| Towards novel anti-cancer strategies based on cystatin function D Keppler Cancer letters 235 (2), 159-176, 2006 | 214 | 2006 |
| Exocytosis of active cathepsin B: enzyme activity at pH 7.0, inhibition and molecular mass BE Linebaugh, M Sameni, NA Day, BF Sloane, D Keppler European journal of biochemistry 264 (1), 100-109, 1999 | 189 | 1999 |
| Tumor progression and angiogenesis: cathepsin B &Co. D Keppler, M Sameni, K Moin, BF Sloane, T Mikkelsen, CA Diglio Biochemistry and cell biology 74 (6), 799-810, 1996 | 166 | 1996 |
| Cystatin M: a novel candidate tumor Suppressor gene for breast cancer J Zhang, R Shridhar, Q Dai, J Song, SC Barlow, L Yin, BF Sloane, ... Cancer research 64 (19), 6957-6964, 2004 | 124 | 2004 |
| Cystatin M suppresses the malignant phenotype of human MDA-MB-435S cells R Shridhar, J Zhang, J Song, BA Booth, CG Kevil, G Sotiropoulou, ... Oncogene 23 (12), 2206-2215, 2004 | 116 | 2004 |
| Cathepsin B: multiple enzyme forms from a single gene and their relation to cancer D Keppler, BF Sloane Enzyme and Protein 49 (1-3), 94-105, 1996 | 110 | 1996 |
| Cystatin C and cathepsin B in human colon carcinoma: expression by cell lines and matrix degradation O Coriicchiato, JF Cajot, M Abrahamson, SJ Chan, D Keppler, B Sordat International journal of cancer 52 (4), 645-652, 1992 | 106 | 1992 |
| Analysis of a truncated form of cathepsin H in human prostate tumor cells A Waghray, D Keppler, BF Sloane, L Schuger, YQ Chen Journal of Biological Chemistry 277 (13), 11533-11538, 2002 | 90 | 2002 |
| Immunohistochemical and biochemical study of a cathepsin B-like proteinase in human colonic cancers D Keppler, MC Fondaneche, V Dalet-Fumeron, M Pagano, P Burtin Cancer research 48 (23), 6855-6862, 1988 | 77 | 1988 |
| Fluorescent microplate assay for cancer cell‐associated cathepsin B KI Hulkower, CC Butler, BE Linebaugh, JL Klaus, D Keppler, VL Giranda, ... European Journal of Biochemistry 267 (13), 4165-4170, 2000 | 75 | 2000 |
| Latency of cathepsin B secreted by human colon carcinoma cells is not linked to secretion of cystacin C and is relieved by neutrophil elastase D Keppler, P Waridel, M Abrahamson, D Bachmann, J Berdoz, B Sordat Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1226 (2), 117-125, 1994 | 63 | 1994 |
| Methylation-dependent silencing of CST6 in primary human breast tumors and metastatic lesions AG Rivenbark, CA Livasy, CE Boyd, D Keppler, WB Coleman Experimental and molecular pathology 83 (2), 188-197, 2007 | 57 | 2007 |
| Intracellular accumulation of the amyloidogenic L68Q variant of human cystatin C in NIH/3T3 cells. M Bjarnadottir, BS Wulff, M Sameni, BF Sloane, D Keppler, A Grubb, ... Molecular Pathology 51 (6), 317, 1998 | 48 | 1998 |
| Secretion of cathepsin B and tumour invasion D Keppler, M Abrahamson, B Sordat Biochemical Society Transactions 22 (1), 43-49, 1994 | 46 | 1994 |
| Inactivation of the cystatin E/M tumor suppressor gene in cervical cancer MS Veena, G Lee, D Keppler, MS Mendonca, JL Redpath, EJ Stanbridge, ... Genes, Chromosomes and Cancer 47 (9), 740-754, 2008 | 44 | 2008 |
| The candidate tumor suppressor CST6 alters the gene expression profile of human breast carcinoma cells: down-regulation of the potent mitogenic, motogenic, and angiogenic … J Song, C Jie, P Polk, R Shridhar, T Clair, J Zhang, L Yin, D Keppler Biochemical and biophysical research communications 340 (1), 175-182, 2006 | 41 | 2006 |
| Cathespin H is an Fgf10 target involved in Bmp4 degradation during lung branching morphogenesis J Lü, J Qian, D Keppler, WV Cardoso Journal of Biological Chemistry 282 (30), 22176-22184, 2007 | 35 | 2007 |
| Increased expression of mature cathepsin B in aging rat liver D Keppler, R Walter, C Pérez, F Sierra Cell and tissue research 302, 181-188, 2000 | 34 | 2000 |
| Human Colon Carcinoma Cells Synthesize and Secrete α1-Proteinase Inhibitor D Keppler, M Markert, B Carnal, J Berdoz, J Bamat, B Sordat Walter de Gruyter, Berlin/New York 377 (5), 301-312, 1996 | 29 | 1996 |
| Defined genetic events associated with the spontaneous in vitro transformation of ElA/Ras-expressing human IMR90 fibroblasts DX Mason, D Keppler, J Zhang, TJ Jackson, YR Seger, S Matsui, F Abreo, ... Carcinogenesis 27 (2), 350-359, 2006 | 23 | 2006 |
