, M Drag Current medicinal chemistry 17 (33), 3968-3995, 2010 | 64 | 2010 |
| Extended substrate specificity and first potent irreversible inhibitor/activity-based probe design for Zika virus NS2B-NS3 protease W Rut, L Zhang, P Kasperkiewicz, M Poreba, R Hilgenfeld, M Drąg Antiviral research 139, 88-94, 2017 | 62 | 2017 |
| Design of a selective substrate and activity based probe for human neutrophil serine protease 4 P Kasperkiewicz, M Poreba, SJ Snipas, SJ Lin, D Kirchhofer, ... PLoS One 10 (7), e0132818, 2015 | 62 | 2015 |
| Counter selection substrate library strategy for developing specific protease substrates and probes M Poreba, R Solberg, W Rut, NN Lunde, P Kasperkiewicz, SJ Snipas, ... Cell chemical biology 23 (8), 1023-1035, 2016 | 61 | 2016 |
| Emerging challenges in the design of selective substrates, inhibitors and activity‐based probes for indistinguishable proteases P Kasperkiewicz, M Poreba, K Groborz, M Drag The FEBS journal 284 (10), 1518-1539, 2017 | 60 | 2017 |
| Anticancer properties of ester derivatives of betulin in human metastatic melanoma cells (Me-45) M Drąg-Zalesińska, M Drąg, M Poręba, S Borska, J Kulbacka, J Saczko Cancer Cell International 17, 1-7, 2017 | 58 | 2017 |
Marcin DragProfessor, Department of Chemical Biology and Bioimaging, Wroclaw University of TechnologyEmail verificata su pwr.edu.pl