Reference-based analysis of lung single-cell sequencing reveals a transitional profibrotic macrophage D Aran, AP Looney, L Liu, E Wu, V Fong, A Hsu, S Chak, RP Naikawadi, ... Nature immunology 20 (2), 163-172, 2019 | 3492 | 2019 |
Therapeutic targeting of TAZ and YAP by dimethyl fumarate in systemic sclerosis fibrosis T Toyama, AP Looney, BM Baker, L Stawski, P Haines, R Simms, ... Journal of Investigative Dermatology 138 (1), 78-88, 2018 | 96 | 2018 |
Dimethyl Fumarate ameliorates pulmonary arterial hypertension and lung fibrosis by targeting multiple pathways AP Grzegorzewska, F Seta, R Han, CA Czajka, K Makino, L Stawski, ... Scientific reports 7 (1), 41605, 2017 | 76 | 2017 |
SIN-dependent phosphoinhibition of formin multimerization controls fission yeast cytokinesis KA Bohnert, AP Grzegorzewska, AH Willet, CW Vander Kooi, DR Kovar, ... Genes & development 27 (19), 2164-2177, 2013 | 64 | 2013 |
Synergistic role of endothelial ERG and FLI1 in mediating pulmonary vascular homeostasis AP Looney, R Han, L Stawski, G Marden, M Iwamoto, M Trojanowska American Journal of Respiratory Cell and Molecular Biology 57 (1), 121-131, 2017 | 39 | 2017 |
Controlled loading of albumin-drug conjugates ex vivo for enhanced drug delivery and antitumor efficacy X Liu, RP Mohanty, EY Maier, X Peng, S Wulfe, AP Looney, KL Aung, ... Journal of Controlled Release 328, 1-12, 2020 | 34 | 2020 |
Fission yeast profilin is tailored to facilitate actin assembly by the cytokinesis formin Cdc12 AJ Bestul, JR Christensen, AP Grzegorzewska, TA Burke, JA Sees, ... Molecular biology of the cell 26 (2), 283-293, 2015 | 15 | 2015 |
Arhgef12 drives IL17A-induced airway contractility and airway hyperresponsiveness in mice V Fong, A Hsu, E Wu, AP Looney, P Ganesan, X Ren, D Sheppard, ... JCI insight 3 (21), e123578, 2018 | 14 | 2018 |
Reference-based annotation of single cell transcriptomes identifies a profibrotic macrophage niche after tissue injury D Aran, AP Looney, L Liu, V Fong, A Hsu, PJ Wolters, A Abate, AJ Butte, ... BioRxiv, 284604, 2018 | 12 | 2018 |
GATA6 coordinates cross-talk between BMP10 and oxidative stress axis in pulmonary arterial hypertension T Toyama, TV Kudryashova, A Ichihara, S Lenna, A Looney, Y Shen, ... Scientific reports 13 (1), 6593, 2023 | 11 | 2023 |
Covalent JNK inhibitor, JNK-IN-8, suppresses tumor growth in triple-negative breast cancer by activating TFEB-and TFE3-mediated lysosome biogenesis and autophagy M Soleimani, A Somma, T Kaoud, R Goyal, J Bustamante, DC Wylie, ... Molecular Cancer Therapeutics 21 (10), 1547-1560, 2022 | 11 | 2022 |
Fibroblast Gap-closure Assay-Microscopy-based in vitro Assay Measuring the Migration of Murine Fibroblasts AP Looney, M Bhattacharya Bio-protocol 9 (16), 2019 | 3 | 2019 |
Endothelial GATA6 Coordinates Cross-Talk Between BMP and Oxidative Stress Axis in Pulmonary Arterial Hypertension A Ichihara, T Toyama, T Kudryashova, S Lenna, A Looney, Y Shen, ... D25. O BRAVE NEW WORLD! OMICS, SYSTEM BIOLOGY, AND NEW MOLECULAR MECHANISMS …, 2020 | 1 | 2020 |
Single-cell RNA-seq reveals profibrotic macrophages in lung fibrosis D Aran, AP Looney, L Liu, V Fong, A Hsu, PJ Wolters, A Abate, AJ Butte, ... bioRxiv, 2018 | 1 | 2018 |
Covalent JNK inhibitor, JNK-IN-8, suppresses tumor growth in triple-negative breast cancer in part by activating lysosome biogenesis and autophagy via TFEB and TFE3 M Soleimani, T Kaoud, A Somma, J Bustamante, DC Wylie, N Holay, ... Cancer Research 82 (12_Supplement), 4109-4109, 2022 | | 2022 |
An allosteric SHP2 inhibitor RMC-4550 induces immunogenicity in pancreatic adenocarcinoma (PDA) and enhances the cytotoxicity of CD8+ effector T cells A Looney, U Giri, Y Zhu, A Somma, N Holay, M Soleimani, H Gandhi, ... Cancer Research 82 (12_Supplement), 1298-1298, 2022 | | 2022 |
Controlled Loading of Albumin-Drug Pre-Conjugates for Treatment of Pancreatic Cancer X Liu, R Mohanty, EY Maier, X Peng, S Wulfe, AP Looney, KL Aung, ... 2020 Virtual AIChE Annual Meeting, 2020 | | 2020 |
Single Cell Analysis of Disease-Associated Macrophages in Lung Fibrosis A Looney, D Aran, L Liu, A Hsu, V Fong, D Sheppard, A Abate, A Butte, ... C21. ALVEOLAR MACROPHAGE DIVERSITY IN LUNG INJURY AND REPAIR, A4480-A4480, 2018 | | 2018 |
ArhGEF12 Is Necessary For TNFα-Induced RhoA Activation In Airway Smooth Muscle V Fong, A Hsu, P Ganesan, A Grzegorzewska, X Huang, D Sheppard, ... C35. ASTHMA AND ALLERGY CELLULAR INVESTIGATIONS, A5281-A5281, 2017 | | 2017 |
C35 ASTHMA AND ALLERGY CELLULAR INVESTIGATIONS: Arhgef12 Is Necessary For Tnfα-Induced Rhoa Activation In Airway Smooth Muscle V Fong, A Hsu, P Ganesan, A Grzegorzewska, X Huang, D Sheppard, ... American Journal of Respiratory and Critical Care Medicine 195, 2017 | | 2017 |