עקוב אחר
Erich R. Kuechler
Erich R. Kuechler
Data Scientist, TechOps (CMC/GMP), AbCellera
כתובת אימייל מאומתת בדומיין abcellera.com
כותרת
צוטט על ידי
צוטט על ידי
שנה
Distinct Features of Stress Granule Proteins Predict Localization in Membraneless Organelles
ER Kuechler, PM Budzyńska, JP Bernardini, J Gsponer, T Mayor
Journal of Molecular Biology 432 (7), 2349-2368, 2020
762020
A variational linear-scaling framework to build practical, efficient next-generation orbital-based quantum force fields
TJ Giese, H Chen, T Dissanayake, GM Giambasu, H Heldenbrand, ...
Journal of chemical theory and computation 9 (3), 1417-1427, 2013
692013
Protein–Protein Interactions Mediated by Intrinsically Disordered Protein Regions Are Enriched in Missense Mutations
ETC Wong, V So, M Guron, ER Kuechler, N Malhis, JM Bui, J Gsponer
Biomolecules 10 (8), 1097, 2020
332020
Proteomic analysis reveals the direct recruitment of intrinsically disordered regions to stress granules
M Zhu, ER Kuechler, J Zhang, O Matalon, B Dubreuil, A Hofmann, ...
Journal of Cell Science 133 (13), 244657, 2020
302020
Charge-dependent many-body exchange and dispersion interactions in combined QM/MM simulations
ER Kuechler, TJ Giese, DM York
The Journal of Chemical Physics 143 (23), 2015
292015
Multiscale methods for computational RNA enzymology
MT Panteva, T Dissanayake, H Chen, BK Radak, ER Kuechler, ...
Methods in enzymology 553, 335-374, 2015
292015
Quantum mechanical study of solvent effects in a prototype SN2 reaction in solution: Cl− attack on CH3Cl
ER Kuechler, DM York
The Journal of Chemical Physics 140 (5), 2014
242014
NAD depletion mediates cytotoxicity in human neurons with autophagy deficiency
C Sun, E Seranova, MA Cohen, M Chipara, J Roberts, D Astuti, ...
Cell reports 42 (5), 2023
212023
GraPES: The Granule Protein Enrichment Server for prediction of biological condensate constituents
ER Kuechler, M Jacobson, T Mayor, J Gsponer
Nucleic Acids Research 50 (W1), W384-W391, 2022
142022
A multidimensional B-spline correction for accurate modeling sugar puckering in QM/MM simulations
M Huang, T Dissanayake, E Kuechler, BK Radak, TS Lee, TJ Giese, ...
Journal of chemical theory and computation 13 (9), 3975-3984, 2017
132017
Pulse labeling reveals the tail end of protein folding by proteome profiling
M Zhu, ER Kuechler, RWK Wong, G Calabrese, IM Sitarik, V Rana, ...
Cell reports 40 (3), 2022
112022
Shift of the insoluble content of the proteome in the aging mouse brain
C Molzahn, ER Kuechler, I Zemlyankina, L Nierves, T Ali, G Cole, J Wang, ...
Proceedings of the National Academy of Sciences 120 (45), e2310057120, 2023
92023
Comparison of biomolecular condensate localization and protein phase separation predictors
ER Kuechler, A Huang, JM Bui, T Mayor, J Gsponer
Biomolecules 13 (3), 527, 2023
72023
VR-SCOSMO: A smooth conductor-like screening model with charge-dependent radii for modeling chemical reactions
ER Kuechler, TJ Giese, DM York
The Journal of Chemical Physics 144 (16), 2016
52016
Protein feature analysis of heat shock induced ubiquitination sites reveals preferential modification site localization
ER Kuechler, A Rose, M Bolten, A Madero, S Kammoonah, S Colborne, ...
Journal of Proteomics 239, 104182, 2021
42021
Proteomic analysis reveals the recruitment of intrinsically disordered regions to stress granules
M Zhu, ER Kuechler, J Zhang, O Matalon, B Dubreuil, A Hofmann, ...
BioRxiv, 758599, 2019
22019
Analysis of protein levels and solubility in distinct brain regions reveals several elements of the protein homeostasis network that are impacted by aging
C Molzahn, E Kuechler, L Nierves, G Cole, J Wang, N Cashman, ...
bioRxiv, 2024.02. 28.582597, 2024
2024
Stress Granule Protein Features Allow for Accurate Prediction of Biological Condensate Localization with GraPES
E Kuechler, J Gsponer, T Mayor
The FASEB Journal 35, 2021
2021
Self-consistent charge-dependent interaction models for use in condensed phase molecular simulation
E Kuechler, T Giese, D York
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 250, 2015
2015
Charge-dependent non-bonded interaction methods for use in quantum mechanical modeling of condensed phase reactions
ER Kuechler
University of Minnesota, 2015
2015
המערכת אינה יכולה לבצע את הפעולה כעת. נסה שוב מאוחר יותר.
מאמרים 1–20