Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis G Bergers, R Brekken, G McMahon, TH Vu, T Itoh, K Tamaki, K Tanzawa, ... Nature cell biology 2 (10), 737-744, 2000 | 3511 | 2000 |
Hypoxia-inducible factor 1α induces fibrosis and insulin resistance in white adipose tissue N Halberg, T Khan, ME Trujillo, I Wernstedt-Asterholm, AD Attie, ... Molecular and cellular biology 29 (16), 4467-4483, 2009 | 1064 | 2009 |
SPARC, a matricellular protein: at the crossroads of cell–matrix RA Brekken, EH Sage Matrix Biology 19 (7), 569-580, 2000 | 1037 | 2000 |
Pancreatic cancer stroma: an update on therapeutic targeting strategies AN Hosein, RA Brekken, A Maitra Nature reviews Gastroenterology & hepatology 17 (8), 487-505, 2020 | 740 | 2020 |
Phosphatidylserine is a global immunosuppressive signal in efferocytosis, infectious disease, and cancer RB Birge, S Boeltz, S Kumar, J Carlson, J Wanderley, D Calianese, ... Cell Death & Differentiation 23 (6), 962-978, 2016 | 692 | 2016 |
Dichotomous effects of VEGF-A on adipose tissue dysfunction K Sun, IW Asterholm, CM Kusminski, AC Bueno, ZV Wang, JW Pollard, ... Proceedings of the national academy of sciences 109 (15), 5874-5879, 2012 | 571 | 2012 |
Role of VEGF-A in vascularization of pancreatic islets E Lammert, G Gu, M McLaughlin, D Brown, R Brekken, LC Murtaugh, ... Current Biology 13 (12), 1070-1074, 2003 | 493 | 2003 |
Selective inhibition of vascular endothelial growth factor (VEGF) receptor 2 (KDR/Flk-1) activity by a monoclonal anti-VEGF antibody blocks tumor growth in mice RA Brekken, JP Overholser, VA Stastny, J Waltenberger, JD Minna, ... Cancer research 60 (18), 5117-5124, 2000 | 487 | 2000 |
Antibody compositions for selectively inhibiting VEGF PE Thorpe, RA Brekken US Patent 6,342,219, 2002 | 464 | 2002 |
Alternatively spliced vascular endothelial growth factor receptor-2 is an essential endogenous inhibitor of lymphatic vessel growth RJC Albuquerque, T Hayashi, WG Cho, ME Kleinman, S Dridi, A Takeda, ... Nature medicine 15 (9), 1023-1030, 2009 | 457 | 2009 |
Soluble Eph A receptors inhibit tumor angiogenesis and progression in vivo DM Brantley, N Cheng, EJ Thompson, Q Lin, RA Brekken, PE Thorpe, ... Oncogene 21 (46), 7011-7026, 2002 | 409 | 2002 |
27-Hydroxycholesterol promotes cell-autonomous, ER-positive breast cancer growth Q Wu, T Ishikawa, R Sirianni, H Tang, JG McDonald, IS Yuhanna, ... Cell reports 5 (3), 637-645, 2013 | 373 | 2013 |
A small molecule modulates Jumonji histone demethylase activity and selectively inhibits cancer growth L Wang, J Chang, D Varghese, M Dellinger, S Kumar, AM Best, J Ruiz, ... Nature communications 4 (1), 2035, 2013 | 346 | 2013 |
Angiogenic role of LYVE-1–positive macrophages in adipose tissue CH Cho, Y Jun Koh, J Han, HK Sung, H Jong Lee, T Morisada, ... Circulation research 100 (4), e47-e57, 2007 | 345 | 2007 |
Mesothelial cell-derived antigen-presenting cancer-associated fibroblasts induce expansion of regulatory T cells in pancreatic cancer H Huang, Z Wang, Y Zhang, RN Pradhan, D Ganguly, R Chandra, ... Cancer cell 40 (6), 656-673. e7, 2022 | 333 | 2022 |
Monitoring response to anticancer therapy by targeting microbubbles to tumor vasculature G Korpanty, JG Carbon, PA Grayburn, JB Fleming, RA Brekken Clinical Cancer Research 13 (1), 323-330, 2007 | 333 | 2007 |
Vascular endothelial growth factor promotes fibrosis resolution and repair in mice L Yang, J Kwon, Y Popov, GB Gajdos, T Ordog, RA Brekken, ... Gastroenterology 146 (5), 1339-1350. e1, 2014 | 295 | 2014 |
A peptoid “antibody surrogate” that antagonizes VEGF receptor 2 activity DG Udugamasooriya, SP Dineen, RA Brekken, T Kodadek Journal of the American Chemical Society 130 (17), 5744-5752, 2008 | 286 | 2008 |
Cellular heterogeneity during mouse pancreatic ductal adenocarcinoma progression at single-cell resolution AN Hosein, H Huang, Z Wang, K Parmar, W Du, J Huang, A Maitra, ... JCI insight 4 (16), e129212, 2019 | 277 | 2019 |
Non-nuclear estrogen receptor α signaling promotes cardiovascular protection but not uterine or breast cancer growth in mice KL Chambliss, Q Wu, S Oltmann, ES Konaniah, M Umetani, KS Korach, ... The Journal of clinical investigation 120 (7), 2319-2330, 2010 | 276 | 2010 |