Regulation of hepatic fasting response by PPARγ coactivator-1α (PGC-1): requirement for hepatocyte nuclear factor 4α in gluconeogenesis J Rhee, Y Inoue, JC Yoon, P Puigserver, M Fan, FJ Gonzalez, ... Proceedings of the national academy of sciences 100 (7), 4012-4017, 2003 | 723 | 2003 |
The orphan nuclear receptor HNF4α determines PXR-and CAR-mediated xenobiotic induction of CYP3A4 RG Tirona, W Lee, BF Leake, LB Lan, CB Cline, V Lamba, F Parviz, ... Nature medicine 9 (2), 220-224, 2003 | 559 | 2003 |
Prevention of acute liver failure in rats with reversibly immortalized human hepatocytes N Kobayashi, T Fujiwara, KA Westerman, Y Inoue, M Sakaguchi, ... Science 287 (5456), 1258-1262, 2000 | 496 | 2000 |
Hepatocyte growth factor induces differentiation of adult rat bone marrow cells into a hepatocyte lineage in vitro SH Oh, M Miyazaki, H Kouchi, Y Inoue, M Sakaguchi, T Tsuji, N Shima, ... Biochemical and Biophysical Research Communications 279 (2), 500-504, 2000 | 490 | 2000 |
Glucocorticoid signaling synchronizes the liver circadian transcriptome AB Reddy, ES Maywood, NA Karp, VM King, Y Inoue, FJ Gonzalez, ... Hepatology 45 (6), 1478-1488, 2007 | 325 | 2007 |
C/EBPα regulates hepatic transcription of hepcidin, an antimicrobial peptide and regulator of iron metabolism: cross-talk between C/EBP pathway and iron metabolism B Courselaud, C Pigeon, Y Inoue, J Inoue, FJ Gonzalez, P Leroyer, ... Journal of Biological Chemistry 277 (43), 41163-41170, 2002 | 323 | 2002 |
Farnesoid X receptor agonists suppress hepatic apolipoprotein CIII expression T Claudel, Y Inoue, O Barbier, D Duran-Sandoval, V Kosykh, J Fruchart, ... Gastroenterology 125 (2), 544-555, 2003 | 322 | 2003 |
A REIC gene shows down-regulation in human immortalized cells and human tumor-derived cell lines T Tsuji, M Miyazaki, M Sakaguchi, Y Inoue, M Namba Biochemical and biophysical research communications 268 (1), 20-24, 2000 | 229 | 2000 |
Hepatocyte nuclear factor-4α is essential for glucose-stimulated insulin secretion by pancreatic β-cells A Miura, K Yamagata, M Kakei, H Hatakeyama, N Takahashi, K Fukui, ... Journal of Biological Chemistry 281 (8), 5246-5257, 2006 | 199 | 2006 |
Hepatocyte nuclear factor 4α in the intestinal epithelial cells protects against inflammatory bowel disease SH Ahn, YM Shah, J Inoue, K Morimura, I Kim, SH Yim, G Lambert, ... Inflammatory bowel diseases 14 (7), 908-920, 2008 | 194 | 2008 |
Role of the hepatocyte nuclear factor 4α in control of the pregnane X receptor during fetal liver development A Kamiya, Y Inoue, FJ Gonzalez Hepatology 37 (6), 1375-1384, 2003 | 179 | 2003 |
Regulation of bile acid biosynthesis by hepatocyte nuclear factor 4α Y Inoue, AM Yu, SH Yim, X Ma, KW Krausz, J Inoue, CC Xiang, ... Journal of lipid research 47 (1), 215-227, 2006 | 165 | 2006 |
Relationship between contact inhibition and intranuclear S100C of normal human fibroblasts M Sakaguchi, M Miyazaki, Y Inoue, T Tsuji, H Kouchi, T Tanaka, ... The Journal of cell biology 149 (6), 1193-1206, 2000 | 141 | 2000 |
Defective ureagenesis in mice carrying a liver-specific disruption of hepatocyte nuclear factor 4α (HNF4α): HNF4α regulates ornithine transcarbamylase in vivo Y Inoue, GP Hayhurst, J Inoue, M Mori, FJ Gonzalez Journal of Biological Chemistry 277 (28), 25257-25265, 2002 | 136 | 2002 |
TRANSPLANTATION OF HIGHLY DIFFERENTIATED IMMORTALIZED HUMAN HEPATOCYTES TO TREAT ACUTE LIVER FAILURE 1 N Kobayashi, M Miyazaki, K Fukaya, Y Inoue, M Sakaguchi, T Uemura, ... Transplantation 69 (2), 202, 2000 | 127 | 2000 |
Hepatocyte nuclear factor 4α is a central regulator of bile acid conjugation Y Inoue, AM Yu, J Inoue, FJ Gonzalez Journal of Biological Chemistry 279 (4), 2480-2489, 2004 | 121 | 2004 |
Enhanced expression of cyclin E and cyclin A in human hepatocellular carcinomas. R Ohashi, C Gao, M Miyazaki, K Hamazaki, T Tsuji, Y Inoue, T Uemura, ... Anticancer research 21 (1B), 657-662, 2001 | 98 | 2001 |
Hepatic CCAAT/enhancer binding protein α mediates induction of lipogenesis and regulation of glucose homeostasis in leptin-deficient mice K Matsusue, O Gavrilova, G Lambert, HB Brewer Jr, JM Ward, Y Inoue, ... Molecular endocrinology 18 (11), 2751-2764, 2004 | 92 | 2004 |
Disruption of hepatic C/EBPα results in impaired glucose tolerance and age-dependent hepatosteatosis Y Inoue, J Inoue, G Lambert, SH Yim, FJ Gonzalez Journal of Biological Chemistry 279 (43), 44740-44748, 2004 | 90 | 2004 |
An HNF4α–microRNA-194/192 signaling axis maintains hepatic cell function A Morimoto, M Kannari, Y Tsuchida, S Sasaki, C Saito, T Matsuta, ... Journal of Biological Chemistry 292 (25), 10574-10585, 2017 | 85 | 2017 |