Emerging treatment mechanisms for depression: focus on glutamate and synaptic plasticity DM Gerhard, ES Wohleb, RS Duman Drug discovery today 21 (3), 454-464, 2016 | 335 | 2016 |
GABA interneurons are the cellular trigger for ketamine’s rapid antidepressant actions DM Gerhard, S Pothula, RJ Liu, M Wu, XY Li, MJ Girgenti, SR Taylor, ... The Journal of clinical investigation 130 (3), 1336-1349, 2020 | 287 | 2020 |
Ketamine disinhibits dendrites and enhances calcium signals in prefrontal dendritic spines F Ali, DM Gerhard, K Sweasy, S Pothula, C Pittenger, RS Duman, ... Nature Communications 11 (1), 72, 2020 | 185 | 2020 |
Molecular and cellular mechanisms of rapid-acting antidepressants ketamine and scopolamine E S Wohleb, D Gerhard, A Thomas, R S Duman Current neuropharmacology 15 (1), 11-20, 2017 | 156 | 2017 |
GABA interneurons mediate the rapid antidepressant-like effects of scopolamine. ES Wohleb, M Wu, DM Gerhard, SR Taylor, MR Picciotto, M Alreja, ... The Journal of clinical investigation 126 (7), 2482-2494, 2016 | 155 | 2016 |
Experimenters’ sex modulates mouse behaviors and neural responses to ketamine via corticotropin releasing factor P Georgiou, P Zanos, TCM Mou, X An, DM Gerhard, DI Dryanovski, ... Nature neuroscience 25 (9), 1191-1200, 2022 | 105 | 2022 |
Role of neuronal VEGF signaling in the prefrontal cortex in the rapid antidepressant effects of ketamine S Deyama, E Bang, ES Wohleb, XY Li, T Kato, DM Gerhard, S Dutheil, ... American Journal of Psychiatry 176 (5), 388-400, 2019 | 103 | 2019 |
Cell-type specific modulation of NMDA receptors triggers antidepressant actions S Pothula, T Kato, RJ Liu, M Wu, D Gerhard, R Shinohara, AN Sliby, ... Molecular Psychiatry 26 (9), 5097-5111, 2021 | 71 | 2021 |
Cacna1c in the prefrontal cortex regulates depression-related behaviors via REDD1 ZD Kabir, AS Lee, CE Burgdorf, DK Fischer, AM Rajadhyaksha, E Mok, ... Neuropsychopharmacology 42 (10), 2032-2042, 2017 | 67 | 2017 |
Rapid-acting antidepressants: mechanistic insights and future directions DM Gerhard, RS Duman Current behavioral neuroscience reports 5, 36-47, 2018 | 64 | 2018 |
Predicting barriers to treatment for depression in a US national sample: a cross-sectional, proof-of-concept study AM Chekroud, D Foster, AB Zheutlin, DM Gerhard, B Roy, N Koutsouleris, ... Psychiatric services 69 (8), 927-934, 2018 | 55 | 2018 |
A diet enriched with curcumin impairs newly acquired and reactivated fear memories MS Monsey, DM Gerhard, LM Boyle, MA Briones, M Seligsohn, ... Neuropsychopharmacology 40 (5), 1278-1288, 2015 | 48 | 2015 |
Maintenance of dominance status is necessary for resistance to social defeat stress in Syrian hamsters KE Morrison, LR Bader, CT Clinard, DM Gerhard, SE Gross, MA Cooper Behavioural brain research 270, 277-286, 2014 | 46 | 2014 |
An adolescent sensitive period for threat responding: impacts of stress and sex DM Gerhard, HC Meyer, FS Lee Biological psychiatry 89 (7), 651-658, 2021 | 41 | 2021 |
Inhibitory regulation of calcium transients in prefrontal dendritic spines is compromised by a nonsense Shank3 mutation F Ali, LX Shao, DM Gerhard, K Sweasy, S Pothula, C Pittenger, ... Molecular psychiatry 26 (6), 1945-1966, 2021 | 22 | 2021 |
Pre-adolescent stress disrupts adult, but not adolescent, safety learning HC Meyer, DM Gerhard, PA Amelio, FS Lee Behavioural Brain Research 400, 113005, 2021 | 22 | 2021 |
The added value of crosstalk between developmental circuit neuroscience and clinical practice to inform the treatment of adolescent anxiety HC Meyer, A Fields, A Vannucci, DM Gerhard, PA Bloom, C Heleniak, ... Biological Psychiatry Global Open Science 3 (2), 169-178, 2023 | 15 | 2023 |
Extinction trial spacing across days differentially impacts fear regulation in adult and adolescent male mice DM Gerhard, HC Meyer Neurobiology of learning and memory 186, 107543, 2021 | 11 | 2021 |
Obesity. Introduction. MS Monsey, DM Gerhard The Yale Journal of Biology and Medicine 87 (2), 97-98, 2014 | 11 | 2014 |
Synaptic plasticity via receptor tyrosine kinase/G-protein-coupled receptor crosstalk C Lao-Peregrin, G Xiang, J Kim, I Srivastava, AB Fall, DM Gerhard, ... Cell Reports 43 (1), 2024 | 7 | 2024 |