Cathepsin L proteinase secreted by Fasciola hepatica in vitro prevents antibody-mediated eosinophil attachment to newly excysted juveniles C Carmona, AJ Dowd, AM Smith, JP Dalton Molecular and biochemical parasitology 62 (1), 9-17, 1993 | 269 | 1993 |
Purification of a cathepsin L-like proteinase secreted by adult Fasciola hepatica AM Smith, AJ Dowd, S McGonigle, PS Keegan, G Brennan, A Trudgett, ... Molecular and biochemical parasitology 62 (1), 1-8, 1993 | 213 | 1993 |
Correlation of specific antibody titre and avidity with protection in cattle immunized against Fasciola hepatica G Mulcahy, F O'Connor, S McGonigle, A Dowd, DG Clery, SJ Andrews, ... Vaccine 16 (9-10), 932-939, 1998 | 183 | 1998 |
Proteinases secreted by Fasciola hepatica degrade extracelullar matrix and basement membrane components P Berasaín, F Goñi, S McGonigle, A Dowd, JP Dalton, B Frangione, ... The Journal of parasitology, 1-5, 1997 | 182 | 1997 |
Fasciola hepatica: a secreted cathepsin L-like proteinase cleaves host immunoglobulin AM Smith, AJ Dowd, M Heffernan, CD Robertson, JP Dalton International journal for parasitology 23 (8), 977-983, 1993 | 149 | 1993 |
Purification and characterisation of a second cathepsin L proteinase secreted by the parasitic trematode Fasciola hepatica AJ Dowd, AM Smith, S McGONIGLE, JP Dalton European Journal of Biochemistry 223 (1), 91-98, 1994 | 144 | 1994 |
Metabolic and Target-Site Mechanisms Combine to Confer Strong DDT Resistance in Anopheles gambiae SN Mitchell, DJ Rigden, AJ Dowd, F Lu, CS Wilding, D Weetman, ... PloS one 9 (3), e92662, 2014 | 140 | 2014 |
Immune responses of cattle to experimental anti-Fasciola hepaticavaccines G Mulcahy, F O’connor, D Clery, SF Hogan, AJ Dowd, SJ Andrews, ... Research in veterinary science 67 (1), 27-33, 1999 | 126 | 1999 |
Immunodiagnosis of human fascioliasis using recombinant Fasciola hepatica cathepsin L1 cysteine proteinase. SM O'Neill, M Parkinson, AJ Dowd, W Strauss, R Angles, JP Dalton The American journal of tropical medicine and hygiene 60 (5), 749-751, 1999 | 124 | 1999 |
Recombinant Expression and Localization ofSchistosoma mansoni Cathepsin L1 Support Its Role in the Degradation of Host Hemoglobin CP Brady, AJ Dowd, PJ Brindley, T Ryan, SR Day, JP Dalton Infection and Immunity 67 (1), 368-374, 1999 | 120 | 1999 |
Proteomic analysis of isolated membrane fractions from superinvasive cancer cells P Dowling, P Meleady, A Dowd, M Henry, S Glynn, M Clynes Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1774 (1), 93-101, 2007 | 109 | 2007 |
Proteomic screening of glucose‐responsive and glucose non‐responsive MIN‐6 beta cells reveals differential expression of proteins involved in protein folding, secretion and … P Dowling, L O'Driscoll, F O'Sullivan, A Dowd, M Henry, PB Jeppesen, ... Proteomics 6 (24), 6578-6587, 2006 | 77 | 2006 |
Functional Expression of Fasciola Hepatica Cathepsin L1 in Saccharomyces Cerevisiae L Roche, AJ Dowd, J Tort, S McGonigle, A McSweeney, GP Curley, ... European Journal of Biochemistry 245 (2), 373-380, 1997 | 76 | 1997 |
Isolation of a cDNA encoding Fasciola hepatica cathepsin L2 and functional expression in Saccharomyces cerevisiae AJ Dowd, J Tort, L Roche, T Ryan, JP Dalton Molecular and biochemical parasitology 88 (1-2), 163-174, 1997 | 71 | 1997 |
Fasciola Hepatica Cathepsin L Proteinase Cleaves Fibrinogen and Produces a Novel Type of Fibrin Clot AJ Dowd, S McGonigle, JP Dalton European journal of biochemistry 232 (1), 241-246, 1995 | 67 | 1995 |
Secretion of cysteine proteinase activity by the zoonotic hookworm Ancylostoma caninum. AJ Dowd, JP Dalton, AC Loukas, P Prociv, PJ Brindley The American journal of tropical medicine and hygiene 51 (3), 341-347, 1994 | 49 | 1994 |
Neutralization of the activity of a Fasciola hepatica cathepsin L proteinase by anti‐cathepsin L antibodies AM SMITH, C CARMONA, AJ DOWD, S McGONIGLE, D ACOSTA, ... Parasite immunology 16 (6), 325-328, 1994 | 43 | 1994 |
Schistosoma mansoni: differential expression of cathepsins L1 and L2 suggests discrete biological functions for each enzyme CP Brady, PJ Brindley, AJ Dowd, JP Dalton Experimental parasitology 94 (2), 75-83, 2000 | 42 | 2000 |
Molecular modeling and substrate specificity of discrete cruzipain-like and cathepsin L-like cysteine proteinases of the human blood fluke Schistosoma mansoni CP Brady, RI Brinkworth, JP Dalton, AJ Dowd, CK Verity, PJ Brindley Archives of Biochemistry and Biophysics 380 (1), 46-55, 2000 | 41 | 2000 |
A dipeptidylpeptidase secreted by Fasciola hepatica C Carmona, S McGonigle, AJ Dowd, AM Smith, S Coughlan, E McGowran, ... Parasitology 109 (1), 113-118, 1994 | 40 | 1994 |