Design of protein-binding proteins from the target structure alone L Cao, B Coventry, I Goreshnik, B Huang, W Sheffler, JS Park, KM Jude, ... Nature 605 (7910), 551-560, 2022 | 387 | 2022 |
Improving de novo protein binder design with deep learning NR Bennett, B Coventry, I Goreshnik, B Huang, A Allen, D Vafeados, ... Nature Communications 14 (1), 2625, 2023 | 190 | 2023 |
Application of 3D cultured multicellular spheroid tumor models in tumor-targeted drug delivery system research BW Huang, JQ Gao Journal of controlled release 270, 246-259, 2018 | 173 | 2018 |
Hypoxia-tropic protein nanocages for modulation of tumor-and chemotherapy-associated hypoxia X Huang, J Zhuang, SW Chung, B Huang, G Halpert, K Negron, X Sun, ... Acs Nano 13 (1), 236-247, 2018 | 77 | 2018 |
Atomically accurate de novo design of single-domain antibodies NR Bennett, JL Watson, RJ Ragotte, AJ Borst, DL See, C Weidle, ... biorxiv, 2024 | 60 | 2024 |
Robust de novo design of protein binding proteins from target structural information alone L Cao, B Coventry, I Goreshnik, B Huang, JS Park, KM Jude, I Marković, ... BioRxiv, 2021.09. 04.459002, 2021 | 15 | 2021 |
Randomized gates eliminate bias in sort‐seq assays BL Trippe, B Huang, EA DeBenedictis, B Coventry, N Bhattacharya, ... Protein Science 31 (9), e4401, 2022 | 13 | 2022 |
Designed endocytosis-inducing proteins degrade targets and amplify signals B Huang, M Abedi, G Ahn, B Coventry, I Sappington, C Tang, R Wang, ... Nature, 1-9, 2024 | 8 | 2024 |
De novo design of miniprotein antagonists of cytokine storm inducers B Huang, B Coventry, MT Borowska, DC Arhontoulis, M Exposit, M Abedi, ... Nature Communications 15 (1), 7064, 2024 | 7 | 2024 |
Designed endocytosis-triggering proteins mediate targeted degradation B Huang, M Abedi, G Ahn, B Coventry, I Sappington, R Wang, ... BioRxiv, 2023 | 7 | 2023 |
Four-component protein nanocages designed by programmed symmetry breaking S Lee, RD Kibler, G Ahn, Y Hsia, AJ Borst, A Philomin, MA Kennedy, ... Nature, 1-7, 2024 | 6 | 2024 |
Transcriptome-wide elucidation of liposomal formulations for anticancer drug delivery Y Li, M Wang, BW Huang, Y Ping, J You, JQ Gao International Journal of Nanomedicine, 8557-8572, 2017 | 6 | 2017 |
Target-conditioned diffusion generates potent TNFR superfamily antagonists and agonists M Glögl, A Krishnakumar, RJ Ragotte, I Goreshnik, B Coventry, AK Bera, ... Science 386 (6726), 1154-1161, 2024 | 5 | 2024 |
Engineered receptors for soluble cellular communication and disease sensing DI Piraner, MH Abedi, MJ Duran Gonzalez, A Chazin-Gray, A Lin, I Zhu, ... Nature, 1-3, 2024 | 5 | 2024 |
Atomically accurate de novo design of single-domain antibodies. bioRxiv NR Bennett, JL Watson, RJ Ragotte, AJ Borst, DL See, C Weidle, ... Published online March, 2024 | 5 | 2024 |
Design of high affinity binders to convex protein target sites W Yang, DR Hicks, A Ghosh, TA Schwartze, B Conventry, I Goreshnik, ... bioRxiv, 2024 | 4 | 2024 |
Improved protein binder design using beta-pairing targeted RFdiffusion I Sappington, M Toul, DS Lee, SA Robinson, I Goreshnik, C McCurdy, ... bioRxiv, 2024.10. 11.617496, 2024 | 2 | 2024 |
De novo designed Hsp70 activator dissolves intracellular condensates JZ Zhang, N Greenwood, J Hernandez, JT Cuperus, B Huang, BD Ryder, ... Cell Chemical Biology, 2023 | 2 | 2023 |
Engineered receptors for soluble cell-to-cell communication DI Piraner, MH Abedi, MJD Gonzalez, A Chazin-Gray, I Zhu, ... bioRxiv, 2024.09. 17.613377, 2024 | 1 | 2024 |
Design of high-affinity binders to immune modulating receptors for cancer immunotherapy W Yang, DR Hicks, A Ghosh, TA Schwartze, B Conventry, I Goreshnik, ... Nature Communications 16 (1), 2001, 2025 | | 2025 |