| Biofilm in group A streptococcal necrotizing soft tissue infections N Siemens, B Chakrakodi, SM Shambat, M Morgan, H Bergsten, ... JCI insight 1 (10), 2016 | 79 | 2016 |
| Streptococcus pyogenes M49 plasminogen/plasmin binding facilitates keratinocyte invasion via integrin-integrin-linked kinase (ILK) pathways and protects from macrophage killing N Siemens, N Patenge, J Otto, T Fiedler, B Kreikemeyer Journal of Biological Chemistry 286 (24), 21612-21622, 2011 | 72 | 2011 |
| Modelling staphylococcal pneumonia in a human 3D lung tissue model system delineates toxin-mediated pathology S Mairpady Shambat, P Chen, AT Nguyen Hoang, H Bergsten, ... Disease models & mechanisms 8 (11), 1413-1425, 2015 | 63 | 2015 |
| Differential neutrophil responses to bacterial stimuli: Streptococcal strains are potent inducers of heparin-binding protein and resistin-release J Snäll, A Linnér, J Uhlmann, N Siemens, H Ibold, M Janos, A Linder, ... Scientific reports 6 (1), 21288, 2016 | 61 | 2016 |
| The role of streptococcal and staphylococcal exotoxins and proteases in human necrotizing soft tissue infections P Shumba, S Mairpady Shambat, N Siemens Toxins 11 (6), 332, 2019 | 40 | 2019 |
| Port d’Entrée for respiratory infections–Does the influenza a virus pave the way for bacteria? N Siemens, S Oehmcke-Hecht, TC Mettenleiter, B Kreikemeyer, ... Frontiers in microbiology 8, 2602, 2017 | 40 | 2017 |
| Hydrogen peroxide is crucial for NLRP3 inflammasome-mediated IL-1β production and cell death in pneumococcal infections of bronchial epithelial cells S Surabhi, LH Jachmann, P Shumba, G Burchhardt, S Hammerschmidt, ... Journal of Innate Immunity 14 (3), 192-206, 2022 | 36 | 2022 |
| Genetic architecture of group A streptococcal necrotizing soft tissue infections in the mouse K Chella Krishnan, S Mukundan, J Alagarsamy, J Hur, S Nookala, ... PLoS pathogens 12 (7), e1005732, 2016 | 36 | 2016 |
| Increased cytotoxicity and streptolysin O activity in group G streptococcal strains causing invasive tissue infections N Siemens, BR Kittang, B Chakrakodi, O Oppegaard, L Johansson, ... Scientific Reports 5 (1), 16945, 2015 | 36 | 2015 |
| Effects of the ERES pathogenicity region regulator Ralp3 on Streptococcus pyogenes serotype M49 virulence factor expression N Siemens, T Fiedler, J Normann, J Klein, R Münch, N Patenge, ... Journal of bacteriology 194 (14), 3618-3626, 2012 | 36 | 2012 |
| A point mutation in AgrC determines cytotoxic or colonizing properties associated with phenotypic variants of ST22 MRSA strains S Mairpady Shambat, N Siemens, IR Monk, DB Mohan, S Mukundan, ... Scientific reports 6 (1), 31360, 2016 | 35 | 2016 |
| Characterization of Three Lactic Acid Bacteria and Their Isogenic ldh Deletion Mutants Shows Optimization for Y ATP (Cell Mass Produced per Mole of ATP) at … T Fiedler, M Bekker, M Jonsson, I Mehmeti, A Pritzschke, N Siemens, ... Applied and environmental microbiology 77 (2), 612-617, 2011 | 35 | 2011 |
| The extracellular protein factor Epf from Streptococcus pyogenes is a cell surface adhesin that binds to cells through an N-terminal domain containing a carbohydrate-binding module C Linke, N Siemens, S Oehmcke, M Radjainia, RHP Law, JC Whisstock, ... Journal of Biological Chemistry 287 (45), 38178-38189, 2012 | 34 | 2012 |
| LL-37 triggers formation of Streptococcus pyogenes extracellular vesicle-like structures with immune stimulatory properties J Uhlmann, M Rohde, N Siemens, B Kreikemeyer, P Bergman, ... Journal of innate immunity 8 (3), 243-257, 2016 | 33 | 2016 |
| The role of NLRP3 inflammasome in pneumococcal infections S Surabhi, F Cuypers, S Hammerschmidt, N Siemens Frontiers in Immunology 11, 614801, 2020 | 28 | 2020 |
| Prothrombotic and proinflammatory activities of the β-hemolytic group B streptococcal pigment N Siemens, S Oehmcke-Hecht, J Hoßmann, SB Skorka, RHT Nijhuis, ... Journal of innate immunity 12 (4), 291-303, 2020 | 20 | 2020 |
| Streptococcus pyogenes (“Group A Streptococcus”), a Highly Adapted Human Pathogen—Potential Implications of Its Virulence Regulation for Epidemiology and … N Siemens, R Lütticken Pathogens 10 (6), 776, 2021 | 19 | 2021 |
| Innate immune responses at the asymptomatic stage of influenza A viral infections of Streptococcus pneumoniae colonized and non-colonized mice F Cuypers, A Schäfer, SB Skorka, S Surabhi, LA Tölken, AD Paulikat, ... Scientific reports 11 (1), 20609, 2021 | 18 | 2021 |
| Glycoconjugated Phthalocyanines as photosensitizers for PDT–Overcoming aggregation in solution F Bächle, N Siemens, T Ziegler European Journal of Organic Chemistry 2019 (42), 7089-7116, 2019 | 17 | 2019 |
| Phosphoglycerate kinase—a novel streptococcal factor involved in neutrophil activation and degranulation J Uhlmann, N Siemens, Y Kai-Larsen, T Fiedler, P Bergman, L Johansson, ... The Journal of Infectious Diseases 214 (12), 1876-1883, 2016 | 16 | 2016 |
