MHCII is required for α-synuclein-induced activation of microglia, CD4 T cell proliferation, and dopaminergic neurodegeneration AS Harms, S Cao, AL Rowse, AD Thome, X Li, LR Mangieri, RQ Cron, ... Journal of Neuroscience 33 (23), 9592-9600, 2013 | 435 | 2013 |
Inhibition of soluble TNF signaling in a mouse model of Alzheimer's disease prevents pre-plaque amyloid-associated neuropathology FE McAlpine, JK Lee, AS Harms, KA Ruhn, M Blurton-Jones, J Hong, ... Neurobiology of disease 34 (1), 163-177, 2009 | 313 | 2009 |
microRNA-155 regulates alpha-synuclein-induced inflammatory responses in models of Parkinson disease AD Thome, AS Harms, LA Volpicelli-Daley, DG Standaert Journal of Neuroscience 36 (8), 2383-2390, 2016 | 270 | 2016 |
Inhibition of the JAK/STAT pathway protects against α-synuclein-induced neuroinflammation and dopaminergic neurodegeneration H Qin, JA Buckley, X Li, Y Liu, TH Fox, GP Meares, H Yu, Z Yan, ... Journal of Neuroscience 36 (18), 5144-5159, 2016 | 265 | 2016 |
Periphery and brain, innate and adaptive immunity in Parkinson’s disease AS Harms, SA Ferreira, M Romero-Ramos Acta neuropathologica 141 (4), 527-545, 2021 | 239 | 2021 |
Peripheral monocyte entry is required for alpha-Synuclein induced inflammation and Neurodegeneration in a model of Parkinson disease AS Harms, AD Thome, Z Yan, AM Schonhoff, GP Williams, X Li, Y Liu, ... Experimental neurology 300, 179-187, 2018 | 232 | 2018 |
CD4 T cells mediate brain inflammation and neurodegeneration in a mouse model of Parkinson's disease GP Williams, AM Schonhoff, A Jurkuvenaite, NJ Gallups, DG Standaert, ... Brain 144 (7), 2047-2059, 2021 | 225 | 2021 |
α-Synuclein fibrils recruit peripheral immune cells in the rat brain prior to neurodegeneration AS Harms, V Delic, AD Thome, N Bryant, Z Liu, S Chandra, ... Acta neuropathologica communications 5, 1-16, 2017 | 201 | 2017 |
COVID-19 and possible links with Parkinson’s disease and parkinsonism: from bench to bedside D Sulzer, A Antonini, V Leta, A Nordvig, RJ Smeyne, JE Goldman, ... npj Parkinson's Disease 6 (1), 18, 2020 | 169 | 2020 |
Delayed dominant-negative TNF gene therapy halts progressive loss of nigral dopaminergic neurons in a rat model of Parkinson's disease AS Harms, CJ Barnum, KA Ruhn, S Varghese, I Treviño, A Blesch, ... Molecular Therapy 19 (1), 46-52, 2011 | 143 | 2011 |
Effects of estrogen receptor agonists on regulation of the inflammatory response in astrocytes from young adult and middle-aged female rats DK Lewis, AB Johnson, S Stohlgren, A Harms, F Sohrabji Journal of neuroimmunology 195 (1-2), 47-59, 2008 | 138 | 2008 |
How can rAAV‐α‐synuclein and the fibril α‐synuclein models advance our understanding of Parkinson's disease? LA Volpicelli‐Daley, D Kirik, LE Stoyka, DG Standaert, AS Harms Journal of neurochemistry 139, 131-155, 2016 | 131 | 2016 |
The gamma chain subunit of Fc receptors is required for alpha-synuclein-induced pro-inflammatory signaling in microglia S Cao, DG Standaert, AS Harms Journal of neuroinflammation 9, 1-11, 2012 | 125 | 2012 |
Regulator of G-protein signaling 10 promotes dopaminergic neuron survival via regulation of the microglial inflammatory response JK Lee, MK McCoy, AS Harms, KA Ruhn, SJ Gold, MG Tansey Journal of Neuroscience 28 (34), 8517-8528, 2008 | 110 | 2008 |
Innate and adaptive immune responses in Parkinson's disease AM Schonhoff, GP Williams, ZD Wallen, DG Standaert, AS Harms Progress in brain research 252, 169-216, 2020 | 103 | 2020 |
T cell infiltration in both human multiple system atrophy and a novel mouse model of the disease GP Williams, DJ Marmion, AM Schonhoff, A Jurkuvenaite, WJ Won, ... Acta Neuropathologica 139, 855-874, 2020 | 95 | 2020 |
Targeting of the class II transactivator attenuates inflammation and neurodegeneration in an alpha-synuclein model of Parkinson’s disease GP Williams, AM Schonhoff, A Jurkuvenaite, AD Thome, DG Standaert, ... Journal of neuroinflammation 15, 1-14, 2018 | 90 | 2018 |
Fractalkine signaling regulates the inflammatory response in an α-synuclein model of Parkinson disease AD Thome, DG Standaert, AS Harms PloS one 10 (10), e0140566, 2015 | 75 | 2015 |
Border-associated macrophages mediate the neuroinflammatory response in an alpha-synuclein model of Parkinson disease AM Schonhoff, DA Figge, GP Williams, A Jurkuvenaite, NJ Gallups, ... Nature communications 14 (1), 3754, 2023 | 68 | 2023 |
Regulation of microglia effector functions by tumor necrosis factor signaling AS Harms, JK Lee, TA Nguyen, J Chang, KM Ruhn, I Treviño, MG Tansey Glia 60 (2), 189-202, 2012 | 66 | 2012 |